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Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes

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Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes. / Nikulin, S V; Raigorodskaya, M P; Poloznikov, A A; Zakharova, G S; Schumacher, U; Wicklein, D; Stürken, C; Riecken, K; Fomicheva, K A; Alekseev, B Ya; Shkurnikov, M Yu.

In: B EXP BIOL MED+, Vol. 164, No. 5, 03.2018, p. 650-654.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Nikulin, SV, Raigorodskaya, MP, Poloznikov, AA, Zakharova, GS, Schumacher, U, Wicklein, D, Stürken, C, Riecken, K, Fomicheva, KA, Alekseev, BY & Shkurnikov, MY 2018, 'Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes', B EXP BIOL MED+, vol. 164, no. 5, pp. 650-654. https://doi.org/10.1007/s10517-018-4051-8

APA

Nikulin, S. V., Raigorodskaya, M. P., Poloznikov, A. A., Zakharova, G. S., Schumacher, U., Wicklein, D., Stürken, C., Riecken, K., Fomicheva, K. A., Alekseev, B. Y., & Shkurnikov, M. Y. (2018). Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes. B EXP BIOL MED+, 164(5), 650-654. https://doi.org/10.1007/s10517-018-4051-8

Vancouver

Nikulin SV, Raigorodskaya MP, Poloznikov AA, Zakharova GS, Schumacher U, Wicklein D et al. Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes. B EXP BIOL MED+. 2018 Mar;164(5):650-654. https://doi.org/10.1007/s10517-018-4051-8

Bibtex

@article{3d0ce48982e942d5ae167c3d4f8f1a2a,
title = "Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes",
abstract = "Protein IGFBP6 plays an important role in the pathogenesis of many malignant tumors, including breast cancer. The relationship between IGFBP6 protein and the expression of genes associated with the epithelial-mesenchymal transition is studied. Gene IGFBP6 knockdown does not trigger the epithelial-mesenchymal transition in MDA-MB-231 cells, but modifies significantly the expression of many genes involved in this process. A decrease of IGFBP6 expression can involve a decrease in the expression of N-cadherin and transcription factor Slug.",
keywords = "Journal Article",
author = "Nikulin, {S V} and Raigorodskaya, {M P} and Poloznikov, {A A} and Zakharova, {G S} and U Schumacher and D Wicklein and C St{\"u}rken and K Riecken and Fomicheva, {K A} and Alekseev, {B Ya} and Shkurnikov, {M Yu}",
year = "2018",
month = mar,
doi = "10.1007/s10517-018-4051-8",
language = "English",
volume = "164",
pages = "650--654",
journal = "B EXP BIOL MED+",
issn = "0007-4888",
publisher = "Springer New York",
number = "5",

}

RIS

TY - JOUR

T1 - Role of IGFBP6 Protein in the Regulation of Epithelial-Mesenchymal Transition Genes

AU - Nikulin, S V

AU - Raigorodskaya, M P

AU - Poloznikov, A A

AU - Zakharova, G S

AU - Schumacher, U

AU - Wicklein, D

AU - Stürken, C

AU - Riecken, K

AU - Fomicheva, K A

AU - Alekseev, B Ya

AU - Shkurnikov, M Yu

PY - 2018/3

Y1 - 2018/3

N2 - Protein IGFBP6 plays an important role in the pathogenesis of many malignant tumors, including breast cancer. The relationship between IGFBP6 protein and the expression of genes associated with the epithelial-mesenchymal transition is studied. Gene IGFBP6 knockdown does not trigger the epithelial-mesenchymal transition in MDA-MB-231 cells, but modifies significantly the expression of many genes involved in this process. A decrease of IGFBP6 expression can involve a decrease in the expression of N-cadherin and transcription factor Slug.

AB - Protein IGFBP6 plays an important role in the pathogenesis of many malignant tumors, including breast cancer. The relationship between IGFBP6 protein and the expression of genes associated with the epithelial-mesenchymal transition is studied. Gene IGFBP6 knockdown does not trigger the epithelial-mesenchymal transition in MDA-MB-231 cells, but modifies significantly the expression of many genes involved in this process. A decrease of IGFBP6 expression can involve a decrease in the expression of N-cadherin and transcription factor Slug.

KW - Journal Article

U2 - 10.1007/s10517-018-4051-8

DO - 10.1007/s10517-018-4051-8

M3 - SCORING: Journal article

C2 - 29577195

VL - 164

SP - 650

EP - 654

JO - B EXP BIOL MED+

JF - B EXP BIOL MED+

SN - 0007-4888

IS - 5

ER -