Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry
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Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry. / Fink, Thomas; Metzner, Andreas; Willems, Stephan; Eckardt, Lars; Ince, Hüseyin; Brachmann, Johannes; Spitzer, Stefan G; Deneke, Thomas; Schmitt, Claus; Hochadel, Matthias; Senges, Jochen; Rillig, Andreas.
in: CLIN RES CARDIOL, Jahrgang 108, Nr. 12, 12.2019, S. 1354-1363.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry
AU - Fink, Thomas
AU - Metzner, Andreas
AU - Willems, Stephan
AU - Eckardt, Lars
AU - Ince, Hüseyin
AU - Brachmann, Johannes
AU - Spitzer, Stefan G
AU - Deneke, Thomas
AU - Schmitt, Claus
AU - Hochadel, Matthias
AU - Senges, Jochen
AU - Rillig, Andreas
PY - 2019/12
Y1 - 2019/12
N2 - BACKGROUND: Aged patients are underrepresented in clinical trials on catheter ablation of atrial fibrillation (AF). In addition, results of outcomes after repeat ablation in the elderly are lacking. We report the results of first repeat AF ablation procedures of aged patients from a real-world multicenter prospective registry.METHODS: Patients undergoing second AF ablation included in the prospective, multicenter German Ablation Registry were divided in two groups (age > 70 years (group 1) and age ≤ 70 years (group 2)) and analyzed for procedural characteristics and clinical follow-up.RESULTS: 738 patients were analyzed (108 patients in group 1, 630 patients in group 2). Significantly more aged patients had structural heart disease (56 patients (51.9%) vs. 203 patients (32.2%), p < 0.001). The majority of the patients underwent repeat pulmonary vein isolation (101 patients (93.5%) vs. 593 patients (94.1%), p = 0.98). More aged patients underwent ablation of left atrial linear lesions (78.1% vs. 57.3% of all linear lesions, p = 0.027). There was no difference in the occurrence of peri-procedural complications (7 patients (6.5%) vs. 24 patients (3.8%), p = 0.30). Recurrence of atrial arrhythmias was documented in 45/105 (42.9%) and 252/603 (41.8%) patients with available follow-up in groups 1 and 2 after a median of 447 (400; 532) and 473 (411; 544) days (p = 0.84). A comparable amount of patients were asymptomatic or reported symptom improvement after repeat ablation in both groups (80% (80/100) in group 1 and 77% (446/576) in group 2; p = 0.57).CONCLUSION: Repeat ablation for AF in elderly patients can be performed with safety and efficacy comparable to younger patients.
AB - BACKGROUND: Aged patients are underrepresented in clinical trials on catheter ablation of atrial fibrillation (AF). In addition, results of outcomes after repeat ablation in the elderly are lacking. We report the results of first repeat AF ablation procedures of aged patients from a real-world multicenter prospective registry.METHODS: Patients undergoing second AF ablation included in the prospective, multicenter German Ablation Registry were divided in two groups (age > 70 years (group 1) and age ≤ 70 years (group 2)) and analyzed for procedural characteristics and clinical follow-up.RESULTS: 738 patients were analyzed (108 patients in group 1, 630 patients in group 2). Significantly more aged patients had structural heart disease (56 patients (51.9%) vs. 203 patients (32.2%), p < 0.001). The majority of the patients underwent repeat pulmonary vein isolation (101 patients (93.5%) vs. 593 patients (94.1%), p = 0.98). More aged patients underwent ablation of left atrial linear lesions (78.1% vs. 57.3% of all linear lesions, p = 0.027). There was no difference in the occurrence of peri-procedural complications (7 patients (6.5%) vs. 24 patients (3.8%), p = 0.30). Recurrence of atrial arrhythmias was documented in 45/105 (42.9%) and 252/603 (41.8%) patients with available follow-up in groups 1 and 2 after a median of 447 (400; 532) and 473 (411; 544) days (p = 0.84). A comparable amount of patients were asymptomatic or reported symptom improvement after repeat ablation in both groups (80% (80/100) in group 1 and 77% (446/576) in group 2; p = 0.57).CONCLUSION: Repeat ablation for AF in elderly patients can be performed with safety and efficacy comparable to younger patients.
KW - Age Factors
KW - Aged
KW - Atrial Fibrillation/diagnosis
KW - Catheter Ablation/adverse effects
KW - Female
KW - Germany
KW - Humans
KW - Male
KW - Middle Aged
KW - Patient Safety
KW - Patient Satisfaction
KW - Prospective Studies
KW - Pulmonary Veins/physiopathology
KW - Recurrence
KW - Registries
KW - Reoperation
KW - Risk Assessment
KW - Risk Factors
KW - Time Factors
KW - Treatment Outcome
U2 - 10.1007/s00392-019-01471-5
DO - 10.1007/s00392-019-01471-5
M3 - SCORING: Journal article
C2 - 30953179
VL - 108
SP - 1354
EP - 1363
JO - CLIN RES CARDIOL
JF - CLIN RES CARDIOL
SN - 1861-0684
IS - 12
ER -