Synaptogenesis and heritable aspects of executive attention

John A Fossella; Tobias Sommer-Blöchl; Jin Fan; Don Pfaff; Michael I Posner

doi:10.1002/mrdd.10078

Synaptogenesis and heritable aspects of executive attention

Standard

Synaptogenesis and heritable aspects of executive attention. / Fossella, John A; Sommer-Blöchl, Tobias; Fan, Jin; Pfaff, Don; Posner, Michael I.

In: MENT RETARD DEV D R, Vol. 9, No. 3, 2003, p. 178-83.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Fossella, JA, Sommer-Blöchl, T, Fan, J, Pfaff, D & Posner, MI 2003, 'Synaptogenesis and heritable aspects of executive attention', MENT RETARD DEV D R, vol. 9, no. 3, pp. 178-83. https://doi.org/10.1002/mrdd.10078

APA

Fossella, J. A., Sommer-Blöchl, T., Fan, J., Pfaff, D., & Posner, M. I. (2003). Synaptogenesis and heritable aspects of executive attention. MENT RETARD DEV D R, 9(3), 178-83. https://doi.org/10.1002/mrdd.10078

Vancouver

Fossella JA, Sommer-Blöchl T, Fan J, Pfaff D, Posner MI. Synaptogenesis and heritable aspects of executive attention. MENT RETARD DEV D R. 2003;9(3):178-83. https://doi.org/10.1002/mrdd.10078

Bibtex

@article{6b8364f50f274ffd8443d51339425365,

title = "Synaptogenesis and heritable aspects of executive attention",

abstract = "In humans, changes in brain structure and function can be measured non-invasively during postnatal development. In animals, advanced optical imaging measures can track the formation of synapses during learning and behavior. With the recent progress in these technologies, it is appropriate to begin to assess how the physiological processes of synapse, circuit, and neural network formation relate to the process of cognitive development. Of particular interest is the development of executive function, which develops more gradually in humans. One approach that has shown promise is molecular genetics. The completion of the human genome project and the human genome diversity project make it straightforward to ask whether variation in a particular gene correlates with variation in behavior, brain structure, brain activity, or all of the above. Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology.",

keywords = "Alleles, Attention, Attention Deficit Disorder with Hyperactivity, Cognition Disorders, DNA Mutational Analysis, DNA Primers, Fragile X Syndrome, Humans, Intellectual Disability, Membrane Proteins, Molecular Biology, Nerve Tissue Proteins, Point Mutation, Polymerase Chain Reaction, RGS Proteins, Receptors, Dopamine D2, Receptors, N-Methyl-D-Aspartate, Synapses, Synaptosomal-Associated Protein 25",

author = "Fossella, {John A} and Tobias Sommer-Bl{\"o}chl and Jin Fan and Don Pfaff and Posner, {Michael I}",

year = "2003",

doi = "10.1002/mrdd.10078",

language = "English",

volume = "9",

pages = "178--83",

journal = "MENT RETARD DEV D R",

issn = "1080-4013",

publisher = "Wiley-Liss Inc.",

number = "3",

}

RIS

TY - JOUR

T1 - Synaptogenesis and heritable aspects of executive attention

AU - Fossella, John A

AU - Sommer-Blöchl, Tobias

AU - Fan, Jin

AU - Pfaff, Don

AU - Posner, Michael I

PY - 2003

Y1 - 2003

N2 - In humans, changes in brain structure and function can be measured non-invasively during postnatal development. In animals, advanced optical imaging measures can track the formation of synapses during learning and behavior. With the recent progress in these technologies, it is appropriate to begin to assess how the physiological processes of synapse, circuit, and neural network formation relate to the process of cognitive development. Of particular interest is the development of executive function, which develops more gradually in humans. One approach that has shown promise is molecular genetics. The completion of the human genome project and the human genome diversity project make it straightforward to ask whether variation in a particular gene correlates with variation in behavior, brain structure, brain activity, or all of the above. Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology.

AB - In humans, changes in brain structure and function can be measured non-invasively during postnatal development. In animals, advanced optical imaging measures can track the formation of synapses during learning and behavior. With the recent progress in these technologies, it is appropriate to begin to assess how the physiological processes of synapse, circuit, and neural network formation relate to the process of cognitive development. Of particular interest is the development of executive function, which develops more gradually in humans. One approach that has shown promise is molecular genetics. The completion of the human genome project and the human genome diversity project make it straightforward to ask whether variation in a particular gene correlates with variation in behavior, brain structure, brain activity, or all of the above. Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology.

KW - Alleles

KW - Attention

KW - Attention Deficit Disorder with Hyperactivity

KW - Cognition Disorders

KW - DNA Mutational Analysis

KW - DNA Primers

KW - Fragile X Syndrome

KW - Humans

KW - Intellectual Disability

KW - Membrane Proteins

KW - Molecular Biology

KW - Nerve Tissue Proteins

KW - Point Mutation

KW - Polymerase Chain Reaction

KW - RGS Proteins

KW - Receptors, Dopamine D2

KW - Receptors, N-Methyl-D-Aspartate

KW - Synapses

KW - Synaptosomal-Associated Protein 25

U2 - 10.1002/mrdd.10078

DO - 10.1002/mrdd.10078

M3 - SCORING: Journal article

C2 - 12953297

VL - 9

SP - 178

EP - 183

JO - MENT RETARD DEV D R

JF - MENT RETARD DEV D R

SN - 1080-4013

IS - 3

ER -