Recent Updates on Marine Cancer-Preventive Compounds

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Recent Updates on Marine Cancer-Preventive Compounds. / Dyshlovoy, Sergey A.

In: MAR DRUGS, Vol. 19, No. 10, 558, 29.09.2021.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{a5dd58c781d74ea48c5ee1acc3c679bd,
title = "Recent Updates on Marine Cancer-Preventive Compounds",
abstract = "The natural compounds derived from marine organisms often exhibit unique chemical structures and potent biological activities. Cancer-preventive activity is one of the rather new activities that has emerged and been extensively studied over the last decades. This review summarizes the recent updates on the marine chemopreventive compounds covering the relevant literature published in 2013-2021 and following the previous comprehensive review by Stonik and Fedorov (Marine Drugs 2014, 12, 636-671). In the current article, only the molecules having an effect on malignant transformation (or related pathway and molecules), cancer stem cells, or carcinogen-induced in vivo tumor development were considered to be {"}true{"} cancer-preventive compounds and were, therefore, reviewed. Additionally, particular attention has been given to the molecular mechanisms of chemoprevention, executed by the reported marine compounds.",
keywords = "Animals, Antineoplastic Agents, Aquatic Organisms, Biological Products, Chemoprevention",
author = "Dyshlovoy, {Sergey A}",
year = "2021",
month = sep,
day = "29",
doi = "10.3390/md19100558",
language = "English",
volume = "19",
journal = "MAR DRUGS",
issn = "1660-3397",
publisher = "MDPI AG",
number = "10",

}

RIS

TY - JOUR

T1 - Recent Updates on Marine Cancer-Preventive Compounds

AU - Dyshlovoy, Sergey A

PY - 2021/9/29

Y1 - 2021/9/29

N2 - The natural compounds derived from marine organisms often exhibit unique chemical structures and potent biological activities. Cancer-preventive activity is one of the rather new activities that has emerged and been extensively studied over the last decades. This review summarizes the recent updates on the marine chemopreventive compounds covering the relevant literature published in 2013-2021 and following the previous comprehensive review by Stonik and Fedorov (Marine Drugs 2014, 12, 636-671). In the current article, only the molecules having an effect on malignant transformation (or related pathway and molecules), cancer stem cells, or carcinogen-induced in vivo tumor development were considered to be "true" cancer-preventive compounds and were, therefore, reviewed. Additionally, particular attention has been given to the molecular mechanisms of chemoprevention, executed by the reported marine compounds.

AB - The natural compounds derived from marine organisms often exhibit unique chemical structures and potent biological activities. Cancer-preventive activity is one of the rather new activities that has emerged and been extensively studied over the last decades. This review summarizes the recent updates on the marine chemopreventive compounds covering the relevant literature published in 2013-2021 and following the previous comprehensive review by Stonik and Fedorov (Marine Drugs 2014, 12, 636-671). In the current article, only the molecules having an effect on malignant transformation (or related pathway and molecules), cancer stem cells, or carcinogen-induced in vivo tumor development were considered to be "true" cancer-preventive compounds and were, therefore, reviewed. Additionally, particular attention has been given to the molecular mechanisms of chemoprevention, executed by the reported marine compounds.

KW - Animals

KW - Antineoplastic Agents

KW - Aquatic Organisms

KW - Biological Products

KW - Chemoprevention

U2 - 10.3390/md19100558

DO - 10.3390/md19100558

M3 - SCORING: Review article

C2 - 34677457

VL - 19

JO - MAR DRUGS

JF - MAR DRUGS

SN - 1660-3397

IS - 10

M1 - 558

ER -