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Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment

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Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. / Alegiani, Anna C; Dorn, Franziska; Herzberg, Moriz; Wollenweber, Frank A; Kellert, Lars; Siebert, Eberhard; Nolte, Christian H; von Rennenberg, Regina; Hattingen, Elke; Petzold, Gabor C; Bode, Felix J; Pfeilschifter, Waltraud; Schäfer, Jan H; Wagner, Marlies; Röther, Joachim; Eckert, Bernd; Kraft, Peter; Pham, Mirko; Boeckh-Behrens, Tobias; Wunderlich, Silke; Bernkopf, Kathleen; Reich, Arno; Wiesmann, Martin; Mpotsaris, Anastasios; Psychogios, Marios; Liman, Jan; Maier, Ilko; Berrouschot, Jörg; Bormann, Albrecht; Limmroth, Volker; Spreer, Joachim; Petersen, Martina; Krause, Lars; Lowens, Stephan; Kraemer, Christoffer; Zweynert, Sarah; Lange, Kristin S; Thonke, Sven; Kastrup, Andreas; Papanagiotou, Panagiotis; Alber, Burkhard; Braun, Michael; Fiehler, Jens; Gerloff, Christian; Dichgans, Martin; Thomalla, Götz.

In: INT J STROKE, Vol. 14, No. 4, 06.2019, p. 372-380.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Alegiani, AC, Dorn, F, Herzberg, M, Wollenweber, FA, Kellert, L, Siebert, E, Nolte, CH, von Rennenberg, R, Hattingen, E, Petzold, GC, Bode, FJ, Pfeilschifter, W, Schäfer, JH, Wagner, M, Röther, J, Eckert, B, Kraft, P, Pham, M, Boeckh-Behrens, T, Wunderlich, S, Bernkopf, K, Reich, A, Wiesmann, M, Mpotsaris, A, Psychogios, M, Liman, J, Maier, I, Berrouschot, J, Bormann, A, Limmroth, V, Spreer, J, Petersen, M, Krause, L, Lowens, S, Kraemer, C, Zweynert, S, Lange, KS, Thonke, S, Kastrup, A, Papanagiotou, P, Alber, B, Braun, M, Fiehler, J, Gerloff, C, Dichgans, M & Thomalla, G 2019, 'Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment', INT J STROKE, vol. 14, no. 4, pp. 372-380. https://doi.org/10.1177/1747493018806199

APA

Alegiani, A. C., Dorn, F., Herzberg, M., Wollenweber, F. A., Kellert, L., Siebert, E., Nolte, C. H., von Rennenberg, R., Hattingen, E., Petzold, G. C., Bode, F. J., Pfeilschifter, W., Schäfer, J. H., Wagner, M., Röther, J., Eckert, B., Kraft, P., Pham, M., Boeckh-Behrens, T., ... Thomalla, G. (2019). Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. INT J STROKE, 14(4), 372-380. https://doi.org/10.1177/1747493018806199

Vancouver

Alegiani AC, Dorn F, Herzberg M, Wollenweber FA, Kellert L, Siebert E et al. Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. INT J STROKE. 2019 Jun;14(4):372-380. https://doi.org/10.1177/1747493018806199

