Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin
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Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin. / Svensson, S; Monsen, C; Kölbel, T; Acosta, S.
in: EUR J VASC ENDOVASC, Jahrgang 36, Nr. 1, 07.2008, S. 84-89.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Predictors for outcome after vacuum assisted closure therapy of peri-vascular surgical site infections in the groin
AU - Svensson, S
AU - Monsen, C
AU - Kölbel, T
AU - Acosta, S
PY - 2008/7
Y1 - 2008/7
N2 - OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC) therapy of peri-vascular surgical site infections in the groin after arterial surgery.DESIGN: Retrospective study.MATERIALS: Thirty-three groins received VAC therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital.METHODS: Following surgical revision, VAC therapy was applied in the groin at a continuous topical negative pressure of 125 mmHg. The median follow up time was 16 months.RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p<0.001).CONCLUSIONS: VAC treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC therapy were associated with amputation and death.
AB - OBJECTIVES: To assess outcomes (wound healing, amputation and mortality) after vacuum assisted closure (VAC) therapy of peri-vascular surgical site infections in the groin after arterial surgery.DESIGN: Retrospective study.MATERIALS: Thirty-three groins received VAC therapy between August 2004 and December 2006 at Vascular Centre, Malmö University Hospital.METHODS: Following surgical revision, VAC therapy was applied in the groin at a continuous topical negative pressure of 125 mmHg. The median follow up time was 16 months.RESULTS: Median age was 75 years. Twenty-three (70%) cases underwent surgery for lower limb ischaemia. Intestinal flora was present in 88% of the wound cultures. Median duration of VAC therapy was 20 days and 27 (82%) wounds healed within 55 days. One serious VAC associated bleeding and three late false femoral artery aneurysms were reported. The median cost of VAC treatment was 2.7% of the in-hospital costs. Synthetic vascular graft infection (n=21) was associated with adverse infection-related events (n=9; p=0.012). Non-healing wounds were associated with amputation (p=0.005) and death (p<0.001).CONCLUSIONS: VAC treated synthetic vascular graft infections in the groin were at a greater risk of developing infection-related complications. Non-healing surgical site infections after VAC therapy were associated with amputation and death.
KW - Aged
KW - Aged, 80 and over
KW - Amputation
KW - Blood Vessel Prosthesis/adverse effects
KW - Blood Vessel Prosthesis Implantation/instrumentation
KW - Female
KW - Femoral Artery/surgery
KW - Groin/blood supply
KW - Hemorrhage/etiology
KW - Hospital Costs
KW - Humans
KW - Male
KW - Middle Aged
KW - Negative-Pressure Wound Therapy/adverse effects
KW - Prosthesis-Related Infections/etiology
KW - Registries
KW - Retrospective Studies
KW - Surgical Wound Infection/etiology
KW - Time Factors
KW - Treatment Outcome
KW - Vascular Surgical Procedures/adverse effects
KW - Wound Healing
U2 - 10.1016/j.ejvs.2007.12.020
DO - 10.1016/j.ejvs.2007.12.020
M3 - SCORING: Journal article
C2 - 18294875
VL - 36
SP - 84
EP - 89
JO - EUR J VASC ENDOVASC
JF - EUR J VASC ENDOVASC
SN - 1078-5884
IS - 1
ER -