Single gold nanorods as optical probes for spectral imaging

Frank Wackenhut; Antonio Virgilio Failla; Alfred J Meixner

doi:10.1007/s00216-015-8642-1

Single gold nanorods as optical probes for spectral imaging

Standard

Single gold nanorods as optical probes for spectral imaging. / Wackenhut, Frank; Failla, Antonio Virgilio; Meixner, Alfred J.

In: ANAL BIOANAL CHEM, Vol. 407, No. 14, 05.2015, p. 4029-4034.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Wackenhut, F, Failla, AV & Meixner, AJ 2015, 'Single gold nanorods as optical probes for spectral imaging', ANAL BIOANAL CHEM, vol. 407, no. 14, pp. 4029-4034. https://doi.org/10.1007/s00216-015-8642-1

APA

Wackenhut, F., Failla, A. V., & Meixner, A. J. (2015). Single gold nanorods as optical probes for spectral imaging. ANAL BIOANAL CHEM, 407(14), 4029-4034. https://doi.org/10.1007/s00216-015-8642-1

Vancouver

Wackenhut F, Failla AV, Meixner AJ. Single gold nanorods as optical probes for spectral imaging. ANAL BIOANAL CHEM. 2015 May;407(14):4029-4034. https://doi.org/10.1007/s00216-015-8642-1

Bibtex

@article{7b4ece04b86448b9a6b8109a0b075384,

title = "Single gold nanorods as optical probes for spectral imaging",

abstract = "In this paper, we explain in detail the wavelength dependence of the elastic scattering pattern of individual, optically isolated gold nanorods by using confocal microscopy in combination with higher order laser modes, i.e., radially/azimuthally polarized laser modes. We demonstrate that the spectral dependence of the scattering pattern is mostly caused by the relative strength of the gold nanorods' plasmonic modes at different wavelengths. Since the gold nanorods' plasmonic modes are determined by the particles' geometrical parameter, e.g., size and aspect ratio, as well as the refractive index of the surrounding medium, we show that the spectral dependence of the scattering pattern is a simple, not invasive way to determine, e.g., the gold nanorod aspect ratio or physical variation of the local environment. Thus, a further development of spectral imaging of gold nanorods can lead to the employment of this technique in biomedical assays involving also living samples.",

keywords = "Biosensing Techniques, Gold, Metal Nanoparticles, Microscopy, Confocal, Spectrum Analysis, Staining and Labeling, Journal Article, Research Support, Non-U.S. Gov't",

author = "Frank Wackenhut and Failla, {Antonio Virgilio} and Meixner, {Alfred J}",

year = "2015",

month = may,

doi = "10.1007/s00216-015-8642-1",

language = "English",

volume = "407",

pages = "4029--4034",

journal = "ANAL BIOANAL CHEM",

issn = "1618-2642",

publisher = "Springer",

number = "14",

}

RIS

TY - JOUR

T1 - Single gold nanorods as optical probes for spectral imaging

AU - Wackenhut, Frank

AU - Failla, Antonio Virgilio

AU - Meixner, Alfred J

PY - 2015/5

Y1 - 2015/5

N2 - In this paper, we explain in detail the wavelength dependence of the elastic scattering pattern of individual, optically isolated gold nanorods by using confocal microscopy in combination with higher order laser modes, i.e., radially/azimuthally polarized laser modes. We demonstrate that the spectral dependence of the scattering pattern is mostly caused by the relative strength of the gold nanorods' plasmonic modes at different wavelengths. Since the gold nanorods' plasmonic modes are determined by the particles' geometrical parameter, e.g., size and aspect ratio, as well as the refractive index of the surrounding medium, we show that the spectral dependence of the scattering pattern is a simple, not invasive way to determine, e.g., the gold nanorod aspect ratio or physical variation of the local environment. Thus, a further development of spectral imaging of gold nanorods can lead to the employment of this technique in biomedical assays involving also living samples.

AB - In this paper, we explain in detail the wavelength dependence of the elastic scattering pattern of individual, optically isolated gold nanorods by using confocal microscopy in combination with higher order laser modes, i.e., radially/azimuthally polarized laser modes. We demonstrate that the spectral dependence of the scattering pattern is mostly caused by the relative strength of the gold nanorods' plasmonic modes at different wavelengths. Since the gold nanorods' plasmonic modes are determined by the particles' geometrical parameter, e.g., size and aspect ratio, as well as the refractive index of the surrounding medium, we show that the spectral dependence of the scattering pattern is a simple, not invasive way to determine, e.g., the gold nanorod aspect ratio or physical variation of the local environment. Thus, a further development of spectral imaging of gold nanorods can lead to the employment of this technique in biomedical assays involving also living samples.

KW - Biosensing Techniques

KW - Gold

KW - Metal Nanoparticles

KW - Microscopy, Confocal

KW - Spectrum Analysis

KW - Staining and Labeling

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1007/s00216-015-8642-1

DO - 10.1007/s00216-015-8642-1

M3 - SCORING: Journal article

C2 - 25855152

VL - 407

SP - 4029

EP - 4034

JO - ANAL BIOANAL CHEM

JF - ANAL BIOANAL CHEM

SN - 1618-2642

IS - 14

ER -