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Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride.

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Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride. / Lambert, Martin; Naber, Dieter; Eich, F X; Schacht, M; Linden, M; Schimmelmann, Benno Graf.

In: ACTA PSYCHIAT SCAND, Vol. 115, No. 2, 2, 2007, p. 106-113.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Lambert, M, Naber, D, Eich, FX, Schacht, M, Linden, M & Schimmelmann, BG 2007, 'Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride.', ACTA PSYCHIAT SCAND, vol. 115, no. 2, 2, pp. 106-113. <http://www.ncbi.nlm.nih.gov/pubmed/17244174?dopt=Citation>

APA

Lambert, M., Naber, D., Eich, F. X., Schacht, M., Linden, M., & Schimmelmann, B. G. (2007). Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride. ACTA PSYCHIAT SCAND, 115(2), 106-113. [2]. http://www.ncbi.nlm.nih.gov/pubmed/17244174?dopt=Citation

Vancouver

Lambert M, Naber D, Eich FX, Schacht M, Linden M, Schimmelmann BG. Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride. ACTA PSYCHIAT SCAND. 2007;115(2):106-113. 2.

Bibtex

@article{e1ac5b92ab784033969de08a46ce92d1,
title = "Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride.",
abstract = "Studies of subjective wellbeing (SW) in schizophrenia have missed to define and to assess rate and predictors of SW response (SW-res) and SW remission (SW-rem). METHOD: A total of 727 patients with schizophrenia and severely impaired SW at entry (Subjective Wellbeing under Neuroleptics Scale, short version, SWN-K, total score or =80 points. RESULTS: Seventy percent fulfilled the SW-res criterion at week 4. At week 4 and week 12 (endpoint), the SW response criterion distinguished between patients with or without later SW remission and overall symptomatic and functional response. While 39% fulfilled the SW-rem criterion at endpoint, only 9.1% without early SW-res were in SW-rem at follow-up. Regression analyses indicated that SW-res was mainly predicted by greater severity of positive symptoms at baseline and SW-rem by lower severity of negative symptoms and better social functioning, and particularly by early SW-res. CONCLUSION: Patients with a risk of SW non-remission need to be identified early with subsequent treatment adaptation according to recommendations for incomplete remission and treatment resistance in schizophrenia.",
author = "Martin Lambert and Dieter Naber and Eich, {F X} and M Schacht and M Linden and Schimmelmann, {Benno Graf}",
year = "2007",
language = "Deutsch",
volume = "115",
pages = "106--113",
journal = "ACTA PSYCHIAT SCAND",
issn = "0001-690X",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride.

AU - Lambert, Martin

AU - Naber, Dieter

AU - Eich, F X

AU - Schacht, M

AU - Linden, M

AU - Schimmelmann, Benno Graf

PY - 2007

Y1 - 2007

N2 - Studies of subjective wellbeing (SW) in schizophrenia have missed to define and to assess rate and predictors of SW response (SW-res) and SW remission (SW-rem). METHOD: A total of 727 patients with schizophrenia and severely impaired SW at entry (Subjective Wellbeing under Neuroleptics Scale, short version, SWN-K, total score or =80 points. RESULTS: Seventy percent fulfilled the SW-res criterion at week 4. At week 4 and week 12 (endpoint), the SW response criterion distinguished between patients with or without later SW remission and overall symptomatic and functional response. While 39% fulfilled the SW-rem criterion at endpoint, only 9.1% without early SW-res were in SW-rem at follow-up. Regression analyses indicated that SW-res was mainly predicted by greater severity of positive symptoms at baseline and SW-rem by lower severity of negative symptoms and better social functioning, and particularly by early SW-res. CONCLUSION: Patients with a risk of SW non-remission need to be identified early with subsequent treatment adaptation according to recommendations for incomplete remission and treatment resistance in schizophrenia.

AB - Studies of subjective wellbeing (SW) in schizophrenia have missed to define and to assess rate and predictors of SW response (SW-res) and SW remission (SW-rem). METHOD: A total of 727 patients with schizophrenia and severely impaired SW at entry (Subjective Wellbeing under Neuroleptics Scale, short version, SWN-K, total score or =80 points. RESULTS: Seventy percent fulfilled the SW-res criterion at week 4. At week 4 and week 12 (endpoint), the SW response criterion distinguished between patients with or without later SW remission and overall symptomatic and functional response. While 39% fulfilled the SW-rem criterion at endpoint, only 9.1% without early SW-res were in SW-rem at follow-up. Regression analyses indicated that SW-res was mainly predicted by greater severity of positive symptoms at baseline and SW-rem by lower severity of negative symptoms and better social functioning, and particularly by early SW-res. CONCLUSION: Patients with a risk of SW non-remission need to be identified early with subsequent treatment adaptation according to recommendations for incomplete remission and treatment resistance in schizophrenia.

M3 - SCORING: Zeitschriftenaufsatz

VL - 115

SP - 106

EP - 113

JO - ACTA PSYCHIAT SCAND

JF - ACTA PSYCHIAT SCAND

SN - 0001-690X

IS - 2

M1 - 2

ER -