Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients.
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Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients. / Metzner, Karin J; Rauch, Pia; Braun, Patrick; Knechten, Heribert; Ehret, Robert; Korn, Klaus; Kaiser, Rolf; Sichtig, Nadine; Ranneberg, Britta; van Lunzen, Jan; Walter, Hauke.
In: J CLIN VIROL, Vol. 50, No. 2, 2, 2011, p. 156-161.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients.
AU - Metzner, Karin J
AU - Rauch, Pia
AU - Braun, Patrick
AU - Knechten, Heribert
AU - Ehret, Robert
AU - Korn, Klaus
AU - Kaiser, Rolf
AU - Sichtig, Nadine
AU - Ranneberg, Britta
AU - van Lunzen, Jan
AU - Walter, Hauke
PY - 2011
Y1 - 2011
N2 - Minority drug-resistant HIV-1 variants, undetected by conventional genotyping, may impair the outcome of antiretroviral therapy (ART). Thus, we retrospectively analyzed the prevalence of minority drug-resistant HIV-1 variants before ART in chronically HIV-1 infected patients initiating first-line therapy and assessed the impact on clinical outcome in the prospective German Truvada cohort.
AB - Minority drug-resistant HIV-1 variants, undetected by conventional genotyping, may impair the outcome of antiretroviral therapy (ART). Thus, we retrospectively analyzed the prevalence of minority drug-resistant HIV-1 variants before ART in chronically HIV-1 infected patients initiating first-line therapy and assessed the impact on clinical outcome in the prospective German Truvada cohort.
M3 - SCORING: Zeitschriftenaufsatz
VL - 50
SP - 156
EP - 161
JO - J CLIN VIROL
JF - J CLIN VIROL
SN - 1386-6532
IS - 2
M1 - 2
ER -