Research ExplorerPublicationsRight atrium size in the general population

Right atrium size in the general population

Standard

Right atrium size in the general population. / Keller, Karsten; Sinning, Christoph; Schulz, Andreas; Jünger, Claus; Schmitt, Volker H; Hahad, Omar; Zeller, Tanja; Beutel, Manfred; Pfeiffer, Norbert; Strauch, Konstantin; Blankenberg, Stefan; Lackner, Karl J; Prochaska, Jürgen H; Schulz, Eberhard; Münzel, Thomas; Wild, Philipp S.

In: SCI REP-UK, Vol. 11, No. 1, 22523, 18.11.2021.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Keller, K, Sinning, C, Schulz, A, Jünger, C, Schmitt, VH, Hahad, O, Zeller, T, Beutel, M, Pfeiffer, N, Strauch, K, Blankenberg, S, Lackner, KJ, Prochaska, JH, Schulz, E, Münzel, T & Wild, PS 2021, 'Right atrium size in the general population', SCI REP-UK, vol. 11, no. 1, 22523. https://doi.org/10.1038/s41598-021-01968-y

APA

Keller, K., Sinning, C., Schulz, A., Jünger, C., Schmitt, V. H., Hahad, O., Zeller, T., Beutel, M., Pfeiffer, N., Strauch, K., Blankenberg, S., Lackner, K. J., Prochaska, J. H., Schulz, E., Münzel, T., & Wild, P. S. (2021). Right atrium size in the general population. SCI REP-UK, 11(1), [22523]. https://doi.org/10.1038/s41598-021-01968-y

Vancouver

Keller K, Sinning C, Schulz A, Jünger C, Schmitt VH, Hahad O et al. Right atrium size in the general population. SCI REP-UK. 2021 Nov 18;11(1). 22523. https://doi.org/10.1038/s41598-021-01968-y

Bibtex

@article{749a5b846b354fa385792592f56078a6,
title = "Right atrium size in the general population",
abstract = "Echocardiography is the most common routine cardiac imaging method. Nevertheless, only few data about sex-specific reference limits for right atrium (RA) dimensions are available. Transthoracic echocardiographic RA measurements were studied in 9511 participants of the Gutenberg-Health-Study. A reference sample of 1942 cardiovascular healthy subjects without chronic obstructive pulmonary disease was defined. We assessed RA dimensions and sex-specific reference limits were defined using the 95th percentile of the reference sample. Results showed sex-specific differences with larger RA dimensions in men that were attenuated by standardization for body-height. RA-volume was 20.2 ml/m in women (5th-95th: 12.7-30.4 ml/m) and 26.1 ml/m in men (5th-95th: 16.0-40.5 ml/m). Multivariable regressions identified body-mass-index (BMI), coronary artery disease (CAD), chronic heart failure (CHF) and atrial fibrillation (AF) as independent key correlates of RA-volume in both sexes. All-cause mortality after median follow-up-period of 10.7 (9.81/11.6) years was higher in individuals who had RA volume/height outside the 95% reference limit (HR 1.70 [95%CI 1.29-2.23], P = 0.00014)). Based on a large community-based sample, we present sex-specific reference-values for RA dimensions normalized for height. RA-volume varies with BMI, CHF, CAD and AF in both sexes. Individuals with RA-volume outside the reference limit had a 1.7-fold higher mortality than those within reference limits.",
author = "Karsten Keller and Christoph Sinning and Andreas Schulz and Claus J{\"u}nger and Schmitt, {Volker H} and Omar Hahad and Tanja Zeller and Manfred Beutel and Norbert Pfeiffer and Konstantin Strauch and Stefan Blankenberg and Lackner, {Karl J} and Prochaska, {J{\"u}rgen H} and Eberhard Schulz and Thomas M{\"u}nzel and Wild, {Philipp S}",
note = "{\textcopyright} 2021. The Author(s).",
year = "2021",
month = nov,
day = "18",
doi = "10.1038/s41598-021-01968-y",
language = "English",
volume = "11",
journal = "SCI REP-UK",
issn = "2045-2322",
publisher = "NATURE PUBLISHING GROUP",
number = "1",

