Research ExplorerPublicationsProcedural success, safety and patients satisfaction after s...

Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry

Standard

Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry. / Fink, Thomas; Metzner, Andreas; Willems, Stephan; Eckardt, Lars; Ince, Hüseyin; Brachmann, Johannes; Spitzer, Stefan G; Deneke, Thomas; Schmitt, Claus; Hochadel, Matthias; Senges, Jochen; Rillig, Andreas.

In: CLIN RES CARDIOL, Vol. 108, No. 12, 12.2019, p. 1354-1363.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Fink, T, Metzner, A, Willems, S, Eckardt, L, Ince, H, Brachmann, J, Spitzer, SG, Deneke, T, Schmitt, C, Hochadel, M, Senges, J & Rillig, A 2019, 'Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry', CLIN RES CARDIOL, vol. 108, no. 12, pp. 1354-1363. https://doi.org/10.1007/s00392-019-01471-5

APA

Fink, T., Metzner, A., Willems, S., Eckardt, L., Ince, H., Brachmann, J., Spitzer, S. G., Deneke, T., Schmitt, C., Hochadel, M., Senges, J., & Rillig, A. (2019). Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry. CLIN RES CARDIOL, 108(12), 1354-1363. https://doi.org/10.1007/s00392-019-01471-5

Vancouver

Fink T, Metzner A, Willems S, Eckardt L, Ince H, Brachmann J et al. Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry. CLIN RES CARDIOL. 2019 Dec;108(12):1354-1363. https://doi.org/10.1007/s00392-019-01471-5

Bibtex

@article{5e6da7ab799c4ebda215f925ccf915dc,
title = "Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry",
abstract = "BACKGROUND: Aged patients are underrepresented in clinical trials on catheter ablation of atrial fibrillation (AF). In addition, results of outcomes after repeat ablation in the elderly are lacking. We report the results of first repeat AF ablation procedures of aged patients from a real-world multicenter prospective registry.METHODS: Patients undergoing second AF ablation included in the prospective, multicenter German Ablation Registry were divided in two groups (age > 70 years (group 1) and age ≤ 70 years (group 2)) and analyzed for procedural characteristics and clinical follow-up.RESULTS: 738 patients were analyzed (108 patients in group 1, 630 patients in group 2). Significantly more aged patients had structural heart disease (56 patients (51.9%) vs. 203 patients (32.2%), p < 0.001). The majority of the patients underwent repeat pulmonary vein isolation (101 patients (93.5%) vs. 593 patients (94.1%), p = 0.98). More aged patients underwent ablation of left atrial linear lesions (78.1% vs. 57.3% of all linear lesions, p = 0.027). There was no difference in the occurrence of peri-procedural complications (7 patients (6.5%) vs. 24 patients (3.8%), p = 0.30). Recurrence of atrial arrhythmias was documented in 45/105 (42.9%) and 252/603 (41.8%) patients with available follow-up in groups 1 and 2 after a median of 447 (400; 532) and 473 (411; 544) days (p = 0.84). A comparable amount of patients were asymptomatic or reported symptom improvement after repeat ablation in both groups (80% (80/100) in group 1 and 77% (446/576) in group 2; p = 0.57).CONCLUSION: Repeat ablation for AF in elderly patients can be performed with safety and efficacy comparable to younger patients.",
keywords = "Age Factors, Aged, Atrial Fibrillation/diagnosis, Catheter Ablation/adverse effects, Female, Germany, Humans, Male, Middle Aged, Patient Safety, Patient Satisfaction, Prospective Studies, Pulmonary Veins/physiopathology, Recurrence, Registries, Reoperation, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome",
author = "Thomas Fink and Andreas Metzner and Stephan Willems and Lars Eckardt and H{\"u}seyin Ince and Johannes Brachmann and Spitzer, {Stefan G} and Thomas Deneke and Claus Schmitt and Matthias Hochadel and Jochen Senges and Andreas Rillig",
year = "2019",
month = dec,
doi = "10.1007/s00392-019-01471-5",
language = "English",
volume = "108",
pages = "1354--1363",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "12",