Bibtex

@article{dfe08996370f4eb18db6c64a12da363d,
title = "Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment",
abstract = "BACKGROUND: Endovascular treatment has become standard of care for the treatment of acute ischemic stroke with large vessel occlusion. However, patients treated in clinical practice differ from the selected populations randomized in clinical trials.AIMS: The German Stroke Registry Endovascular Treatment (GSR-ET) aims at a systematic evaluation of outcome, safety, and process parameters of endovascular stroke treatment in standard of care in Germany.METHODS: The GSR-ET is an academic, independent, prospective, multicenter, observational registry study. Participating stroke centers from all over of Germany consecutively enroll patients transferred to the angiography suite with an intention to be treated with endovascular stroke treatment. Patients receive regular care. Data are collected as part of clinical routine. Baseline clinical and procedural information and clinical follow-up information after 90 days are recorded. Here, we present an analysis of baseline data of the first 1662 patients included in the GSR-ET.RESULTS: The registry was established in June 2015. By 31 December 2017, 1662 patients were enrolled in 23 active sites. Mean age was 72 ± 13 years, 50% were female, and median National Institutes of Health Stroke Scale on admission was 15 (IQR 10-19), 88% had anterior circulation occlusion. Median ASPECT score was 8 (IQR 7-10) prior to intervention. Fifty-nine percent of patients received intravenous thrombolysis prior to thrombectomy. Mean {"}onset-to-groin{"} time was 224 ± 176 min.CONCLUSIONS: Baseline characteristics of stroke patients undergoing thrombectomy in clinical practice differ from those in the randomized trials. The GSR-ET will provide valuable insights into practices of endovascular treatment in routine care of acute ischemic stroke. (GSR-ET ClinicalTrials.gov Identifier: NCT03356392.).",
keywords = "Journal Article",
author = "Alegiani, {Anna C} and Franziska Dorn and Moriz Herzberg and Wollenweber, {Frank A} and Lars Kellert and Eberhard Siebert and Nolte, {Christian H} and {von Rennenberg}, Regina and Elke Hattingen and Petzold, {Gabor C} and Bode, {Felix J} and Waltraud Pfeilschifter and Sch{\"a}fer, {Jan H} and Marlies Wagner and Joachim R{\"o}ther and Bernd Eckert and Peter Kraft and Mirko Pham and Tobias Boeckh-Behrens and Silke Wunderlich and Kathleen Bernkopf and Arno Reich and Martin Wiesmann and Anastasios Mpotsaris and Marios Psychogios and Jan Liman and Ilko Maier and J{\"o}rg Berrouschot and Albrecht Bormann and Volker Limmroth and Joachim Spreer and Martina Petersen and Lars Krause and Stephan Lowens and Christoffer Kraemer and Sarah Zweynert and Lange, {Kristin S} and Sven Thonke and Andreas Kastrup and Panagiotis Papanagiotou and Burkhard Alber and Michael Braun and Jens Fiehler and Christian Gerloff and Martin Dichgans and G{\"o}tz Thomalla",
year = "2019",
month = jun,
doi = "10.1177/1747493018806199",
language = "English",
volume = "14",
pages = "372--380",
journal = "INT J STROKE",
issn = "1747-4930",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment

