Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters
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Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters. / Macht, Stephan; Beseoglu, Kerim; Eicker, Sven; Rybacki, Konrad; Braun, Sebastian; Mathys, Christian; Antoch, Gerald; Turowski, Bernd.
in: EUR J RADIOL, Jahrgang 81, Nr. 8, 08.2012, S. 1883-5.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters
AU - Macht, Stephan
AU - Beseoglu, Kerim
AU - Eicker, Sven
AU - Rybacki, Konrad
AU - Braun, Sebastian
AU - Mathys, Christian
AU - Antoch, Gerald
AU - Turowski, Bernd
N1 - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
PY - 2012/8
Y1 - 2012/8
N2 - INTRODUCTION: CT perfusion studies play an important role in the early detection as well as in therapy monitoring of vasospasm after subarachnoid hemorrhage. High-flow injections via central venous catheters are not recommended but may sometimes be the only possibility to obtain high-quality images.MATERIALS AND METHODS: We retrospectively analyzed our data for CT perfusions performed with power injection of contrast material with an iodine concentration of 400mg/ml via the distal 16G lumen of the Arrow three and five lumen central venous catheter with preset flow rates of 5ml/s.RESULTS: 104 examinations with central venous catheters were evaluated (67 with five lumen and 37 with three lumen). No complications were observed. Mean flow rates were 4.4±0.5ml/s using the three lumen catheter and 4.6±0.6ml/s using the five lumen catheter respectively. The mean injection pressure measured by the power injector was 200.7±17.5psi for the three lumen central venous catheter and 194.5±6.5psi for the five lumen catheter, respectively.CONCLUSION: Following a strict safety protocol there were no complications associated with power injections of contrast material containing 400mg iodine/ml with preset flow rates up to 5ml/s via the distal 16G lumen of the Arrow multi-lumen central venous catheter. However, since power-injections are off-label use with Arrow central venous catheters, this procedure cannot be recommended until potential safety hazards have been ruled out by the manufacturer.
AB - INTRODUCTION: CT perfusion studies play an important role in the early detection as well as in therapy monitoring of vasospasm after subarachnoid hemorrhage. High-flow injections via central venous catheters are not recommended but may sometimes be the only possibility to obtain high-quality images.MATERIALS AND METHODS: We retrospectively analyzed our data for CT perfusions performed with power injection of contrast material with an iodine concentration of 400mg/ml via the distal 16G lumen of the Arrow three and five lumen central venous catheter with preset flow rates of 5ml/s.RESULTS: 104 examinations with central venous catheters were evaluated (67 with five lumen and 37 with three lumen). No complications were observed. Mean flow rates were 4.4±0.5ml/s using the three lumen catheter and 4.6±0.6ml/s using the five lumen catheter respectively. The mean injection pressure measured by the power injector was 200.7±17.5psi for the three lumen central venous catheter and 194.5±6.5psi for the five lumen catheter, respectively.CONCLUSION: Following a strict safety protocol there were no complications associated with power injections of contrast material containing 400mg iodine/ml with preset flow rates up to 5ml/s via the distal 16G lumen of the Arrow multi-lumen central venous catheter. However, since power-injections are off-label use with Arrow central venous catheters, this procedure cannot be recommended until potential safety hazards have been ruled out by the manufacturer.
KW - Brain
KW - Catheterization, Central Venous
KW - Central Venous Catheters
KW - Contrast Media
KW - Feasibility Studies
KW - Humans
KW - Perfusion Imaging
KW - Retrospective Studies
KW - Tomography, X-Ray Computed
U2 - 10.1016/j.ejrad.2011.04.043
DO - 10.1016/j.ejrad.2011.04.043
M3 - SCORING: Journal article
C2 - 21601402
VL - 81
SP - 1883
EP - 1885
JO - EUR J RADIOL
JF - EUR J RADIOL
SN - 0720-048X
IS - 8
ER -