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Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes

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Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes. / Shkurnikov, M Yu; Knyazev, E N; Wicklein, D; Schumacher, U; Samatov, T R; Tonevitsky, A G.

In: B EXP BIOL MED+, Vol. 160, No. 6, 04.2016, p. 807-10.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Shkurnikov, MY, Knyazev, EN, Wicklein, D, Schumacher, U, Samatov, TR & Tonevitsky, AG 2016, 'Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes', B EXP BIOL MED+, vol. 160, no. 6, pp. 807-10. https://doi.org/10.1007/s10517-016-3315-4

APA

Shkurnikov, M. Y., Knyazev, E. N., Wicklein, D., Schumacher, U., Samatov, T. R., & Tonevitsky, A. G. (2016). Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes. B EXP BIOL MED+, 160(6), 807-10. https://doi.org/10.1007/s10517-016-3315-4

Vancouver

Shkurnikov MY, Knyazev EN, Wicklein D, Schumacher U, Samatov TR, Tonevitsky AG. Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes. B EXP BIOL MED+. 2016 Apr;160(6):807-10. https://doi.org/10.1007/s10517-016-3315-4

Bibtex

@article{381fdcb0e6254cc5a1247c7120b02dcd,
title = "Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes",
abstract = "Molecule L1CAM is specific for nerve cells and tumors of various localizations. The expression of L1CAM is significantly higher in melanoma in comparison with benign nevi and correlates with the progress of melanoma and transition from radial to vertical growth. Monoclonal antibodies to L1CAM effectively and specifically attenuate melanoma growth, though stimulates the epithelial-mesenchymal transition. shRNA-mediated knock-down of L1CAM showed the involvement of L1CAM in regulation of activity of the canonical Wnt pathway and expression of genes of class I melanoma-associated antigens (MAGE).",
author = "Shkurnikov, {M Yu} and Knyazev, {E N} and D Wicklein and U Schumacher and Samatov, {T R} and Tonevitsky, {A G}",
year = "2016",
month = apr,
doi = "10.1007/s10517-016-3315-4",
language = "English",
volume = "160",
pages = "807--10",
journal = "B EXP BIOL MED+",
issn = "0007-4888",
publisher = "Springer New York",
number = "6",

}

RIS

TY - JOUR

T1 - Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes

AU - Shkurnikov, M Yu

AU - Knyazev, E N

AU - Wicklein, D

AU - Schumacher, U

AU - Samatov, T R

AU - Tonevitsky, A G

PY - 2016/4

Y1 - 2016/4

N2 - Molecule L1CAM is specific for nerve cells and tumors of various localizations. The expression of L1CAM is significantly higher in melanoma in comparison with benign nevi and correlates with the progress of melanoma and transition from radial to vertical growth. Monoclonal antibodies to L1CAM effectively and specifically attenuate melanoma growth, though stimulates the epithelial-mesenchymal transition. shRNA-mediated knock-down of L1CAM showed the involvement of L1CAM in regulation of activity of the canonical Wnt pathway and expression of genes of class I melanoma-associated antigens (MAGE).

AB - Molecule L1CAM is specific for nerve cells and tumors of various localizations. The expression of L1CAM is significantly higher in melanoma in comparison with benign nevi and correlates with the progress of melanoma and transition from radial to vertical growth. Monoclonal antibodies to L1CAM effectively and specifically attenuate melanoma growth, though stimulates the epithelial-mesenchymal transition. shRNA-mediated knock-down of L1CAM showed the involvement of L1CAM in regulation of activity of the canonical Wnt pathway and expression of genes of class I melanoma-associated antigens (MAGE).

U2 - 10.1007/s10517-016-3315-4

DO - 10.1007/s10517-016-3315-4

M3 - SCORING: Journal article

C2 - 27165065

VL - 160

SP - 807

EP - 810

JO - B EXP BIOL MED+

JF - B EXP BIOL MED+

SN - 0007-4888

IS - 6

ER -