AU - Alegiani, Anna C

AU - Dorn, Franziska

AU - Herzberg, Moriz

AU - Wollenweber, Frank A

AU - Kellert, Lars

AU - Siebert, Eberhard

AU - Nolte, Christian H

AU - von Rennenberg, Regina

AU - Hattingen, Elke

AU - Petzold, Gabor C

AU - Bode, Felix J

AU - Pfeilschifter, Waltraud

AU - Schäfer, Jan H

AU - Wagner, Marlies

AU - Röther, Joachim

AU - Eckert, Bernd

AU - Kraft, Peter

AU - Pham, Mirko

AU - Boeckh-Behrens, Tobias

AU - Wunderlich, Silke

AU - Bernkopf, Kathleen

AU - Reich, Arno

AU - Wiesmann, Martin

AU - Mpotsaris, Anastasios

AU - Psychogios, Marios

AU - Liman, Jan

AU - Maier, Ilko

AU - Berrouschot, Jörg

AU - Bormann, Albrecht

AU - Limmroth, Volker

AU - Spreer, Joachim

AU - Petersen, Martina

AU - Krause, Lars

AU - Lowens, Stephan

AU - Kraemer, Christoffer

AU - Zweynert, Sarah

AU - Lange, Kristin S

AU - Thonke, Sven

AU - Kastrup, Andreas

AU - Papanagiotou, Panagiotis

AU - Alber, Burkhard

AU - Braun, Michael

AU - Fiehler, Jens

AU - Gerloff, Christian

AU - Dichgans, Martin

AU - Thomalla, Götz

PY - 2019/6

Y1 - 2019/6

N2 - BACKGROUND: Endovascular treatment has become standard of care for the treatment of acute ischemic stroke with large vessel occlusion. However, patients treated in clinical practice differ from the selected populations randomized in clinical trials.AIMS: The German Stroke Registry Endovascular Treatment (GSR-ET) aims at a systematic evaluation of outcome, safety, and process parameters of endovascular stroke treatment in standard of care in Germany.METHODS: The GSR-ET is an academic, independent, prospective, multicenter, observational registry study. Participating stroke centers from all over of Germany consecutively enroll patients transferred to the angiography suite with an intention to be treated with endovascular stroke treatment. Patients receive regular care. Data are collected as part of clinical routine. Baseline clinical and procedural information and clinical follow-up information after 90 days are recorded. Here, we present an analysis of baseline data of the first 1662 patients included in the GSR-ET.RESULTS: The registry was established in June 2015. By 31 December 2017, 1662 patients were enrolled in 23 active sites. Mean age was 72 ± 13 years, 50% were female, and median National Institutes of Health Stroke Scale on admission was 15 (IQR 10-19), 88% had anterior circulation occlusion. Median ASPECT score was 8 (IQR 7-10) prior to intervention. Fifty-nine percent of patients received intravenous thrombolysis prior to thrombectomy. Mean "onset-to-groin" time was 224 ± 176 min.CONCLUSIONS: Baseline characteristics of stroke patients undergoing thrombectomy in clinical practice differ from those in the randomized trials. The GSR-ET will provide valuable insights into practices of endovascular treatment in routine care of acute ischemic stroke. (GSR-ET ClinicalTrials.gov Identifier: NCT03356392.).

AB - BACKGROUND: Endovascular treatment has become standard of care for the treatment of acute ischemic stroke with large vessel occlusion. However, patients treated in clinical practice differ from the selected populations randomized in clinical trials.AIMS: The German Stroke Registry Endovascular Treatment (GSR-ET) aims at a systematic evaluation of outcome, safety, and process parameters of endovascular stroke treatment in standard of care in Germany.METHODS: The GSR-ET is an academic, independent, prospective, multicenter, observational registry study. Participating stroke centers from all over of Germany consecutively enroll patients transferred to the angiography suite with an intention to be treated with endovascular stroke treatment. Patients receive regular care. Data are collected as part of clinical routine. Baseline clinical and procedural information and clinical follow-up information after 90 days are recorded. Here, we present an analysis of baseline data of the first 1662 patients included in the GSR-ET.RESULTS: The registry was established in June 2015. By 31 December 2017, 1662 patients were enrolled in 23 active sites. Mean age was 72 ± 13 years, 50% were female, and median National Institutes of Health Stroke Scale on admission was 15 (IQR 10-19), 88% had anterior circulation occlusion. Median ASPECT score was 8 (IQR 7-10) prior to intervention. Fifty-nine percent of patients received intravenous thrombolysis prior to thrombectomy. Mean "onset-to-groin" time was 224 ± 176 min.CONCLUSIONS: Baseline characteristics of stroke patients undergoing thrombectomy in clinical practice differ from those in the randomized trials. The GSR-ET will provide valuable insights into practices of endovascular treatment in routine care of acute ischemic stroke. (GSR-ET ClinicalTrials.gov Identifier: NCT03356392.).

KW - Journal Article

U2 - 10.1177/1747493018806199

DO - 10.1177/1747493018806199

M3 - SCORING: Journal article

C2 - 30346260

VL - 14

SP - 372

EP - 380

JO - INT J STROKE

JF - INT J STROKE

SN - 1747-4930

IS - 4

ER -