Synaptogenesis and heritable aspects of executive attention
Standard
Synaptogenesis and heritable aspects of executive attention. / Fossella, John A; Sommer-Blöchl, Tobias; Fan, Jin; Pfaff, Don; Posner, Michael I.
in: MENT RETARD DEV D R, Jahrgang 9, Nr. 3, 2003, S. 178-83.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Synaptogenesis and heritable aspects of executive attention
AU - Fossella, John A
AU - Sommer-Blöchl, Tobias
AU - Fan, Jin
AU - Pfaff, Don
AU - Posner, Michael I
N1 - Copyright 2003 Wiley-Liss, Inc.
PY - 2003
Y1 - 2003
N2 - In humans, changes in brain structure and function can be measured non-invasively during postnatal development. In animals, advanced optical imaging measures can track the formation of synapses during learning and behavior. With the recent progress in these technologies, it is appropriate to begin to assess how the physiological processes of synapse, circuit, and neural network formation relate to the process of cognitive development. Of particular interest is the development of executive function, which develops more gradually in humans. One approach that has shown promise is molecular genetics. The completion of the human genome project and the human genome diversity project make it straightforward to ask whether variation in a particular gene correlates with variation in behavior, brain structure, brain activity, or all of the above. Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology.
AB - In humans, changes in brain structure and function can be measured non-invasively during postnatal development. In animals, advanced optical imaging measures can track the formation of synapses during learning and behavior. With the recent progress in these technologies, it is appropriate to begin to assess how the physiological processes of synapse, circuit, and neural network formation relate to the process of cognitive development. Of particular interest is the development of executive function, which develops more gradually in humans. One approach that has shown promise is molecular genetics. The completion of the human genome project and the human genome diversity project make it straightforward to ask whether variation in a particular gene correlates with variation in behavior, brain structure, brain activity, or all of the above. Strategies that unify the wealth of biochemical knowledge pertaining to synapse formation with the functional measures of brain structure and activity may lead to new insights in developmental cognitive psychology.
KW - Alleles
KW - Attention
KW - Attention Deficit Disorder with Hyperactivity
KW - Cognition Disorders
KW - DNA Mutational Analysis
KW - DNA Primers
KW - Fragile X Syndrome
KW - Humans
KW - Intellectual Disability
KW - Membrane Proteins
KW - Molecular Biology
KW - Nerve Tissue Proteins
KW - Point Mutation
KW - Polymerase Chain Reaction
KW - RGS Proteins
KW - Receptors, Dopamine D2
KW - Receptors, N-Methyl-D-Aspartate
KW - Synapses
KW - Synaptosomal-Associated Protein 25
U2 - 10.1002/mrdd.10078
DO - 10.1002/mrdd.10078
M3 - SCORING: Journal article
C2 - 12953297
VL - 9
SP - 178
EP - 183
JO - MENT RETARD DEV D R
JF - MENT RETARD DEV D R
SN - 1080-4013
IS - 3
ER -