Quality of life in adult patients with haemophilia--a single centre experience from Sweden.

TY - JOUR

T1 - Quality of life in adult patients with haemophilia--a single centre experience from Sweden.

AU - Lindvall, K

AU - Mackensen von, Sylvia

AU - Berntorp, E

PY - 2012

Y1 - 2012

N2 - Increased or maintained health and quality of life (HRQoL) are essential goals in health care among patients with a chronic disease. To gain an understanding of HRQoL in patients with haemophilia at the Haemophilia Treatment Centre in Malmö, Sweden, patients seen from 2004-2008 were asked to complete the Short form Health Survey, SF-36, also answering to what extent haemophilia, physically and mentally, interferes with their daily life at their annual check-up. Data were extracted from the UMAS Haemophilia Database. Interference of haemophilia in daily life was estimated using a Visual Analogue Scale. A total of 105/144 haemophilia patients were included in the study (73%); 28 mildly, 21 moderately and 56 severely affected. The median age of patients at study entry was 44.0 years (range 18-84 years). The comparison of SF-36 data of Swedish haemophilia patients with the general Swedish male population yielded no significant differences in age groups 15-24, 25-34 and 65-74 years. Patients in age groups 35-44 years, 45-54 years and 55-64 years were significantly impaired in some of their HRQoL domains. For severely affected patients who filled in SF-36 over a period of 5 years no statistical differences in HRQoL were found. For patients undergoing orthopaedic surgery HRQoL increased in most SF-36 domains. Patients reported in general on the VAS that they feel 'somehow' interfered in their daily life due to haemophilia. The results indicate a need for continuous monitoring of HRQoL to identify an increased need of care in the ageing haemophilia population.

AB - Increased or maintained health and quality of life (HRQoL) are essential goals in health care among patients with a chronic disease. To gain an understanding of HRQoL in patients with haemophilia at the Haemophilia Treatment Centre in Malmö, Sweden, patients seen from 2004-2008 were asked to complete the Short form Health Survey, SF-36, also answering to what extent haemophilia, physically and mentally, interferes with their daily life at their annual check-up. Data were extracted from the UMAS Haemophilia Database. Interference of haemophilia in daily life was estimated using a Visual Analogue Scale. A total of 105/144 haemophilia patients were included in the study (73%); 28 mildly, 21 moderately and 56 severely affected. The median age of patients at study entry was 44.0 years (range 18-84 years). The comparison of SF-36 data of Swedish haemophilia patients with the general Swedish male population yielded no significant differences in age groups 15-24, 25-34 and 65-74 years. Patients in age groups 35-44 years, 45-54 years and 55-64 years were significantly impaired in some of their HRQoL domains. For severely affected patients who filled in SF-36 over a period of 5 years no statistical differences in HRQoL were found. For patients undergoing orthopaedic surgery HRQoL increased in most SF-36 domains. Patients reported in general on the VAS that they feel 'somehow' interfered in their daily life due to haemophilia. The results indicate a need for continuous monitoring of HRQoL to identify an increased need of care in the ageing haemophilia population.

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Aged, 80 and over

KW - Adolescent

KW - Questionnaires

KW - Young Adult

KW - Health Status

KW - Longitudinal Studies

KW - Quality of Life

KW - Hemophilia A/psychology

KW - Sweden

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Aged, 80 and over

KW - Adolescent

KW - Questionnaires

KW - Young Adult

KW - Health Status

KW - Longitudinal Studies

KW - Quality of Life

KW - Hemophilia A/psychology

KW - Sweden

M3 - SCORING: Journal article

VL - 18

SP - 527

EP - 531

JO - HAEMOPHILIA

JF - HAEMOPHILIA

SN - 1351-8216

IS - 4

M1 - 4

ER -