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Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs

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Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs. / Naujokat, Hendrik; Harder, Sönke; Schulz, Lara Yasemin; Wiltfang, Jörg; Flörke, Christian; Açil, Yahya.

In: J CRANIO MAXILL SURG, Vol. 47, No. 3, 03.2019, p. 484-490.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Naujokat, H, Harder, S, Schulz, LY, Wiltfang, J, Flörke, C & Açil, Y 2019, 'Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs', J CRANIO MAXILL SURG, vol. 47, no. 3, pp. 484-490. https://doi.org/10.1016/j.jcms.2018.12.011

APA

Naujokat, H., Harder, S., Schulz, L. Y., Wiltfang, J., Flörke, C., & Açil, Y. (2019). Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs. J CRANIO MAXILL SURG, 47(3), 484-490. https://doi.org/10.1016/j.jcms.2018.12.011

Vancouver

Naujokat H, Harder S, Schulz LY, Wiltfang J, Flörke C, Açil Y. Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs. J CRANIO MAXILL SURG. 2019 Mar;47(3):484-490. https://doi.org/10.1016/j.jcms.2018.12.011

Bibtex

@article{048c74ac16c444c8aa6d1b1fd18cbdea,
title = "Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs",
abstract = "PURPOSE: Successful implant therapy is based on fast, safe, and predictable osseointegration. Several surface modifications have been introduced to improve the bone-to-implant interaction. This in vivo study evaluates the impact of plasma surface conditioning on early wound healing and osseointegration.MATERIALS AND METHODS: A total of 16 dental implants with a sand-blasted and acid-etched surface were conditioned with cold atmospheric plasma prior to insertion in the frontal bone of four miniature pigs. Sequential fluorescence labeling was administered to label bone metabolism, and after 8 weeks, bone blocks were harvested for radiological, histological, and histomorphometrical evaluation.RESULTS: The plasma conditioning had no impact on the morphology of the implant surface. The bone-to-implant contact ratio was 90.4% and 86.5%, the interthread bone density 72.5% and 63.4%, and the periimplant bone density 60.5% and 61.1%, in the plasma conditioned group and control group, respectively. Concentric bands of fluorescence enrichment indicated a chronological and homogenous mineralization of newly formed bone. No unwanted periimplant side effects were detected.CONCLUSION: The increased parameters for osseointegration in this in vivo study merit further investigation in prospective clinical trials.",
keywords = "Acid Etching, Dental, Animals, Argon, Bone Density, Dental Implantation, Endosseous, Dental Implants, Dental Prosthesis Design, Microscopy, Electron, Scanning, Microscopy, Fluorescence, Models, Animal, Osseointegration, Plasma Gases, Surface Properties, Swine, Swine, Miniature, Titanium, Wound Healing",
author = "Hendrik Naujokat and S{\"o}nke Harder and Schulz, {Lara Yasemin} and J{\"o}rg Wiltfang and Christian Fl{\"o}rke and Yahya A{\c c}il",
note = "Copyright {\textcopyright} 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.",
year = "2019",
month = mar,
doi = "10.1016/j.jcms.2018.12.011",
language = "English",
volume = "47",
pages = "484--490",
journal = "J CRANIO MAXILL SURG",
issn = "1010-5182",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Surface conditioning with cold argon plasma and its effect on the osseointegration of dental implants in miniature pigs

AU - Naujokat, Hendrik

AU - Harder, Sönke

AU - Schulz, Lara Yasemin

AU - Wiltfang, Jörg

AU - Flörke, Christian

AU - Açil, Yahya

N1 - Copyright © 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

PY - 2019/3

Y1 - 2019/3

N2 - PURPOSE: Successful implant therapy is based on fast, safe, and predictable osseointegration. Several surface modifications have been introduced to improve the bone-to-implant interaction. This in vivo study evaluates the impact of plasma surface conditioning on early wound healing and osseointegration.MATERIALS AND METHODS: A total of 16 dental implants with a sand-blasted and acid-etched surface were conditioned with cold atmospheric plasma prior to insertion in the frontal bone of four miniature pigs. Sequential fluorescence labeling was administered to label bone metabolism, and after 8 weeks, bone blocks were harvested for radiological, histological, and histomorphometrical evaluation.RESULTS: The plasma conditioning had no impact on the morphology of the implant surface. The bone-to-implant contact ratio was 90.4% and 86.5%, the interthread bone density 72.5% and 63.4%, and the periimplant bone density 60.5% and 61.1%, in the plasma conditioned group and control group, respectively. Concentric bands of fluorescence enrichment indicated a chronological and homogenous mineralization of newly formed bone. No unwanted periimplant side effects were detected.CONCLUSION: The increased parameters for osseointegration in this in vivo study merit further investigation in prospective clinical trials.

AB - PURPOSE: Successful implant therapy is based on fast, safe, and predictable osseointegration. Several surface modifications have been introduced to improve the bone-to-implant interaction. This in vivo study evaluates the impact of plasma surface conditioning on early wound healing and osseointegration.MATERIALS AND METHODS: A total of 16 dental implants with a sand-blasted and acid-etched surface were conditioned with cold atmospheric plasma prior to insertion in the frontal bone of four miniature pigs. Sequential fluorescence labeling was administered to label bone metabolism, and after 8 weeks, bone blocks were harvested for radiological, histological, and histomorphometrical evaluation.RESULTS: The plasma conditioning had no impact on the morphology of the implant surface. The bone-to-implant contact ratio was 90.4% and 86.5%, the interthread bone density 72.5% and 63.4%, and the periimplant bone density 60.5% and 61.1%, in the plasma conditioned group and control group, respectively. Concentric bands of fluorescence enrichment indicated a chronological and homogenous mineralization of newly formed bone. No unwanted periimplant side effects were detected.CONCLUSION: The increased parameters for osseointegration in this in vivo study merit further investigation in prospective clinical trials.

KW - Acid Etching, Dental

KW - Animals

KW - Argon

KW - Bone Density

KW - Dental Implantation, Endosseous

KW - Dental Implants

KW - Dental Prosthesis Design

KW - Microscopy, Electron, Scanning

KW - Microscopy, Fluorescence

KW - Models, Animal

KW - Osseointegration

KW - Plasma Gases

KW - Surface Properties

KW - Swine

KW - Swine, Miniature

KW - Titanium

KW - Wound Healing

U2 - 10.1016/j.jcms.2018.12.011

DO - 10.1016/j.jcms.2018.12.011

M3 - SCORING: Journal article

C2 - 30661927

VL - 47

SP - 484

EP - 490

JO - J CRANIO MAXILL SURG

JF - J CRANIO MAXILL SURG

SN - 1010-5182

IS - 3

ER -