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Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia

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Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia : A CMR Study. / Sohns, Jan M; Rosenberg, Christina; Zapf, Antonia; Unterberg-Buchwald, Christina; Staab, Wieland; Schuster, Andreas; Kowallick, Johannes T; Hösch, Olga; Nguyen, Thuy-Trang; Fasshauer, Martin; Paul, Thomas; Lotz, Joachim; Steinmetz, Michael.

In: PEDIATR CARDIOL, Vol. 36, No. 6, 08.2015, p. 1239-1247.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Sohns, JM, Rosenberg, C, Zapf, A, Unterberg-Buchwald, C, Staab, W, Schuster, A, Kowallick, JT, Hösch, O, Nguyen, T-T, Fasshauer, M, Paul, T, Lotz, J & Steinmetz, M 2015, 'Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia: A CMR Study', PEDIATR CARDIOL, vol. 36, no. 6, pp. 1239-1247. https://doi.org/10.1007/s00246-015-1152-2

APA

Sohns, J. M., Rosenberg, C., Zapf, A., Unterberg-Buchwald, C., Staab, W., Schuster, A., Kowallick, J. T., Hösch, O., Nguyen, T-T., Fasshauer, M., Paul, T., Lotz, J., & Steinmetz, M. (2015). Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia: A CMR Study. PEDIATR CARDIOL, 36(6), 1239-1247. https://doi.org/10.1007/s00246-015-1152-2

Vancouver

Sohns JM, Rosenberg C, Zapf A, Unterberg-Buchwald C, Staab W, Schuster A et al. Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia: A CMR Study. PEDIATR CARDIOL. 2015 Aug;36(6):1239-1247. https://doi.org/10.1007/s00246-015-1152-2

Bibtex

@article{f40a9241875e4934819961e99f68b5b2,
title = "Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia: A CMR Study",
abstract = "The aim of this study was to evaluate right atrial (RA) volume in corrected Tetralogy of Fallot (cTOF) and assess its correlation with the occurrence of supraventricular (SV) arrhythmia. Cardiac magnetic resonance imaging (CMR) and 24-h Holter were performed in n = 67 consecutive cTOF patients (age 30 ± 11.3 years). The CMR protocol included standard HASTE, SSFP cine, and blood flow measurements. Correlations between arrhythmia in ECG, heart volume, and functional parameters were investigated by negative binominal regression. Patients' characteristics (mean ± SD) included mean RA volume of 49 ± 19 ml/m(2) (HASTE sequence), mean right ventricular (RV) end-diastolic volume of 98 ± 27 ml/m(2), mean pulmonary valve regurgitation fraction (PR) of 21 ± 19 %, BMI of 25 kg/m(2), and heart rate of 75/min. Twenty-eight out of 67 patients experienced SV arrhythmia including SV couplets or bigeminus or longer non-sustained SV tachycardia (SVT) episodes. RA volume index was identified as an independent risk factor for different degrees of SV arrhythmia (SV couplets/bigeminus p < 0.001, SVT p < 0.001). Further risk factors for SV arrhythmia were male gender (p = 0.023) and decreased left ventricular (LV) ejection fraction (EF) (LV EF p < 0.001). RA volume is increased in adult patients with cTOF with larger RA volumes relating to higher incidence of SV arrhythmia. SV arrhythmia also appeared more often in male patients and those with decreased LV EF. Risk stratification according to these parameters could help to optimize early prevention and adjusted individual therapy to improve patient outcome and quality of life.",
keywords = "Adolescent, Adult, Cardiac Volume, Electrocardiography, Female, Heart Atria, Heart Rate, Heart Ventricles, Humans, Incidence, Magnetic Resonance Imaging, Male, Pulmonary Valve Insufficiency, Stroke Volume, Tachycardia, Supraventricular, Tetralogy of Fallot, Ventricular Function, Right, Young Adult, Journal Article, Research Support, Non-U.S. Gov't",
author = "Sohns, {Jan M} and Christina Rosenberg and Antonia Zapf and Christina Unterberg-Buchwald and Wieland Staab and Andreas Schuster and Kowallick, {Johannes T} and Olga H{\"o}sch and Thuy-Trang Nguyen and Martin Fasshauer and Thomas Paul and Joachim Lotz and Michael Steinmetz",
year = "2015",
month = aug,
doi = "10.1007/s00246-015-1152-2",
language = "English",
volume = "36",
pages = "1239--1247",
journal = "PEDIATR CARDIOL",
issn = "0172-0643",
publisher = "Springer New York",
number = "6",

}

RIS

TY - JOUR

T1 - Right Atrial Volume is Increased in Corrected Tetralogy of Fallot and Correlates with the Incidence of Supraventricular Arrhythmia

