Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters

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Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters. / Macht, Stephan; Beseoglu, Kerim; Eicker, Sven; Rybacki, Konrad; Braun, Sebastian; Mathys, Christian; Antoch, Gerald; Turowski, Bernd.

In: EUR J RADIOL, Vol. 81, No. 8, 08.2012, p. 1883-5.

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@article{bc01db11b8d24afbbcd89457735c62ee,
title = "Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters",
abstract = "INTRODUCTION: CT perfusion studies play an important role in the early detection as well as in therapy monitoring of vasospasm after subarachnoid hemorrhage. High-flow injections via central venous catheters are not recommended but may sometimes be the only possibility to obtain high-quality images.MATERIALS AND METHODS: We retrospectively analyzed our data for CT perfusions performed with power injection of contrast material with an iodine concentration of 400mg/ml via the distal 16G lumen of the Arrow three and five lumen central venous catheter with preset flow rates of 5ml/s.RESULTS: 104 examinations with central venous catheters were evaluated (67 with five lumen and 37 with three lumen). No complications were observed. Mean flow rates were 4.4±0.5ml/s using the three lumen catheter and 4.6±0.6ml/s using the five lumen catheter respectively. The mean injection pressure measured by the power injector was 200.7±17.5psi for the three lumen central venous catheter and 194.5±6.5psi for the five lumen catheter, respectively.CONCLUSION: Following a strict safety protocol there were no complications associated with power injections of contrast material containing 400mg iodine/ml with preset flow rates up to 5ml/s via the distal 16G lumen of the Arrow multi-lumen central venous catheter. However, since power-injections are off-label use with Arrow central venous catheters, this procedure cannot be recommended until potential safety hazards have been ruled out by the manufacturer.",
keywords = "Brain, Catheterization, Central Venous, Central Venous Catheters, Contrast Media, Feasibility Studies, Humans, Perfusion Imaging, Retrospective Studies, Tomography, X-Ray Computed",
author = "Stephan Macht and Kerim Beseoglu and Sven Eicker and Konrad Rybacki and Sebastian Braun and Christian Mathys and Gerald Antoch and Bernd Turowski",
note = "Copyright {\textcopyright} 2011 Elsevier Ireland Ltd. All rights reserved.",
year = "2012",
month = aug,
doi = "10.1016/j.ejrad.2011.04.043",
language = "English",
volume = "81",
pages = "1883--5",
journal = "EUR J RADIOL",
issn = "0720-048X",
publisher = "Elsevier",
number = "8",

}

RIS

TY - JOUR

T1 - Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters

AU - Macht, Stephan

AU - Beseoglu, Kerim

AU - Eicker, Sven

AU - Rybacki, Konrad

AU - Braun, Sebastian

AU - Mathys, Christian

AU - Antoch, Gerald

AU - Turowski, Bernd

N1 - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

PY - 2012/8

Y1 - 2012/8

N2 - INTRODUCTION: CT perfusion studies play an important role in the early detection as well as in therapy monitoring of vasospasm after subarachnoid hemorrhage. High-flow injections via central venous catheters are not recommended but may sometimes be the only possibility to obtain high-quality images.MATERIALS AND METHODS: We retrospectively analyzed our data for CT perfusions performed with power injection of contrast material with an iodine concentration of 400mg/ml via the distal 16G lumen of the Arrow three and five lumen central venous catheter with preset flow rates of 5ml/s.RESULTS: 104 examinations with central venous catheters were evaluated (67 with five lumen and 37 with three lumen). No complications were observed. Mean flow rates were 4.4±0.5ml/s using the three lumen catheter and 4.6±0.6ml/s using the five lumen catheter respectively. The mean injection pressure measured by the power injector was 200.7±17.5psi for the three lumen central venous catheter and 194.5±6.5psi for the five lumen catheter, respectively.CONCLUSION: Following a strict safety protocol there were no complications associated with power injections of contrast material containing 400mg iodine/ml with preset flow rates up to 5ml/s via the distal 16G lumen of the Arrow multi-lumen central venous catheter. However, since power-injections are off-label use with Arrow central venous catheters, this procedure cannot be recommended until potential safety hazards have been ruled out by the manufacturer.

AB - INTRODUCTION: CT perfusion studies play an important role in the early detection as well as in therapy monitoring of vasospasm after subarachnoid hemorrhage. High-flow injections via central venous catheters are not recommended but may sometimes be the only possibility to obtain high-quality images.MATERIALS AND METHODS: We retrospectively analyzed our data for CT perfusions performed with power injection of contrast material with an iodine concentration of 400mg/ml via the distal 16G lumen of the Arrow three and five lumen central venous catheter with preset flow rates of 5ml/s.RESULTS: 104 examinations with central venous catheters were evaluated (67 with five lumen and 37 with three lumen). No complications were observed. Mean flow rates were 4.4±0.5ml/s using the three lumen catheter and 4.6±0.6ml/s using the five lumen catheter respectively. The mean injection pressure measured by the power injector was 200.7±17.5psi for the three lumen central venous catheter and 194.5±6.5psi for the five lumen catheter, respectively.CONCLUSION: Following a strict safety protocol there were no complications associated with power injections of contrast material containing 400mg iodine/ml with preset flow rates up to 5ml/s via the distal 16G lumen of the Arrow multi-lumen central venous catheter. However, since power-injections are off-label use with Arrow central venous catheters, this procedure cannot be recommended until potential safety hazards have been ruled out by the manufacturer.

KW - Brain

KW - Catheterization, Central Venous

KW - Central Venous Catheters

KW - Contrast Media

KW - Feasibility Studies

KW - Humans

KW - Perfusion Imaging

KW - Retrospective Studies

KW - Tomography, X-Ray Computed

U2 - 10.1016/j.ejrad.2011.04.043

DO - 10.1016/j.ejrad.2011.04.043

M3 - SCORING: Journal article

C2 - 21601402

VL - 81

SP - 1883

EP - 1885

JO - EUR J RADIOL

JF - EUR J RADIOL

SN - 0720-048X

IS - 8

ER -