Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases

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Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases. / Schneppenheim, R; Rautenberg, P; Behnke, H; Vietor, K.

in: KLIN PADIATR, Jahrgang 203, Nr. 4, 01.07.1991, S. 273-5.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{13c6c013526d478cbe118163086dc2ea,
title = "Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases",
abstract = "The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither with the number of transfused blood units nor with surrogate markers for hepatitis NANB like ALT or anti HBc. Additional testing by alternate test assays revealed discordant results in 11 of these patients. Possible explanations, like reactivity to test-immanent coexpressed antigens of Saccharomyces cerevisae are discussed.",
keywords = "Antineoplastic Agents, Blood Transfusion, Child, Hepacivirus, Hepatitis Antibodies, Hepatitis C, Humans, Leukemia, Myeloid, Acute, Opportunistic Infections, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Risk Factors",
author = "R Schneppenheim and P Rautenberg and H Behnke and K Vietor",
year = "1991",
month = jul,
day = "1",
doi = "10.1055/s-2007-1025441",
language = "English",
volume = "203",
pages = "273--5",
journal = "KLIN PADIATR",
issn = "0300-8630",
publisher = "Georg Thieme Verlag KG",
number = "4",

}

RIS

TY - JOUR

T1 - Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases

AU - Schneppenheim, R

AU - Rautenberg, P

AU - Behnke, H

AU - Vietor, K

PY - 1991/7/1

Y1 - 1991/7/1

N2 - The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither with the number of transfused blood units nor with surrogate markers for hepatitis NANB like ALT or anti HBc. Additional testing by alternate test assays revealed discordant results in 11 of these patients. Possible explanations, like reactivity to test-immanent coexpressed antigens of Saccharomyces cerevisae are discussed.

AB - The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither with the number of transfused blood units nor with surrogate markers for hepatitis NANB like ALT or anti HBc. Additional testing by alternate test assays revealed discordant results in 11 of these patients. Possible explanations, like reactivity to test-immanent coexpressed antigens of Saccharomyces cerevisae are discussed.

KW - Antineoplastic Agents

KW - Blood Transfusion

KW - Child

KW - Hepacivirus

KW - Hepatitis Antibodies

KW - Hepatitis C

KW - Humans

KW - Leukemia, Myeloid, Acute

KW - Opportunistic Infections

KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma

KW - Risk Factors

U2 - 10.1055/s-2007-1025441

DO - 10.1055/s-2007-1025441

M3 - SCORING: Journal article

C2 - 1658430

VL - 203

SP - 273

EP - 275

JO - KLIN PADIATR

JF - KLIN PADIATR

SN - 0300-8630

IS - 4

ER -