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Safety of optical coherence tomography in pediatric heart transplant patients

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Safety of optical coherence tomography in pediatric heart transplant patients. / Ulrich, Sarah M; Lehner, Anja; Birnbaum, Julia; Heckel, Stefanie; Haas, Nikolaus A; Hakami, Lale; Schramm, Rene; Dalla Pozza, Robert; Fischer, Marcus; Kozlik-Feldmann, Rainer.

In: INT J CARDIOL, Vol. 228, 01.02.2017, p. 205-208.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Ulrich, SM, Lehner, A, Birnbaum, J, Heckel, S, Haas, NA, Hakami, L, Schramm, R, Dalla Pozza, R, Fischer, M & Kozlik-Feldmann, R 2017, 'Safety of optical coherence tomography in pediatric heart transplant patients', INT J CARDIOL, vol. 228, pp. 205-208. https://doi.org/10.1016/j.ijcard.2016.11.109

APA

Ulrich, S. M., Lehner, A., Birnbaum, J., Heckel, S., Haas, N. A., Hakami, L., Schramm, R., Dalla Pozza, R., Fischer, M., & Kozlik-Feldmann, R. (2017). Safety of optical coherence tomography in pediatric heart transplant patients. INT J CARDIOL, 228, 205-208. https://doi.org/10.1016/j.ijcard.2016.11.109

Vancouver

Ulrich SM, Lehner A, Birnbaum J, Heckel S, Haas NA, Hakami L et al. Safety of optical coherence tomography in pediatric heart transplant patients. INT J CARDIOL. 2017 Feb 1;228:205-208. https://doi.org/10.1016/j.ijcard.2016.11.109

Bibtex

@article{e4b5cabcfc7c4217b11caf4f1af39800,
title = "Safety of optical coherence tomography in pediatric heart transplant patients",
abstract = "BACKGROUND: Cardiac allograft vasculopathy (CAV) is a crucial problem after heart transplantation, in adults as well as in children. CAV is the main risk factor for a reduced long-term graft survival. The early diagnosis and treatment of CAV is essential for a successful long-term preservation of the donor heart. However, asymptomatic progression of CAV and concentric hyperplasia of the coronary arteries may complicate the early diagnosis by conventional measures. Intravascular imaging, such as intravascular ultrasound and optical coherence tomography (OCT), enables the diagnosis of early stage CAV. To date, there is little known about OCT in children. We present our single center experience with OCT after pediatric heart transplantation.METHODS: Retrospective analysis of OCT (n=50) after pediatric heart transplantation between June 2013 and March 2016 and comparison between angiographic appearance and OCT.RESULTS: 37 patients underwent optical coherence tomography, nine patients were examined twice and two patients tree times. The youngest patient at time of examination was 4years with a weight of 15kg (mean 50.86kg, range 15 to 88kg). There were no complications, especially no bleeding, no arrhythmias or myocardial ischemic events. Early CAV (Stanford I or II) was detected by OCT in 26 cases. Only in four of these cases, also the coronary angiography showed mild changes.CONCLUSION: OCT is a safe intravascular imaging method that can also be used in children after pediatric heart transplantation up to a minimum weight of 15kg without an increasing risk of a catheterization procedure.",
keywords = "Adolescent, Cardiac Catheterization, Child, Child, Preschool, Coronary Angiography, Coronary Artery Disease/diagnostic imaging, Female, Heart Failure/diagnostic imaging, Heart Transplantation/adverse effects, Humans, Infant, Infant, Newborn, Male, Postoperative Complications/diagnostic imaging, Retrospective Studies, Tomography, Optical Coherence",
author = "Ulrich, {Sarah M} and Anja Lehner and Julia Birnbaum and Stefanie Heckel and Haas, {Nikolaus A} and Lale Hakami and Rene Schramm and {Dalla Pozza}, Robert and Marcus Fischer and Rainer Kozlik-Feldmann",
note = "Copyright {\textcopyright} 2016 Elsevier Ireland Ltd. All rights reserved.",
year = "2017",
month = feb,
day = "1",
doi = "10.1016/j.ijcard.2016.11.109",
language = "English",
volume = "228",
pages = "205--208",
journal = "INT J CARDIOL",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Safety of optical coherence tomography in pediatric heart transplant patients

