Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases
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Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases. / Schneppenheim, R; Rautenberg, P; Behnke, H; Vietor, K.
In: KLIN PADIATR, Vol. 203, No. 4, 01.07.1991, p. 273-5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases
AU - Schneppenheim, R
AU - Rautenberg, P
AU - Behnke, H
AU - Vietor, K
PY - 1991/7/1
Y1 - 1991/7/1
N2 - The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither with the number of transfused blood units nor with surrogate markers for hepatitis NANB like ALT or anti HBc. Additional testing by alternate test assays revealed discordant results in 11 of these patients. Possible explanations, like reactivity to test-immanent coexpressed antigens of Saccharomyces cerevisae are discussed.
AB - The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither with the number of transfused blood units nor with surrogate markers for hepatitis NANB like ALT or anti HBc. Additional testing by alternate test assays revealed discordant results in 11 of these patients. Possible explanations, like reactivity to test-immanent coexpressed antigens of Saccharomyces cerevisae are discussed.
KW - Antineoplastic Agents
KW - Blood Transfusion
KW - Child
KW - Hepacivirus
KW - Hepatitis Antibodies
KW - Hepatitis C
KW - Humans
KW - Leukemia, Myeloid, Acute
KW - Opportunistic Infections
KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma
KW - Risk Factors
U2 - 10.1055/s-2007-1025441
DO - 10.1055/s-2007-1025441
M3 - SCORING: Journal article
C2 - 1658430
VL - 203
SP - 273
EP - 275
JO - KLIN PADIATR
JF - KLIN PADIATR
SN - 0300-8630
IS - 4
ER -