Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5.

M Nürnberger; Ingrid Moll

Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5.

Standard

Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5. / Nürnberger, M; Moll, Ingrid.

In: DERMATOLOGY, Vol. 188, No. 4, 4, 1994, p. 296-299.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Nürnberger, M & Moll, I 1994, 'Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5.', DERMATOLOGY, vol. 188, no. 4, 4, pp. 296-299. <http://www.ncbi.nlm.nih.gov/pubmed/8193404?dopt=Citation>

APA

Nürnberger, M., & Moll, I. (1994). Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5. DERMATOLOGY, 188(4), 296-299. [4]. http://www.ncbi.nlm.nih.gov/pubmed/8193404?dopt=Citation

Vancouver

Nürnberger M, Moll I. Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5. DERMATOLOGY. 1994;188(4):296-299. 4.

Bibtex

@article{a7d360a851a447fcac7307f8ac1fd1ae,

title = "Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5.",

abstract = "Mast cells are supported to influence the growth of neurofibromas, because some of their mediators may also act as growth factors. Accordingly, mast cell stabilizers are claimed to reduce proliferation and itching of neurofibromas. Therefore, we quantified the mast cells of 19 neurofibromas and compared them with normal skin. We saw a statistically significant increase in mast cells in neurofibromas versus normal skin. However, there is no correlation between the age of neurofibromatosis (NF) patients and mast cell density. In our study the density of mast cells in neurofibromas is also independent of NF type; age of neurofibroma and chronic ultraviolet exposure in contrast to normal skin. Different tumors of the same patient had similar mast cell counts.",

author = "M N{\"u}rnberger and Ingrid Moll",

year = "1994",

language = "Deutsch",

volume = "188",

pages = "296--299",

journal = "DERMATOLOGY",

issn = "1018-8665",

publisher = "S. Karger AG",

number = "4",

}

RIS

TY - JOUR

T1 - Semiquantitative aspects of mast cells in normal skin and in neurofibromas of neurofibromatosis types 1 and 5.

AU - Nürnberger, M

AU - Moll, Ingrid

PY - 1994

Y1 - 1994

N2 - Mast cells are supported to influence the growth of neurofibromas, because some of their mediators may also act as growth factors. Accordingly, mast cell stabilizers are claimed to reduce proliferation and itching of neurofibromas. Therefore, we quantified the mast cells of 19 neurofibromas and compared them with normal skin. We saw a statistically significant increase in mast cells in neurofibromas versus normal skin. However, there is no correlation between the age of neurofibromatosis (NF) patients and mast cell density. In our study the density of mast cells in neurofibromas is also independent of NF type; age of neurofibroma and chronic ultraviolet exposure in contrast to normal skin. Different tumors of the same patient had similar mast cell counts.

AB - Mast cells are supported to influence the growth of neurofibromas, because some of their mediators may also act as growth factors. Accordingly, mast cell stabilizers are claimed to reduce proliferation and itching of neurofibromas. Therefore, we quantified the mast cells of 19 neurofibromas and compared them with normal skin. We saw a statistically significant increase in mast cells in neurofibromas versus normal skin. However, there is no correlation between the age of neurofibromatosis (NF) patients and mast cell density. In our study the density of mast cells in neurofibromas is also independent of NF type; age of neurofibroma and chronic ultraviolet exposure in contrast to normal skin. Different tumors of the same patient had similar mast cell counts.

M3 - SCORING: Zeitschriftenaufsatz

VL - 188

SP - 296

EP - 299

JO - DERMATOLOGY

JF - DERMATOLOGY

SN - 1018-8665

IS - 4

M1 - 4

ER -