AU - Ulrich, Sarah M

AU - Lehner, Anja

AU - Birnbaum, Julia

AU - Heckel, Stefanie

AU - Haas, Nikolaus A

AU - Hakami, Lale

AU - Schramm, Rene

AU - Dalla Pozza, Robert

AU - Fischer, Marcus

AU - Kozlik-Feldmann, Rainer

N1 - Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

PY - 2017/2/1

Y1 - 2017/2/1

N2 - BACKGROUND: Cardiac allograft vasculopathy (CAV) is a crucial problem after heart transplantation, in adults as well as in children. CAV is the main risk factor for a reduced long-term graft survival. The early diagnosis and treatment of CAV is essential for a successful long-term preservation of the donor heart. However, asymptomatic progression of CAV and concentric hyperplasia of the coronary arteries may complicate the early diagnosis by conventional measures. Intravascular imaging, such as intravascular ultrasound and optical coherence tomography (OCT), enables the diagnosis of early stage CAV. To date, there is little known about OCT in children. We present our single center experience with OCT after pediatric heart transplantation.METHODS: Retrospective analysis of OCT (n=50) after pediatric heart transplantation between June 2013 and March 2016 and comparison between angiographic appearance and OCT.RESULTS: 37 patients underwent optical coherence tomography, nine patients were examined twice and two patients tree times. The youngest patient at time of examination was 4years with a weight of 15kg (mean 50.86kg, range 15 to 88kg). There were no complications, especially no bleeding, no arrhythmias or myocardial ischemic events. Early CAV (Stanford I or II) was detected by OCT in 26 cases. Only in four of these cases, also the coronary angiography showed mild changes.CONCLUSION: OCT is a safe intravascular imaging method that can also be used in children after pediatric heart transplantation up to a minimum weight of 15kg without an increasing risk of a catheterization procedure.

AB - BACKGROUND: Cardiac allograft vasculopathy (CAV) is a crucial problem after heart transplantation, in adults as well as in children. CAV is the main risk factor for a reduced long-term graft survival. The early diagnosis and treatment of CAV is essential for a successful long-term preservation of the donor heart. However, asymptomatic progression of CAV and concentric hyperplasia of the coronary arteries may complicate the early diagnosis by conventional measures. Intravascular imaging, such as intravascular ultrasound and optical coherence tomography (OCT), enables the diagnosis of early stage CAV. To date, there is little known about OCT in children. We present our single center experience with OCT after pediatric heart transplantation.METHODS: Retrospective analysis of OCT (n=50) after pediatric heart transplantation between June 2013 and March 2016 and comparison between angiographic appearance and OCT.RESULTS: 37 patients underwent optical coherence tomography, nine patients were examined twice and two patients tree times. The youngest patient at time of examination was 4years with a weight of 15kg (mean 50.86kg, range 15 to 88kg). There were no complications, especially no bleeding, no arrhythmias or myocardial ischemic events. Early CAV (Stanford I or II) was detected by OCT in 26 cases. Only in four of these cases, also the coronary angiography showed mild changes.CONCLUSION: OCT is a safe intravascular imaging method that can also be used in children after pediatric heart transplantation up to a minimum weight of 15kg without an increasing risk of a catheterization procedure.

KW - Adolescent

KW - Cardiac Catheterization

KW - Child

KW - Child, Preschool

KW - Coronary Angiography

KW - Coronary Artery Disease/diagnostic imaging

KW - Female

KW - Heart Failure/diagnostic imaging

KW - Heart Transplantation/adverse effects

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Male

KW - Postoperative Complications/diagnostic imaging

KW - Retrospective Studies

KW - Tomography, Optical Coherence

U2 - 10.1016/j.ijcard.2016.11.109

DO - 10.1016/j.ijcard.2016.11.109

M3 - SCORING: Journal article

C2 - 27866017

VL - 228

SP - 205

EP - 208

JO - INT J CARDIOL

JF - INT J CARDIOL

SN - 0167-5273

ER -