Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin

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Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin. / Svensson, S; Monsen, C; Kölbel, T; Acosta, S.

In: EUR J VASC ENDOVASC, Vol. 36, No. 1, 07.2008, p. 84-89.

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@article{4be806b2e1f940d085ac591baed1b110,
title = "Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin",
abstract = "OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC) therapy of peri-vascular surgical site infections in the groin after arterial surgery.DESIGN: Retrospective study.MATERIALS: Thirty-three groins received VAC therapy between August 2004 and December 2006 at Vascular Centre, Malm{\"o} University Hospital.METHODS: Following surgical revision, VAC therapy was applied in the groin at a continuous topical negative pressure of 125 mmHg. The median follow up time was 16 months.RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p<0.001).CONCLUSIONS: VAC treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC therapy were associated with amputation and death.",
keywords = "Aged, Aged, 80 and over, Amputation, Blood Vessel Prosthesis/adverse effects, Blood Vessel Prosthesis Implantation/instrumentation, Female, Femoral Artery/surgery, Groin/blood supply, Hemorrhage/etiology, Hospital Costs, Humans, Male, Middle Aged, Negative-Pressure Wound Therapy/adverse effects, Prosthesis-Related Infections/etiology, Registries, Retrospective Studies, Surgical Wound Infection/etiology, Time Factors, Treatment Outcome, Vascular Surgical Procedures/adverse effects, Wound Healing",
author = "S Svensson and C Monsen and T K{\"o}lbel and S Acosta",
year = "2008",
month = jul,
doi = "10.1016/j.ejvs.2007.12.020",
language = "English",
volume = "36",
pages = "84--89",
journal = "EUR J VASC ENDOVASC",
issn = "1078-5884",
publisher = "W.B. Saunders Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin

AU - Svensson, S

AU - Monsen, C

AU - Kölbel, T

AU - Acosta, S

PY - 2008/7

Y1 - 2008/7

N2 - OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC) therapy of peri-vascular surgical site infections in the groin after arterial surgery.DESIGN: Retrospective study.MATERIALS: Thirty-three groins received VAC therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital.METHODS: Following surgical revision, VAC therapy was applied in the groin at a continuous topical negative pressure of 125 mmHg. The median follow up time was 16 months.RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p<0.001).CONCLUSIONS: VAC treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC therapy were associated with amputation and death.

AB - OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC) therapy of peri-vascular surgical site infections in the groin after arterial surgery.DESIGN: Retrospective study.MATERIALS: Thirty-three groins received VAC therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital.METHODS: Following surgical revision, VAC therapy was applied in the groin at a continuous topical negative pressure of 125 mmHg. The median follow up time was 16 months.RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p<0.001).CONCLUSIONS: VAC treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC therapy were associated with amputation and death.

KW - Aged

KW - Aged, 80 and over

KW - Amputation

KW - Blood Vessel Prosthesis/adverse effects

KW - Blood Vessel Prosthesis Implantation/instrumentation

KW - Female

KW - Femoral Artery/surgery

KW - Groin/blood supply

KW - Hemorrhage/etiology

KW - Hospital Costs

KW - Humans

KW - Male

KW - Middle Aged

KW - Negative-Pressure Wound Therapy/adverse effects

KW - Prosthesis-Related Infections/etiology

KW - Registries

KW - Retrospective Studies

KW - Surgical Wound Infection/etiology

KW - Time Factors

KW - Treatment Outcome

KW - Vascular Surgical Procedures/adverse effects

KW - Wound Healing

U2 - 10.1016/j.ejvs.2007.12.020

DO - 10.1016/j.ejvs.2007.12.020

M3 - SCORING: Journal article

C2 - 18294875

VL - 36

SP - 84

EP - 89

JO - EUR J VASC ENDOVASC

JF - EUR J VASC ENDOVASC

SN - 1078-5884

IS - 1

ER -