PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa in primary breast cancer--outcome on prognosis.

M Untch; G von Minckwitz; G E Konecny; U Conrad; W Fett; C Kurzeder; H-J Lück; E Stickeler; H Urbaczyk; B Liedtke; M W Beckmann; C Salat; N Harbeck; Volkmar Müller; M Schmidt; S Hasmüller; M Lenhard; V Nekljudova; Annette Lebeau; S Loibl; P A Fasching; Arbeitsgemeinschaft Gynäkologische Onkologie PREPARE Investigators

PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa in primary breast cancer--outcome on prognosis.

M Untch
G von Minckwitz
G E Konecny
U Conrad
W Fett
C Kurzeder
H-J Lück
E Stickeler
H Urbaczyk
B Liedtke
M W Beckmann
C Salat
N Harbeck
Volkmar Müller
M Schmidt
S Hasmüller
M Lenhard
V Nekljudova
Annette Lebeau
S Loibl
P A Fasching
Arbeitsgemeinschaft Gynäkologische Onkologie PREPARE Investigators

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Abstract

The objective of this study was to compare the effect of dose-intensified neoadjuvant chemotherapy with that of standard epirubicin plus cyclophosphamide followed by paclitaxel in combination with or without darbepoetin on survival in primary breast cancer.

Bibliographical data

Original language	English
Article number	9
ISSN	0923-7534
Publication status	Published - 2011

pubmed	21382868

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Abstract

Bibliographical data