Reducing Hematologic Toxicity With Short Course Postexposure Prophylaxis With Zidovudine for HIV-1 Exposed Infants With Low Transmission Risk
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Reducing Hematologic Toxicity With Short Course Postexposure Prophylaxis With Zidovudine for HIV-1 Exposed Infants With Low Transmission Risk. / Nguyen, Thi Thanh Truc; Kobbe, Robin; Schulze-Sturm, Ulf; Blohm, Martin; Hollwitz, Bettina; Hertling, Sandra; Becker, Christina; Oommen, Prasad Thomas; Laws, Hans-Jürgen; Martignoni, Franca; Ole Jensen, Björn-Erik; Olah, Karen; Schmidtke, Susanne; Kreuels, Benno; Vasconcelos, Malte Kohns; Neubert, Jennifer.
In: PEDIATR INFECT DIS J, Vol. 38, No. 7, 07.2019, p. 727-730.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Reducing Hematologic Toxicity With Short Course Postexposure Prophylaxis With Zidovudine for HIV-1 Exposed Infants With Low Transmission Risk
AU - Nguyen, Thi Thanh Truc
AU - Kobbe, Robin
AU - Schulze-Sturm, Ulf
AU - Blohm, Martin
AU - Hollwitz, Bettina
AU - Hertling, Sandra
AU - Becker, Christina
AU - Oommen, Prasad Thomas
AU - Laws, Hans-Jürgen
AU - Martignoni, Franca
AU - Ole Jensen, Björn-Erik
AU - Olah, Karen
AU - Schmidtke, Susanne
AU - Kreuels, Benno
AU - Vasconcelos, Malte Kohns
AU - Neubert, Jennifer
PY - 2019/7
Y1 - 2019/7
N2 - Using retrospectively collected data from 383 infants born to HIV-1-infected mothers receiving antiretroviral therapy, we compared transmission rates and hematologic toxicity between infants receiving 2-week (short course) versus longer duration zidovudine postexposure prophylaxis. Short course resulted in lower hematologic toxicity without evidence of increased vertical transmission risk.
AB - Using retrospectively collected data from 383 infants born to HIV-1-infected mothers receiving antiretroviral therapy, we compared transmission rates and hematologic toxicity between infants receiving 2-week (short course) versus longer duration zidovudine postexposure prophylaxis. Short course resulted in lower hematologic toxicity without evidence of increased vertical transmission risk.
U2 - 10.1097/INF.0000000000002357
DO - 10.1097/INF.0000000000002357
M3 - SCORING: Journal article
C2 - 31033907
VL - 38
SP - 727
EP - 730
JO - PEDIATR INFECT DIS J
JF - PEDIATR INFECT DIS J
SN - 0891-3668
IS - 7
ER -