Research ExplorerPublicationsPsychoneuroendocrine stress response may impair neutrophil f...

Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome.

Standard

Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome. / Kaufmann, Ines; Eisner, Christoph; Richter, Hans Peter; Huge, Volker; Beyer, Antje; Chouker, Alexander; Schelling, Gustav; Thiel, Manfred.

In: CLIN IMMUNOL, Vol. 125, No. 1, 1, 2007, p. 103-111.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Kaufmann, I, Eisner, C, Richter, HP, Huge, V, Beyer, A, Chouker, A, Schelling, G & Thiel, M 2007, 'Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome.', CLIN IMMUNOL, vol. 125, no. 1, 1, pp. 103-111. <http://www.ncbi.nlm.nih.gov/pubmed/17702656?dopt=Citation>

APA

Kaufmann, I., Eisner, C., Richter, H. P., Huge, V., Beyer, A., Chouker, A., Schelling, G., & Thiel, M. (2007). Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome. CLIN IMMUNOL, 125(1), 103-111. [1]. http://www.ncbi.nlm.nih.gov/pubmed/17702656?dopt=Citation

Vancouver

Kaufmann I, Eisner C, Richter HP, Huge V, Beyer A, Chouker A et al. Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome. CLIN IMMUNOL. 2007;125(1):103-111. 1.

Bibtex

@article{2cf855631020491f84dd9a85a8b5ba88,
title = "Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome.",
abstract = "In order to elucidate the interaction between pain, stress and innate immunity in complex regional pain syndrome (CRPS), we assessed pain and stress levels in CRPS patients and compared ex vivo functions of neutrophils between patients with CRPS and healthy volunteers. As compared with healthy volunteers, the following major alterations in CRPS patients were found: (I) elevated stress score (PTSS-10) and stress hormone concentrations, (II) decreased expression of the CD62L and CD11b/CD18 on neutrophils, (III) impaired ability of autologous plasma to enhance the capability of neutrophils to phagocytose zymosan particles, and (IV) a negative correlation between PTSS-10 values and autologous plasma enhanced phagocytosis. In vitro incubation of neutrophils with catecholamines decreased phagocytosis of zymosan. In conclusion, CRPS patients exhibit signs of impaired innate immunity which might reflect the immunological consequence of an immunosuppressive neuroendocrine stress response.",
author = "Ines Kaufmann and Christoph Eisner and Richter, {Hans Peter} and Volker Huge and Antje Beyer and Alexander Chouker and Gustav Schelling and Manfred Thiel",
year = "2007",
language = "Deutsch",
volume = "125",
pages = "103--111",
journal = "CLIN IMMUNOL",
issn = "1521-6616",
publisher = "Academic Press Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndrome.

AU - Kaufmann, Ines

AU - Eisner, Christoph

AU - Richter, Hans Peter

AU - Huge, Volker

AU - Beyer, Antje

AU - Chouker, Alexander

AU - Schelling, Gustav

AU - Thiel, Manfred

PY - 2007

Y1 - 2007

N2 - In order to elucidate the interaction between pain, stress and innate immunity in complex regional pain syndrome (CRPS), we assessed pain and stress levels in CRPS patients and compared ex vivo functions of neutrophils between patients with CRPS and healthy volunteers. As compared with healthy volunteers, the following major alterations in CRPS patients were found: (I) elevated stress score (PTSS-10) and stress hormone concentrations, (II) decreased expression of the CD62L and CD11b/CD18 on neutrophils, (III) impaired ability of autologous plasma to enhance the capability of neutrophils to phagocytose zymosan particles, and (IV) a negative correlation between PTSS-10 values and autologous plasma enhanced phagocytosis. In vitro incubation of neutrophils with catecholamines decreased phagocytosis of zymosan. In conclusion, CRPS patients exhibit signs of impaired innate immunity which might reflect the immunological consequence of an immunosuppressive neuroendocrine stress response.

AB - In order to elucidate the interaction between pain, stress and innate immunity in complex regional pain syndrome (CRPS), we assessed pain and stress levels in CRPS patients and compared ex vivo functions of neutrophils between patients with CRPS and healthy volunteers. As compared with healthy volunteers, the following major alterations in CRPS patients were found: (I) elevated stress score (PTSS-10) and stress hormone concentrations, (II) decreased expression of the CD62L and CD11b/CD18 on neutrophils, (III) impaired ability of autologous plasma to enhance the capability of neutrophils to phagocytose zymosan particles, and (IV) a negative correlation between PTSS-10 values and autologous plasma enhanced phagocytosis. In vitro incubation of neutrophils with catecholamines decreased phagocytosis of zymosan. In conclusion, CRPS patients exhibit signs of impaired innate immunity which might reflect the immunological consequence of an immunosuppressive neuroendocrine stress response.

M3 - SCORING: Zeitschriftenaufsatz

VL - 125

SP - 103

EP - 111

JO - CLIN IMMUNOL

JF - CLIN IMMUNOL

SN - 1521-6616

IS - 1

M1 - 1

ER -