}

RIS

TY - JOUR

T1 - Right atrium size in the general population

AU - Keller, Karsten

AU - Sinning, Christoph

AU - Schulz, Andreas

AU - Jünger, Claus

AU - Schmitt, Volker H

AU - Hahad, Omar

AU - Zeller, Tanja

AU - Beutel, Manfred

AU - Pfeiffer, Norbert

AU - Strauch, Konstantin

AU - Blankenberg, Stefan

AU - Lackner, Karl J

AU - Prochaska, Jürgen H

AU - Schulz, Eberhard

AU - Münzel, Thomas

AU - Wild, Philipp S

N1 - © 2021. The Author(s).

PY - 2021/11/18

Y1 - 2021/11/18

N2 - Echocardiography is the most common routine cardiac imaging method. Nevertheless, only few data about sex-specific reference limits for right atrium (RA) dimensions are available. Transthoracic echocardiographic RA measurements were studied in 9511 participants of the Gutenberg-Health-Study. A reference sample of 1942 cardiovascular healthy subjects without chronic obstructive pulmonary disease was defined. We assessed RA dimensions and sex-specific reference limits were defined using the 95th percentile of the reference sample. Results showed sex-specific differences with larger RA dimensions in men that were attenuated by standardization for body-height. RA-volume was 20.2 ml/m in women (5th-95th: 12.7-30.4 ml/m) and 26.1 ml/m in men (5th-95th: 16.0-40.5 ml/m). Multivariable regressions identified body-mass-index (BMI), coronary artery disease (CAD), chronic heart failure (CHF) and atrial fibrillation (AF) as independent key correlates of RA-volume in both sexes. All-cause mortality after median follow-up-period of 10.7 (9.81/11.6) years was higher in individuals who had RA volume/height outside the 95% reference limit (HR 1.70 [95%CI 1.29-2.23], P = 0.00014)). Based on a large community-based sample, we present sex-specific reference-values for RA dimensions normalized for height. RA-volume varies with BMI, CHF, CAD and AF in both sexes. Individuals with RA-volume outside the reference limit had a 1.7-fold higher mortality than those within reference limits.

AB - Echocardiography is the most common routine cardiac imaging method. Nevertheless, only few data about sex-specific reference limits for right atrium (RA) dimensions are available. Transthoracic echocardiographic RA measurements were studied in 9511 participants of the Gutenberg-Health-Study. A reference sample of 1942 cardiovascular healthy subjects without chronic obstructive pulmonary disease was defined. We assessed RA dimensions and sex-specific reference limits were defined using the 95th percentile of the reference sample. Results showed sex-specific differences with larger RA dimensions in men that were attenuated by standardization for body-height. RA-volume was 20.2 ml/m in women (5th-95th: 12.7-30.4 ml/m) and 26.1 ml/m in men (5th-95th: 16.0-40.5 ml/m). Multivariable regressions identified body-mass-index (BMI), coronary artery disease (CAD), chronic heart failure (CHF) and atrial fibrillation (AF) as independent key correlates of RA-volume in both sexes. All-cause mortality after median follow-up-period of 10.7 (9.81/11.6) years was higher in individuals who had RA volume/height outside the 95% reference limit (HR 1.70 [95%CI 1.29-2.23], P = 0.00014)). Based on a large community-based sample, we present sex-specific reference-values for RA dimensions normalized for height. RA-volume varies with BMI, CHF, CAD and AF in both sexes. Individuals with RA-volume outside the reference limit had a 1.7-fold higher mortality than those within reference limits.

U2 - 10.1038/s41598-021-01968-y

DO - 10.1038/s41598-021-01968-y

M3 - SCORING: Journal article

C2 - 34795353

VL - 11

JO - SCI REP-UK

JF - SCI REP-UK

SN - 2045-2322

IS - 1

M1 - 22523

ER -