Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety
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Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety. / Lambert, Martin; Naber, Dieter; Karow, Anne; Huber, Christian G; Köhler, Jürgen; Heymann, Joachim; Schimmelmann, Benno G.
in: SCHIZOPHR RES, Jahrgang 110, Nr. 1-3, 1-3, 05.2009, S. 72-79.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Subjective wellbeing under quetiapine treatment - effect of diagnosis, mood state, and anxiety
AU - Lambert, Martin
AU - Naber, Dieter
AU - Karow, Anne
AU - Huber, Christian G
AU - Köhler, Jürgen
AU - Heymann, Joachim
AU - Schimmelmann, Benno G
PY - 2009/5
Y1 - 2009/5
N2 - OBJECTIVE: To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR. METHODS: 2175 patients with schizophrenia-spectrum (SZ, n=1681), schizoaffective (SA, n=249), and bipolar disorder (BPD, n=245) were treated with quetiapine over 6 months and assessed with the Clinical Global Impression-Severity of illness Scale (CGI-S) and the Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K). Diagnostic group differences and effects of mood state and anxiety on subjective wellbeing were analyzed using multi-factorial linear regression analysis and mixed models repeated measures. RESULTS: At baseline, despite similar CGI-S scores, significant SWN-K score differences between SZ (57.7 points), SA (64.1 points), and BPD (79.5 points) were detected. At baseline, depression (p
AB - OBJECTIVE: To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR. METHODS: 2175 patients with schizophrenia-spectrum (SZ, n=1681), schizoaffective (SA, n=249), and bipolar disorder (BPD, n=245) were treated with quetiapine over 6 months and assessed with the Clinical Global Impression-Severity of illness Scale (CGI-S) and the Subjective Wellbeing under Neuroleptic Treatment Scale (SWN-K). Diagnostic group differences and effects of mood state and anxiety on subjective wellbeing were analyzed using multi-factorial linear regression analysis and mixed models repeated measures. RESULTS: At baseline, despite similar CGI-S scores, significant SWN-K score differences between SZ (57.7 points), SA (64.1 points), and BPD (79.5 points) were detected. At baseline, depression (p
KW - Adult
KW - Affect
KW - Analysis of Variance
KW - Antipsychotic Agents
KW - Anxiety
KW - Dibenzothiazepines
KW - Female
KW - Humans
KW - Male
KW - Mental Disorders
KW - Middle Aged
KW - Outpatients
KW - Prospective Studies
KW - Psychiatric Status Rating Scales
KW - Quetiapine Fumarate
KW - Severity of Illness Index
KW - Time Factors
KW - Young Adult
U2 - 10.1016/j.schres.2009.03.004
DO - 10.1016/j.schres.2009.03.004
M3 - SCORING: Journal article
C2 - 19321310
VL - 110
SP - 72
EP - 79
JO - SCHIZOPHR RES
JF - SCHIZOPHR RES
SN - 0920-9964
IS - 1-3
M1 - 1-3
ER -