Reduced synchronization in the visual cortex of cats with strabismic amblyopia

P R Roelfsema; P König; A K Engel; R Sireteanu; W Singer

Reduced synchronization in the visual cortex of cats with strabismic amblyopia

Standard

Reduced synchronization in the visual cortex of cats with strabismic amblyopia. / Roelfsema, P R; König, P; Engel, A K; Sireteanu, R; Singer, W.

In: EUR J NEUROSCI, Vol. 6, No. 11, 01.11.1994, p. 1645-55.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Roelfsema, PR, König, P, Engel, AK, Sireteanu, R & Singer, W 1994, 'Reduced synchronization in the visual cortex of cats with strabismic amblyopia', EUR J NEUROSCI, vol. 6, no. 11, pp. 1645-55.

APA

Roelfsema, P. R., König, P., Engel, A. K., Sireteanu, R., & Singer, W. (1994). Reduced synchronization in the visual cortex of cats with strabismic amblyopia. EUR J NEUROSCI, 6(11), 1645-55.

Vancouver

Roelfsema PR, König P, Engel AK, Sireteanu R, Singer W. Reduced synchronization in the visual cortex of cats with strabismic amblyopia. EUR J NEUROSCI. 1994 Nov 1;6(11):1645-55.

Bibtex

@article{9b7d03fca6ca49ed8ea85690d99d9846,

title = "Reduced synchronization in the visual cortex of cats with strabismic amblyopia",

abstract = "Synchronous firing of spatially separate neurons was studied with multi-electrode recordings in area 17 of the visual cortex of strabismic cats which had developed behaviourally verified amblyopia of the deviated eye. Responses of neurons were evoked with moving light bars or gratings of different spatial frequency. Neurons driven by the normal eye displayed stronger synchronization of their responses than neurons dominated by the amblyopic eye. These interocular differences were highly significant and particularly pronounced for grating stimuli of high spatial frequency. No interocular differences were noted with respect to the amplitudes of responses to the light bars and gratings. These results suggest reduced synchronization of population responses as a neurophysiological correlate of strabismic amblyopia and underline the importance of correlated firing of spatially separate cortical neurons for normal processing of visual information.",

keywords = "Amblyopia, Animals, Behavior, Animal, Brain Mapping, Cats, Cortical Synchronization, Electrophysiology, Functional Laterality, Oculomotor Muscles, Orientation, Photic Stimulation, Reflex, Strabismus, Visual Cortex",

author = "Roelfsema, {P R} and P K{\"o}nig and Engel, {A K} and R Sireteanu and W Singer",

year = "1994",

month = nov,

day = "1",

language = "English",

volume = "6",

pages = "1645--55",

journal = "EUR J NEUROSCI",

issn = "0953-816X",

publisher = "Wiley-Blackwell",

number = "11",

}

RIS

TY - JOUR

T1 - Reduced synchronization in the visual cortex of cats with strabismic amblyopia

AU - Roelfsema, P R

AU - König, P

AU - Engel, A K

AU - Sireteanu, R

AU - Singer, W

PY - 1994/11/1

Y1 - 1994/11/1

N2 - Synchronous firing of spatially separate neurons was studied with multi-electrode recordings in area 17 of the visual cortex of strabismic cats which had developed behaviourally verified amblyopia of the deviated eye. Responses of neurons were evoked with moving light bars or gratings of different spatial frequency. Neurons driven by the normal eye displayed stronger synchronization of their responses than neurons dominated by the amblyopic eye. These interocular differences were highly significant and particularly pronounced for grating stimuli of high spatial frequency. No interocular differences were noted with respect to the amplitudes of responses to the light bars and gratings. These results suggest reduced synchronization of population responses as a neurophysiological correlate of strabismic amblyopia and underline the importance of correlated firing of spatially separate cortical neurons for normal processing of visual information.

AB - Synchronous firing of spatially separate neurons was studied with multi-electrode recordings in area 17 of the visual cortex of strabismic cats which had developed behaviourally verified amblyopia of the deviated eye. Responses of neurons were evoked with moving light bars or gratings of different spatial frequency. Neurons driven by the normal eye displayed stronger synchronization of their responses than neurons dominated by the amblyopic eye. These interocular differences were highly significant and particularly pronounced for grating stimuli of high spatial frequency. No interocular differences were noted with respect to the amplitudes of responses to the light bars and gratings. These results suggest reduced synchronization of population responses as a neurophysiological correlate of strabismic amblyopia and underline the importance of correlated firing of spatially separate cortical neurons for normal processing of visual information.

KW - Amblyopia

KW - Animals

KW - Behavior, Animal

KW - Brain Mapping

KW - Cats

KW - Cortical Synchronization

KW - Electrophysiology

KW - Functional Laterality

KW - Oculomotor Muscles

KW - Orientation

KW - Photic Stimulation

KW - Reflex

KW - Strabismus

KW - Visual Cortex

M3 - SCORING: Journal article

C2 - 7874303

VL - 6

SP - 1645

EP - 1655

JO - EUR J NEUROSCI

JF - EUR J NEUROSCI

SN - 0953-816X

IS - 11

ER -