T2 - A CMR Study

AU - Sohns, Jan M

AU - Rosenberg, Christina

AU - Zapf, Antonia

AU - Unterberg-Buchwald, Christina

AU - Staab, Wieland

AU - Schuster, Andreas

AU - Kowallick, Johannes T

AU - Hösch, Olga

AU - Nguyen, Thuy-Trang

AU - Fasshauer, Martin

AU - Paul, Thomas

AU - Lotz, Joachim

AU - Steinmetz, Michael

PY - 2015/8

Y1 - 2015/8

N2 - The aim of this study was to evaluate right atrial (RA) volume in corrected Tetralogy of Fallot (cTOF) and assess its correlation with the occurrence of supraventricular (SV) arrhythmia. Cardiac magnetic resonance imaging (CMR) and 24-h Holter were performed in n = 67 consecutive cTOF patients (age 30 ± 11.3 years). The CMR protocol included standard HASTE, SSFP cine, and blood flow measurements. Correlations between arrhythmia in ECG, heart volume, and functional parameters were investigated by negative binominal regression. Patients' characteristics (mean ± SD) included mean RA volume of 49 ± 19 ml/m(2) (HASTE sequence), mean right ventricular (RV) end-diastolic volume of 98 ± 27 ml/m(2), mean pulmonary valve regurgitation fraction (PR) of 21 ± 19 %, BMI of 25 kg/m(2), and heart rate of 75/min. Twenty-eight out of 67 patients experienced SV arrhythmia including SV couplets or bigeminus or longer non-sustained SV tachycardia (SVT) episodes. RA volume index was identified as an independent risk factor for different degrees of SV arrhythmia (SV couplets/bigeminus p < 0.001, SVT p < 0.001). Further risk factors for SV arrhythmia were male gender (p = 0.023) and decreased left ventricular (LV) ejection fraction (EF) (LV EF p < 0.001). RA volume is increased in adult patients with cTOF with larger RA volumes relating to higher incidence of SV arrhythmia. SV arrhythmia also appeared more often in male patients and those with decreased LV EF. Risk stratification according to these parameters could help to optimize early prevention and adjusted individual therapy to improve patient outcome and quality of life.

AB - The aim of this study was to evaluate right atrial (RA) volume in corrected Tetralogy of Fallot (cTOF) and assess its correlation with the occurrence of supraventricular (SV) arrhythmia. Cardiac magnetic resonance imaging (CMR) and 24-h Holter were performed in n = 67 consecutive cTOF patients (age 30 ± 11.3 years). The CMR protocol included standard HASTE, SSFP cine, and blood flow measurements. Correlations between arrhythmia in ECG, heart volume, and functional parameters were investigated by negative binominal regression. Patients' characteristics (mean ± SD) included mean RA volume of 49 ± 19 ml/m(2) (HASTE sequence), mean right ventricular (RV) end-diastolic volume of 98 ± 27 ml/m(2), mean pulmonary valve regurgitation fraction (PR) of 21 ± 19 %, BMI of 25 kg/m(2), and heart rate of 75/min. Twenty-eight out of 67 patients experienced SV arrhythmia including SV couplets or bigeminus or longer non-sustained SV tachycardia (SVT) episodes. RA volume index was identified as an independent risk factor for different degrees of SV arrhythmia (SV couplets/bigeminus p < 0.001, SVT p < 0.001). Further risk factors for SV arrhythmia were male gender (p = 0.023) and decreased left ventricular (LV) ejection fraction (EF) (LV EF p < 0.001). RA volume is increased in adult patients with cTOF with larger RA volumes relating to higher incidence of SV arrhythmia. SV arrhythmia also appeared more often in male patients and those with decreased LV EF. Risk stratification according to these parameters could help to optimize early prevention and adjusted individual therapy to improve patient outcome and quality of life.

KW - Adolescent

KW - Adult

KW - Cardiac Volume

KW - Electrocardiography

KW - Female

KW - Heart Atria

KW - Heart Rate

KW - Heart Ventricles

KW - Humans

KW - Incidence

KW - Magnetic Resonance Imaging

KW - Male

KW - Pulmonary Valve Insufficiency

KW - Stroke Volume

KW - Tachycardia, Supraventricular

KW - Tetralogy of Fallot

KW - Ventricular Function, Right

KW - Young Adult

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1007/s00246-015-1152-2

DO - 10.1007/s00246-015-1152-2

M3 - SCORING: Journal article

C2 - 25862665

VL - 36

SP - 1239

EP - 1247

JO - PEDIATR CARDIOL

JF - PEDIATR CARDIOL

SN - 0172-0643

IS - 6

ER -