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Quality control of inclusion bodies in Escherichia coli.

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Quality control of inclusion bodies in Escherichia coli. / Jürgen, Britta; Breitenstein, Antje; Urlacher, Vlada; Büttner, Knut; Lin, Hongying; Hecker, Michael; Schweder, Thomas; Neubauer, Peter.

In: MICROB CELL FACT, Vol. 9, 2010, p. 41.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Jürgen, B, Breitenstein, A, Urlacher, V, Büttner, K, Lin, H, Hecker, M, Schweder, T & Neubauer, P 2010, 'Quality control of inclusion bodies in Escherichia coli.', MICROB CELL FACT, vol. 9, pp. 41. https://doi.org/10.1186/1475-2859-9-41

APA

Jürgen, B., Breitenstein, A., Urlacher, V., Büttner, K., Lin, H., Hecker, M., Schweder, T., & Neubauer, P. (2010). Quality control of inclusion bodies in Escherichia coli. MICROB CELL FACT, 9, 41. https://doi.org/10.1186/1475-2859-9-41

Vancouver

Jürgen B, Breitenstein A, Urlacher V, Büttner K, Lin H, Hecker M et al. Quality control of inclusion bodies in Escherichia coli. MICROB CELL FACT. 2010;9:41. https://doi.org/10.1186/1475-2859-9-41

Bibtex

@article{1c66cf2fffae43008f90ea5d8c122de8,
title = "Quality control of inclusion bodies in Escherichia coli.",
abstract = "Bacterial inclusion bodies (IBs) are key intermediates for protein production. Their quality affects the refolding yield and further purification. Recent functional and structural studies have revealed that IBs are not dead-end aggregates but undergo dynamic changes, including aggregation, refunctionalization of the protein and proteolysis. Both, aggregation of the folding intermediates and turnover of IBs are influenced by the cellular situation and a number of well-studied chaperones and proteases are included. IBs mostly contain only minor impurities and are relatively homogenous.",
author = "Britta J{\"u}rgen and Antje Breitenstein and Vlada Urlacher and Knut B{\"u}ttner and Hongying Lin and Michael Hecker and Thomas Schweder and Peter Neubauer",
year = "2010",
doi = "10.1186/1475-2859-9-41",
language = "Deutsch",
volume = "9",
pages = "41",
journal = "MICROB CELL FACT",
issn = "1475-2859",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Quality control of inclusion bodies in Escherichia coli.

AU - Jürgen, Britta

AU - Breitenstein, Antje

AU - Urlacher, Vlada

AU - Büttner, Knut

AU - Lin, Hongying

AU - Hecker, Michael

AU - Schweder, Thomas

AU - Neubauer, Peter

PY - 2010

Y1 - 2010

N2 - Bacterial inclusion bodies (IBs) are key intermediates for protein production. Their quality affects the refolding yield and further purification. Recent functional and structural studies have revealed that IBs are not dead-end aggregates but undergo dynamic changes, including aggregation, refunctionalization of the protein and proteolysis. Both, aggregation of the folding intermediates and turnover of IBs are influenced by the cellular situation and a number of well-studied chaperones and proteases are included. IBs mostly contain only minor impurities and are relatively homogenous.

AB - Bacterial inclusion bodies (IBs) are key intermediates for protein production. Their quality affects the refolding yield and further purification. Recent functional and structural studies have revealed that IBs are not dead-end aggregates but undergo dynamic changes, including aggregation, refunctionalization of the protein and proteolysis. Both, aggregation of the folding intermediates and turnover of IBs are influenced by the cellular situation and a number of well-studied chaperones and proteases are included. IBs mostly contain only minor impurities and are relatively homogenous.

U2 - 10.1186/1475-2859-9-41

DO - 10.1186/1475-2859-9-41

M3 - SCORING: Zeitschriftenaufsatz

VL - 9

SP - 41

JO - MICROB CELL FACT

JF - MICROB CELL FACT

SN - 1475-2859

ER -