Rickettsia felis Infection in Febrile Children, Ghana

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Rickettsia felis Infection in Febrile Children, Ghana. / Sothmann, Peter; Keller, Christian; Krumkamp, Ralf; Kreuels, Benno; Aldrich, Cassandra; Sarpong, Nimako; Steierberg, Stefanie; Winter, Doris; Boahen, Kennedy Gyau; Owusu-Dabo, Ellis; May, Jürgen; Eibach, Daniel.

In: AM J TROP MED HYG, Vol. 96, No. 4, 04.2017, p. 783-785.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Sothmann, P, Keller, C, Krumkamp, R, Kreuels, B, Aldrich, C, Sarpong, N, Steierberg, S, Winter, D, Boahen, KG, Owusu-Dabo, E, May, J & Eibach, D 2017, 'Rickettsia felis Infection in Febrile Children, Ghana', AM J TROP MED HYG, vol. 96, no. 4, pp. 783-785. https://doi.org/10.4269/ajtmh.16-0754

APA

Sothmann, P., Keller, C., Krumkamp, R., Kreuels, B., Aldrich, C., Sarpong, N., Steierberg, S., Winter, D., Boahen, K. G., Owusu-Dabo, E., May, J., & Eibach, D. (2017). Rickettsia felis Infection in Febrile Children, Ghana. AM J TROP MED HYG, 96(4), 783-785. https://doi.org/10.4269/ajtmh.16-0754

Vancouver

Sothmann P, Keller C, Krumkamp R, Kreuels B, Aldrich C, Sarpong N et al. Rickettsia felis Infection in Febrile Children, Ghana. AM J TROP MED HYG. 2017 Apr;96(4):783-785. https://doi.org/10.4269/ajtmh.16-0754

Bibtex

@article{5e4cb2317a164faab66f283048caa061,
title = "Rickettsia felis Infection in Febrile Children, Ghana",
abstract = "AbstractRickettsial infections are an underrecognized cause of febrile illness in sub-Saharan Africa. To evaluate the epidemiology and clinical features of rickettsial disease in pediatric patients in Ghana, we screened blood samples from febrile children aged less than 15 years presenting to an outpatient department in Ghana's Ashanti Region for the presence of rickettsial DNA. We detectedRickettsia felisin 7/470 (1.5%) blood samples, using two independent real-time polymerase chain reactions. No otherRickettsiaspecies were found.R. feliswas detected repeatedly in one patient, and coinfection withPlasmodium falciparumwas found in 3/7 samples. Symptoms apart from fever included cough (6/7) and vomiting (4/7). None of theR. felis-positive patients reported a rash. This study is the first report onR. felisin Ghana and adds to the growing evidence for its widespread occurrence with and without malaria coinfection in sub-Saharan Africa.",
keywords = "Anti-Bacterial Agents, Antimalarials, Artemisinins, Child, Female, Ghana, Humans, Infant, Malaria, Falciparum, Male, Rickettsia Infections, Rickettsia felis, Journal Article",
author = "Peter Sothmann and Christian Keller and Ralf Krumkamp and Benno Kreuels and Cassandra Aldrich and Nimako Sarpong and Stefanie Steierberg and Doris Winter and Boahen, {Kennedy Gyau} and Ellis Owusu-Dabo and J{\"u}rgen May and Daniel Eibach",
year = "2017",
month = apr,
doi = "10.4269/ajtmh.16-0754",
language = "English",
volume = "96",
pages = "783--785",
journal = "AM J TROP MED HYG",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "4",

}

RIS

TY - JOUR

T1 - Rickettsia felis Infection in Febrile Children, Ghana

AU - Sothmann, Peter

AU - Keller, Christian

AU - Krumkamp, Ralf

AU - Kreuels, Benno

AU - Aldrich, Cassandra

AU - Sarpong, Nimako

AU - Steierberg, Stefanie

AU - Winter, Doris

AU - Boahen, Kennedy Gyau

AU - Owusu-Dabo, Ellis

AU - May, Jürgen

AU - Eibach, Daniel

PY - 2017/4

Y1 - 2017/4

N2 - AbstractRickettsial infections are an underrecognized cause of febrile illness in sub-Saharan Africa. To evaluate the epidemiology and clinical features of rickettsial disease in pediatric patients in Ghana, we screened blood samples from febrile children aged less than 15 years presenting to an outpatient department in Ghana's Ashanti Region for the presence of rickettsial DNA. We detectedRickettsia felisin 7/470 (1.5%) blood samples, using two independent real-time polymerase chain reactions. No otherRickettsiaspecies were found.R. feliswas detected repeatedly in one patient, and coinfection withPlasmodium falciparumwas found in 3/7 samples. Symptoms apart from fever included cough (6/7) and vomiting (4/7). None of theR. felis-positive patients reported a rash. This study is the first report onR. felisin Ghana and adds to the growing evidence for its widespread occurrence with and without malaria coinfection in sub-Saharan Africa.

AB - AbstractRickettsial infections are an underrecognized cause of febrile illness in sub-Saharan Africa. To evaluate the epidemiology and clinical features of rickettsial disease in pediatric patients in Ghana, we screened blood samples from febrile children aged less than 15 years presenting to an outpatient department in Ghana's Ashanti Region for the presence of rickettsial DNA. We detectedRickettsia felisin 7/470 (1.5%) blood samples, using two independent real-time polymerase chain reactions. No otherRickettsiaspecies were found.R. feliswas detected repeatedly in one patient, and coinfection withPlasmodium falciparumwas found in 3/7 samples. Symptoms apart from fever included cough (6/7) and vomiting (4/7). None of theR. felis-positive patients reported a rash. This study is the first report onR. felisin Ghana and adds to the growing evidence for its widespread occurrence with and without malaria coinfection in sub-Saharan Africa.

KW - Anti-Bacterial Agents

KW - Antimalarials

KW - Artemisinins

KW - Child

KW - Female

KW - Ghana

KW - Humans

KW - Infant

KW - Malaria, Falciparum

KW - Male

KW - Rickettsia Infections

KW - Rickettsia felis

KW - Journal Article

U2 - 10.4269/ajtmh.16-0754

DO - 10.4269/ajtmh.16-0754

M3 - SCORING: Journal article

C2 - 28115672

VL - 96

SP - 783

EP - 785

JO - AM J TROP MED HYG

JF - AM J TROP MED HYG

SN - 0002-9637

IS - 4

ER -