}

RIS

TY - JOUR

T1 - Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry

AU - Fink, Thomas

AU - Metzner, Andreas

AU - Willems, Stephan

AU - Eckardt, Lars

AU - Ince, Hüseyin

AU - Brachmann, Johannes

AU - Spitzer, Stefan G

AU - Deneke, Thomas

AU - Schmitt, Claus

AU - Hochadel, Matthias

AU - Senges, Jochen

AU - Rillig, Andreas

PY - 2019/12

Y1 - 2019/12

N2 - BACKGROUND: Aged patients are underrepresented in clinical trials on catheter ablation of atrial fibrillation (AF). In addition, results of outcomes after repeat ablation in the elderly are lacking. We report the results of first repeat AF ablation procedures of aged patients from a real-world multicenter prospective registry.METHODS: Patients undergoing second AF ablation included in the prospective, multicenter German Ablation Registry were divided in two groups (age > 70 years (group 1) and age ≤ 70 years (group 2)) and analyzed for procedural characteristics and clinical follow-up.RESULTS: 738 patients were analyzed (108 patients in group 1, 630 patients in group 2). Significantly more aged patients had structural heart disease (56 patients (51.9%) vs. 203 patients (32.2%), p < 0.001). The majority of the patients underwent repeat pulmonary vein isolation (101 patients (93.5%) vs. 593 patients (94.1%), p = 0.98). More aged patients underwent ablation of left atrial linear lesions (78.1% vs. 57.3% of all linear lesions, p = 0.027). There was no difference in the occurrence of peri-procedural complications (7 patients (6.5%) vs. 24 patients (3.8%), p = 0.30). Recurrence of atrial arrhythmias was documented in 45/105 (42.9%) and 252/603 (41.8%) patients with available follow-up in groups 1 and 2 after a median of 447 (400; 532) and 473 (411; 544) days (p = 0.84). A comparable amount of patients were asymptomatic or reported symptom improvement after repeat ablation in both groups (80% (80/100) in group 1 and 77% (446/576) in group 2; p = 0.57).CONCLUSION: Repeat ablation for AF in elderly patients can be performed with safety and efficacy comparable to younger patients.

AB - BACKGROUND: Aged patients are underrepresented in clinical trials on catheter ablation of atrial fibrillation (AF). In addition, results of outcomes after repeat ablation in the elderly are lacking. We report the results of first repeat AF ablation procedures of aged patients from a real-world multicenter prospective registry.METHODS: Patients undergoing second AF ablation included in the prospective, multicenter German Ablation Registry were divided in two groups (age > 70 years (group 1) and age ≤ 70 years (group 2)) and analyzed for procedural characteristics and clinical follow-up.RESULTS: 738 patients were analyzed (108 patients in group 1, 630 patients in group 2). Significantly more aged patients had structural heart disease (56 patients (51.9%) vs. 203 patients (32.2%), p < 0.001). The majority of the patients underwent repeat pulmonary vein isolation (101 patients (93.5%) vs. 593 patients (94.1%), p = 0.98). More aged patients underwent ablation of left atrial linear lesions (78.1% vs. 57.3% of all linear lesions, p = 0.027). There was no difference in the occurrence of peri-procedural complications (7 patients (6.5%) vs. 24 patients (3.8%), p = 0.30). Recurrence of atrial arrhythmias was documented in 45/105 (42.9%) and 252/603 (41.8%) patients with available follow-up in groups 1 and 2 after a median of 447 (400; 532) and 473 (411; 544) days (p = 0.84). A comparable amount of patients were asymptomatic or reported symptom improvement after repeat ablation in both groups (80% (80/100) in group 1 and 77% (446/576) in group 2; p = 0.57).CONCLUSION: Repeat ablation for AF in elderly patients can be performed with safety and efficacy comparable to younger patients.

KW - Age Factors

KW - Aged

KW - Atrial Fibrillation/diagnosis

KW - Catheter Ablation/adverse effects

KW - Female

KW - Germany

KW - Humans

KW - Male

KW - Middle Aged

KW - Patient Safety

KW - Patient Satisfaction

KW - Prospective Studies

KW - Pulmonary Veins/physiopathology

KW - Recurrence

KW - Registries

KW - Reoperation

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1007/s00392-019-01471-5

DO - 10.1007/s00392-019-01471-5

M3 - SCORING: Journal article

C2 - 30953179

VL - 108

SP - 1354

EP - 1363

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 12

ER -