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Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies

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Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies. / Heeger, Christian-Hendrik; Rexha, Enida; Maack, Sabrina; Rottner, Laura; Fink, Thomas; Mathew, Shibu; Maurer, Tilman; Lemeš, Christine; Rillig, Andreas; Wohlmuth, Peter; Reissmann, Bruno; Tilz, Roland Richard; Ouyang, Feifan; Kuck, Karl-Heinz; Metzner, Andreas.

In: CIRC J, Vol. 84, No. 6, 25.05.2020, p. 902-910.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Heeger, C-H, Rexha, E, Maack, S, Rottner, L, Fink, T, Mathew, S, Maurer, T, Lemeš, C, Rillig, A, Wohlmuth, P, Reissmann, B, Tilz, RR, Ouyang, F, Kuck, K-H & Metzner, A 2020, 'Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies', CIRC J, vol. 84, no. 6, pp. 902-910. https://doi.org/10.1253/circj.CJ-19-1144

APA

Heeger, C-H., Rexha, E., Maack, S., Rottner, L., Fink, T., Mathew, S., Maurer, T., Lemeš, C., Rillig, A., Wohlmuth, P., Reissmann, B., Tilz, R. R., Ouyang, F., Kuck, K-H., & Metzner, A. (2020). Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies. CIRC J, 84(6), 902-910. https://doi.org/10.1253/circj.CJ-19-1144

Vancouver

Heeger C-H, Rexha E, Maack S, Rottner L, Fink T, Mathew S et al. Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies. CIRC J. 2020 May 25;84(6):902-910. https://doi.org/10.1253/circj.CJ-19-1144

Bibtex

@article{da7c1419f07c4eb2bc9e04cb78b5df7e,
title = "Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies",
abstract = "BACKGROUND: The second-generation cryoballoon (CB2) has demonstrated high procedural efficacy and convincing clinical success rates for pulmonary vein isolation (PVI). Nevertheless, data on the impact of different ablations protocols on durability are limited. The aim was to comparing the durability of PVI following 3 different ablation strategies in patients with recurrence of atrial fibrillation or atrial tachycardia undergoing repeat procedures.Methods and Results:In 192 patients, a total of 751 PVs were identified. All PVs were successfully isolated during index PVI. Thirty-one out of 192 (16%) patients were treated with a bonus-freeze protocol (group 1), 67/192 (35%) patients with a no bonus-freeze protocol (group 2), and 94/192 (49%) patients with a time-to-effect-guided protocol (group 3). Persistent PVI was documented in 419/751 (55.8%) PVs, and in 41/192 (21%) patients, all PVs were persistently isolated. The total rate of PV reconnection was not significantly different between the groups (P=0.134) and the comparison of individual PVs revealed no differences (P-values for RSPV: 0.424, RIPV: 0.541, LSPV: 0.788, LIPV: 0.346, LCPV: 0.865). The procedure times were significantly reduced by omitting the bonus-freeze and applying individualized application times (group 1: 123.4±31.5 min, group 2: 112.9±39.8 min, group 3: 86.67±28.4 min, P<0.001).CONCLUSIONS: Comparing 3 common ablation protocols, no differences for durable PVI were detected. Procedure times were significantly reduced by omitting the bonus-freeze cycle and by applying individualized application times.",
keywords = "Action Potentials, Aged, Atrial Fibrillation/diagnosis, Cryosurgery/adverse effects, Female, Germany, Heart Rate, Humans, Male, Middle Aged, Operative Time, Pulmonary Veins/physiopathology, Recurrence, Retrospective Studies, Risk Factors, Tachycardia, Supraventricular/etiology, Time Factors, Treatment Outcome",
author = "Christian-Hendrik Heeger and Enida Rexha and Sabrina Maack and Laura Rottner and Thomas Fink and Shibu Mathew and Tilman Maurer and Christine Leme{\v s} and Andreas Rillig and Peter Wohlmuth and Bruno Reissmann and Tilz, {Roland Richard} and Feifan Ouyang and Karl-Heinz Kuck and Andreas Metzner",
year = "2020",
month = may,
day = "25",
doi = "10.1253/circj.CJ-19-1144",
language = "English",
volume = "84",
pages = "902--910",
journal = "CIRC J",
issn = "1346-9843",
publisher = "Japanese Circulation Society",
number = "6",

}

RIS

TY - JOUR

T1 - Reconduction After Second-Generation Cryoballoon-Based Pulmonary Vein Isolation　- Impact of Different Ablation Strategies

