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Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms.

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Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms. / Thoennissen, Nils H; Krug, Utz O; Lee, Dhong Hyun Tony; Kawamata, Norihiko; Iwanski, Gabriela; Lasho, Terra; Weiss, Tamara; Nowak, Daniel; Koren-Michowitz, Maya; Kato, Motohiro; Sanada, Masashi; Shih, Lee-Yung; Nagler, Arnon; Raynaud, Sophie D; Muller-Tidow, Carsten; Mesa, Ruben; Haferlach, Torsten; Gilliland, D Gary; Tefferi, Ayalew; Ogawa, Seishi; Koeffler, H Phillip.

In: BLOOD, Vol. 115, No. 14, 14, 2010, p. 2882-2890.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Thoennissen, NH, Krug, UO, Lee, DHT, Kawamata, N, Iwanski, G, Lasho, T, Weiss, T, Nowak, D, Koren-Michowitz, M, Kato, M, Sanada, M, Shih, L-Y, Nagler, A, Raynaud, SD, Muller-Tidow, C, Mesa, R, Haferlach, T, Gilliland, DG, Tefferi, A, Ogawa, S & Koeffler, HP 2010, 'Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms.', BLOOD, vol. 115, no. 14, 14, pp. 2882-2890. <http://www.ncbi.nlm.nih.gov/pubmed/20068225?dopt=Citation>

APA

Thoennissen, N. H., Krug, U. O., Lee, D. H. T., Kawamata, N., Iwanski, G., Lasho, T., Weiss, T., Nowak, D., Koren-Michowitz, M., Kato, M., Sanada, M., Shih, L-Y., Nagler, A., Raynaud, S. D., Muller-Tidow, C., Mesa, R., Haferlach, T., Gilliland, D. G., Tefferi, A., ... Koeffler, H. P. (2010). Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms. BLOOD, 115(14), 2882-2890. [14]. http://www.ncbi.nlm.nih.gov/pubmed/20068225?dopt=Citation

Vancouver

Thoennissen NH, Krug UO, Lee DHT, Kawamata N, Iwanski G, Lasho T et al. Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms. BLOOD. 2010;115(14):2882-2890. 14.

Bibtex

@article{2a44d77a8496472d81d06a720480f326,
title = "Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms.",
abstract = "Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia and primary myelofibrosis show an inherent tendency for transformation into leukemia (MPN-blast phase), which is hypothesized to be accompanied by acquisition of additional genomic lesions. We, therefore, examined chromosomal abnormalities by high-resolution single-nucleotide polymorphism (SNP) array in 88 MPN patients, as well as 71 cases with MPN-blast phase, and correlated these findings with their clinical parameters. Frequent genomic alterations were found in MPN after leukemic transformation with up to 3-fold more genomic changes per sample compared to samples in chronic phase (p",
author = "Thoennissen, {Nils H} and Krug, {Utz O} and Lee, {Dhong Hyun Tony} and Norihiko Kawamata and Gabriela Iwanski and Terra Lasho and Tamara Weiss and Daniel Nowak and Maya Koren-Michowitz and Motohiro Kato and Masashi Sanada and Lee-Yung Shih and Arnon Nagler and Raynaud, {Sophie D} and Carsten Muller-Tidow and Ruben Mesa and Torsten Haferlach and Gilliland, {D Gary} and Ayalew Tefferi and Seishi Ogawa and Koeffler, {H Phillip}",
year = "2010",
language = "Deutsch",
volume = "115",
pages = "2882--2890",
journal = "BLOOD",
issn = "0006-4971",
publisher = "American Society of Hematology",
number = "14",

}

RIS

TY - JOUR

T1 - Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms.

AU - Thoennissen, Nils H

AU - Krug, Utz O

AU - Lee, Dhong Hyun Tony

AU - Kawamata, Norihiko

AU - Iwanski, Gabriela

AU - Lasho, Terra

AU - Weiss, Tamara

AU - Nowak, Daniel

AU - Koren-Michowitz, Maya

AU - Kato, Motohiro

AU - Sanada, Masashi

AU - Shih, Lee-Yung

AU - Nagler, Arnon

AU - Raynaud, Sophie D

AU - Muller-Tidow, Carsten

AU - Mesa, Ruben

AU - Haferlach, Torsten

AU - Gilliland, D Gary

AU - Tefferi, Ayalew

AU - Ogawa, Seishi

AU - Koeffler, H Phillip

PY - 2010

Y1 - 2010

N2 - Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia and primary myelofibrosis show an inherent tendency for transformation into leukemia (MPN-blast phase), which is hypothesized to be accompanied by acquisition of additional genomic lesions. We, therefore, examined chromosomal abnormalities by high-resolution single-nucleotide polymorphism (SNP) array in 88 MPN patients, as well as 71 cases with MPN-blast phase, and correlated these findings with their clinical parameters. Frequent genomic alterations were found in MPN after leukemic transformation with up to 3-fold more genomic changes per sample compared to samples in chronic phase (p

AB - Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia and primary myelofibrosis show an inherent tendency for transformation into leukemia (MPN-blast phase), which is hypothesized to be accompanied by acquisition of additional genomic lesions. We, therefore, examined chromosomal abnormalities by high-resolution single-nucleotide polymorphism (SNP) array in 88 MPN patients, as well as 71 cases with MPN-blast phase, and correlated these findings with their clinical parameters. Frequent genomic alterations were found in MPN after leukemic transformation with up to 3-fold more genomic changes per sample compared to samples in chronic phase (p

M3 - SCORING: Zeitschriftenaufsatz

VL - 115

SP - 2882

EP - 2890

JO - BLOOD

JF - BLOOD

SN - 0006-4971

IS - 14

M1 - 14

ER -