Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.
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Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue. / Tiburcy, Malte; Didié, Michael; Boy, Oliver; Christalla, Peter; Döker, Stephan; Naito, Hiroshi; Karikkineth, Bijoy Chandapillai; El-Armouche, Ali; Grimm, Michael; Nose, Monika; Eschenhagen, Thomas; Zieseniss, Anke; Katschinksi, Doerthe M; Hamdani, Nazha; Linke, Wolfgang A; Yin, Xiaoke; Mayr, Manuel; Zimmermann, Wolfram-Hubertus.
In: CIRC RES, Vol. 109, No. 10, 10, 2011, p. 1105-1114.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.
AU - Tiburcy, Malte
AU - Didié, Michael
AU - Boy, Oliver
AU - Christalla, Peter
AU - Döker, Stephan
AU - Naito, Hiroshi
AU - Karikkineth, Bijoy Chandapillai
AU - El-Armouche, Ali
AU - Grimm, Michael
AU - Nose, Monika
AU - Eschenhagen, Thomas
AU - Zieseniss, Anke
AU - Katschinksi, Doerthe M
AU - Hamdani, Nazha
AU - Linke, Wolfgang A
AU - Yin, Xiaoke
AU - Mayr, Manuel
AU - Zimmermann, Wolfram-Hubertus
PY - 2011
Y1 - 2011
N2 - Cardiac tissue engineering should provide "realistic" in vitro heart muscle models and surrogate tissue for myocardial repair. For either application, engineered myocardium should display features of native myocardium, including terminal differentiation, organotypic maturation, and hypertrophic growth.
AB - Cardiac tissue engineering should provide "realistic" in vitro heart muscle models and surrogate tissue for myocardial repair. For either application, engineered myocardium should display features of native myocardium, including terminal differentiation, organotypic maturation, and hypertrophic growth.
KW - Animals
KW - Age Factors
KW - Cells, Cultured
KW - Rats
KW - Apoptosis
KW - Gene Expression Regulation, Developmental
KW - Aging
KW - Rats, Wistar
KW - Animals, Newborn
KW - Cell Culture Techniques
KW - Cell Proliferation
KW - Proteomics/methods
KW - Tissue Engineering
KW - Extracellular Matrix/metabolism
KW - Cardiomegaly/genetics/metabolism/pathology/physiopathology
KW - Cell Differentiation/genetics
KW - Myocardial Contraction
KW - Myocardium/metabolism/pathology
KW - Myocytes, Cardiac/metabolism/pathology
KW - Organogenesis
KW - Regeneration/genetics
KW - Sarcomeres/metabolism/pathology
KW - Animals
KW - Age Factors
KW - Cells, Cultured
KW - Rats
KW - Apoptosis
KW - Gene Expression Regulation, Developmental
KW - Aging
KW - Rats, Wistar
KW - Animals, Newborn
KW - Cell Culture Techniques
KW - Cell Proliferation
KW - Proteomics/methods
KW - Tissue Engineering
KW - Extracellular Matrix/metabolism
KW - Cardiomegaly/genetics/metabolism/pathology/physiopathology
KW - Cell Differentiation/genetics
KW - Myocardial Contraction
KW - Myocardium/metabolism/pathology
KW - Myocytes, Cardiac/metabolism/pathology
KW - Organogenesis
KW - Regeneration/genetics
KW - Sarcomeres/metabolism/pathology
M3 - SCORING: Journal article
VL - 109
SP - 1105
EP - 1114
JO - CIRC RES
JF - CIRC RES
SN - 0009-7330
IS - 10
M1 - 10
ER -