AU - Heeger, Christian-Hendrik

AU - Rexha, Enida

AU - Maack, Sabrina

AU - Rottner, Laura

AU - Fink, Thomas

AU - Mathew, Shibu

AU - Maurer, Tilman

AU - Lemeš, Christine

AU - Rillig, Andreas

AU - Wohlmuth, Peter

AU - Reissmann, Bruno

AU - Tilz, Roland Richard

AU - Ouyang, Feifan

AU - Kuck, Karl-Heinz

AU - Metzner, Andreas

PY - 2020/5/25

Y1 - 2020/5/25

N2 - BACKGROUND: The second-generation cryoballoon (CB2) has demonstrated high procedural efficacy and convincing clinical success rates for pulmonary vein isolation (PVI). Nevertheless, data on the impact of different ablations protocols on durability are limited. The aim was to comparing the durability of PVI following 3 different ablation strategies in patients with recurrence of atrial fibrillation or atrial tachycardia undergoing repeat procedures.Methods and Results:In 192 patients, a total of 751 PVs were identified. All PVs were successfully isolated during index PVI. Thirty-one out of 192 (16%) patients were treated with a bonus-freeze protocol (group 1), 67/192 (35%) patients with a no bonus-freeze protocol (group 2), and 94/192 (49%) patients with a time-to-effect-guided protocol (group 3). Persistent PVI was documented in 419/751 (55.8%) PVs, and in 41/192 (21%) patients, all PVs were persistently isolated. The total rate of PV reconnection was not significantly different between the groups (P=0.134) and the comparison of individual PVs revealed no differences (P-values for RSPV: 0.424, RIPV: 0.541, LSPV: 0.788, LIPV: 0.346, LCPV: 0.865). The procedure times were significantly reduced by omitting the bonus-freeze and applying individualized application times (group 1: 123.4±31.5 min, group 2: 112.9±39.8 min, group 3: 86.67±28.4 min, P<0.001).CONCLUSIONS: Comparing 3 common ablation protocols, no differences for durable PVI were detected. Procedure times were significantly reduced by omitting the bonus-freeze cycle and by applying individualized application times.

AB - BACKGROUND: The second-generation cryoballoon (CB2) has demonstrated high procedural efficacy and convincing clinical success rates for pulmonary vein isolation (PVI). Nevertheless, data on the impact of different ablations protocols on durability are limited. The aim was to comparing the durability of PVI following 3 different ablation strategies in patients with recurrence of atrial fibrillation or atrial tachycardia undergoing repeat procedures.Methods and Results:In 192 patients, a total of 751 PVs were identified. All PVs were successfully isolated during index PVI. Thirty-one out of 192 (16%) patients were treated with a bonus-freeze protocol (group 1), 67/192 (35%) patients with a no bonus-freeze protocol (group 2), and 94/192 (49%) patients with a time-to-effect-guided protocol (group 3). Persistent PVI was documented in 419/751 (55.8%) PVs, and in 41/192 (21%) patients, all PVs were persistently isolated. The total rate of PV reconnection was not significantly different between the groups (P=0.134) and the comparison of individual PVs revealed no differences (P-values for RSPV: 0.424, RIPV: 0.541, LSPV: 0.788, LIPV: 0.346, LCPV: 0.865). The procedure times were significantly reduced by omitting the bonus-freeze and applying individualized application times (group 1: 123.4±31.5 min, group 2: 112.9±39.8 min, group 3: 86.67±28.4 min, P<0.001).CONCLUSIONS: Comparing 3 common ablation protocols, no differences for durable PVI were detected. Procedure times were significantly reduced by omitting the bonus-freeze cycle and by applying individualized application times.

KW - Action Potentials

KW - Aged

KW - Atrial Fibrillation/diagnosis

KW - Cryosurgery/adverse effects

KW - Female

KW - Germany

KW - Heart Rate

KW - Humans

KW - Male

KW - Middle Aged

KW - Operative Time

KW - Pulmonary Veins/physiopathology

KW - Recurrence

KW - Retrospective Studies

KW - Risk Factors

KW - Tachycardia, Supraventricular/etiology

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1253/circj.CJ-19-1144

DO - 10.1253/circj.CJ-19-1144

M3 - SCORING: Journal article

C2 - 32307357

VL - 84

SP - 902

EP - 910

JO - CIRC J

JF - CIRC J

SN - 1346-9843

IS - 6

ER -