Recent Updates on Marine Cancer-Preventive Compounds
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Recent Updates on Marine Cancer-Preventive Compounds. / Dyshlovoy, Sergey A.
in: MAR DRUGS, Jahrgang 19, Nr. 10, 558, 29.09.2021.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Recent Updates on Marine Cancer-Preventive Compounds
AU - Dyshlovoy, Sergey A
PY - 2021/9/29
Y1 - 2021/9/29
N2 - The natural compounds derived from marine organisms often exhibit unique chemical structures and potent biological activities. Cancer-preventive activity is one of the rather new activities that has emerged and been extensively studied over the last decades. This review summarizes the recent updates on the marine chemopreventive compounds covering the relevant literature published in 2013-2021 and following the previous comprehensive review by Stonik and Fedorov (Marine Drugs 2014, 12, 636-671). In the current article, only the molecules having an effect on malignant transformation (or related pathway and molecules), cancer stem cells, or carcinogen-induced in vivo tumor development were considered to be "true" cancer-preventive compounds and were, therefore, reviewed. Additionally, particular attention has been given to the molecular mechanisms of chemoprevention, executed by the reported marine compounds.
AB - The natural compounds derived from marine organisms often exhibit unique chemical structures and potent biological activities. Cancer-preventive activity is one of the rather new activities that has emerged and been extensively studied over the last decades. This review summarizes the recent updates on the marine chemopreventive compounds covering the relevant literature published in 2013-2021 and following the previous comprehensive review by Stonik and Fedorov (Marine Drugs 2014, 12, 636-671). In the current article, only the molecules having an effect on malignant transformation (or related pathway and molecules), cancer stem cells, or carcinogen-induced in vivo tumor development were considered to be "true" cancer-preventive compounds and were, therefore, reviewed. Additionally, particular attention has been given to the molecular mechanisms of chemoprevention, executed by the reported marine compounds.
KW - Animals
KW - Antineoplastic Agents
KW - Aquatic Organisms
KW - Biological Products
KW - Chemoprevention
U2 - 10.3390/md19100558
DO - 10.3390/md19100558
M3 - SCORING: Review article
C2 - 34677457
VL - 19
JO - MAR DRUGS
JF - MAR DRUGS
SN - 1660-3397
IS - 10
M1 - 558
ER -