Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety

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Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety. / Lambert, Martin; Naber, Dieter; Karow, Anne; Huber, Christian G; Köhler, Jürgen; Heymann, Joachim; Schimmelmann, Benno G.

In: SCHIZOPHR RES, Vol. 110, No. 1-3, 1-3, 05.2009, p. 72-79.

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@article{7c9738f060ed42eba17f22ebf244029a,
title = "Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety",
abstract = "OBJECTIVE: To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR. METHODS: 2175 patients with schizophrenia-spectrum (SZ, n=1681), schizoaffective (SA, n=249), and bipolar disorder (BPD, n=245) were treated with quetiapine over 6 months and assessed with the Clinical Global Impression-Severity of illness Scale (CGI-S) and the Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K). Diagnostic group differences and effects of mood state and anxiety on subjective wellbeing were analyzed using multi-factorial linear regression analysis and mixed models repeated measures. RESULTS: At baseline, despite similar CGI-S scores, significant SWN-K score differences between SZ (57.7 points), SA (64.1 points), and BPD (79.5 points) were detected. At baseline, depression (p",
keywords = "Adult, Affect, Analysis of Variance, Antipsychotic Agents, Anxiety, Dibenzothiazepines, Female, Humans, Male, Mental Disorders, Middle Aged, Outpatients, Prospective Studies, Psychiatric Status Rating Scales, Quetiapine Fumarate, Severity of Illness Index, Time Factors, Young Adult",
author = "Martin Lambert and Dieter Naber and Anne Karow and Huber, {Christian G} and J{\"u}rgen K{\"o}hler and Joachim Heymann and Schimmelmann, {Benno G}",
year = "2009",
month = may,
doi = "10.1016/j.schres.2009.03.004",
language = "English",
volume = "110",
pages = "72--79",
journal = "SCHIZOPHR RES",
issn = "0920-9964",
publisher = "Elsevier",
number = "1-3",

}

RIS

TY - JOUR

T1 - Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety

AU - Lambert, Martin

AU - Naber, Dieter

AU - Karow, Anne

AU - Huber, Christian G

AU - Köhler, Jürgen

AU - Heymann, Joachim

AU - Schimmelmann, Benno G

PY - 2009/5

Y1 - 2009/5

N2 - OBJECTIVE: To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR. METHODS: 2175 patients with schizophrenia-spectrum (SZ, n=1681), schizoaffective (SA, n=249), and bipolar disorder (BPD, n=245) were treated with quetiapine over 6 months and assessed with the Clinical Global Impression-Severity of illness Scale (CGI-S) and the Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K). Diagnostic group differences and effects of mood state and anxiety on subjective wellbeing were analyzed using multi-factorial linear regression analysis and mixed models repeated measures. RESULTS: At baseline, despite similar CGI-S scores, significant SWN-K score differences between SZ (57.7 points), SA (64.1 points), and BPD (79.5 points) were detected. At baseline, depression (p

AB - OBJECTIVE: To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR. METHODS: 2175 patients with schizophrenia-spectrum (SZ, n=1681), schizoaffective (SA, n=249), and bipolar disorder (BPD, n=245) were treated with quetiapine over 6 months and assessed with the Clinical Global Impression-Severity of illness Scale (CGI-S) and the Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K). Diagnostic group differences and effects of mood state and anxiety on subjective wellbeing were analyzed using multi-factorial linear regression analysis and mixed models repeated measures. RESULTS: At baseline, despite similar CGI-S scores, significant SWN-K score differences between SZ (57.7 points), SA (64.1 points), and BPD (79.5 points) were detected. At baseline, depression (p

KW - Adult

KW - Affect

KW - Analysis of Variance

KW - Antipsychotic Agents

KW - Anxiety

KW - Dibenzothiazepines

KW - Female

KW - Humans

KW - Male

KW - Mental Disorders

KW - Middle Aged

KW - Outpatients

KW - Prospective Studies

KW - Psychiatric Status Rating Scales

KW - Quetiapine Fumarate

KW - Severity of Illness Index

KW - Time Factors

KW - Young Adult

U2 - 10.1016/j.schres.2009.03.004

DO - 10.1016/j.schres.2009.03.004

M3 - SCORING: Journal article

C2 - 19321310

VL - 110

SP - 72

EP - 79

JO - SCHIZOPHR RES

JF - SCHIZOPHR RES

SN - 0920-9964

IS - 1-3

M1 - 1-3

ER -