Stability of the dexamethasone suppression test in borderline personality disorder with and without comorbid PTSD: a one-year follow-up study.

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Stability of the dexamethasone suppression test in borderline personality disorder with and without comorbid PTSD: a one-year follow-up study. / Wingenfeld, Katja; Lange, Wolfgang; Wulff, Hella; Berea, Christina; Beblo, Thomas; Saavedra, Anamaria Silva; Mensebach, Christoph; Driessen, Martin.

In: J CLIN PSYCHOL, Vol. 63, No. 9, 9, 2007, p. 843-850.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Wingenfeld, K, Lange, W, Wulff, H, Berea, C, Beblo, T, Saavedra, AS, Mensebach, C & Driessen, M 2007, 'Stability of the dexamethasone suppression test in borderline personality disorder with and without comorbid PTSD: a one-year follow-up study.', J CLIN PSYCHOL, vol. 63, no. 9, 9, pp. 843-850. <http://www.ncbi.nlm.nih.gov/pubmed/17674401?dopt=Citation>

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Bibtex

@article{0f421b29ead846ea80cae34db6da4347,
title = "Stability of the dexamethasone suppression test in borderline personality disorder with and without comorbid PTSD: a one-year follow-up study.",
abstract = "Alterations in hypothalamic-pituitary-adrenal axis feedback regulation have been repeatedly reported in patients with borderline personality disorder (BPD). Due to the cross-sectional design of these studies, little is known about the longitudinal course of HPA axis functioning. In a sample of 13 patients with BPD, the dexamethasone suppression test (DST) has been used in a one-year follow-up study. There were no changes of cortisol concentrations before or after dexamethasone intake between baseline and follow-up examination. Patients with comorbid posttraumatic stress disorder (PTSD) showed more pronounced cortisol suppression compared to those without PTSD. The DST seems to be a stable marker of alterations in HPA axis feedback regulation in BPD, which is also reflected by substantial correlations between percentage of cortisol suppression at baseline and follow-up examination.",
author = "Katja Wingenfeld and Wolfgang Lange and Hella Wulff and Christina Berea and Thomas Beblo and Saavedra, {Anamaria Silva} and Christoph Mensebach and Martin Driessen",
year = "2007",
language = "Deutsch",
volume = "63",
pages = "843--850",
journal = "J CLIN PSYCHOL",
issn = "0021-9762",
publisher = "John Wiley and Sons Inc.",
number = "9",

}

RIS

TY - JOUR

T1 - Stability of the dexamethasone suppression test in borderline personality disorder with and without comorbid PTSD: a one-year follow-up study.

AU - Wingenfeld, Katja

AU - Lange, Wolfgang

AU - Wulff, Hella

AU - Berea, Christina

AU - Beblo, Thomas

AU - Saavedra, Anamaria Silva

AU - Mensebach, Christoph

AU - Driessen, Martin

PY - 2007

Y1 - 2007

N2 - Alterations in hypothalamic-pituitary-adrenal axis feedback regulation have been repeatedly reported in patients with borderline personality disorder (BPD). Due to the cross-sectional design of these studies, little is known about the longitudinal course of HPA axis functioning. In a sample of 13 patients with BPD, the dexamethasone suppression test (DST) has been used in a one-year follow-up study. There were no changes of cortisol concentrations before or after dexamethasone intake between baseline and follow-up examination. Patients with comorbid posttraumatic stress disorder (PTSD) showed more pronounced cortisol suppression compared to those without PTSD. The DST seems to be a stable marker of alterations in HPA axis feedback regulation in BPD, which is also reflected by substantial correlations between percentage of cortisol suppression at baseline and follow-up examination.

AB - Alterations in hypothalamic-pituitary-adrenal axis feedback regulation have been repeatedly reported in patients with borderline personality disorder (BPD). Due to the cross-sectional design of these studies, little is known about the longitudinal course of HPA axis functioning. In a sample of 13 patients with BPD, the dexamethasone suppression test (DST) has been used in a one-year follow-up study. There were no changes of cortisol concentrations before or after dexamethasone intake between baseline and follow-up examination. Patients with comorbid posttraumatic stress disorder (PTSD) showed more pronounced cortisol suppression compared to those without PTSD. The DST seems to be a stable marker of alterations in HPA axis feedback regulation in BPD, which is also reflected by substantial correlations between percentage of cortisol suppression at baseline and follow-up examination.

M3 - SCORING: Zeitschriftenaufsatz

VL - 63

SP - 843

EP - 850

JO - J CLIN PSYCHOL

JF - J CLIN PSYCHOL

SN - 0021-9762

IS - 9

M1 - 9

ER -