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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure

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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure. / Michalick, Laura; Weidenfeld, Sarah; Grimmer, Benjamin; Fatykhova, Diana; Solymosi, Philip Daniel; Behrens, Felix; Dohmen, Melanie; Brack, Markus C; Schulz, Sabrina; Thomasch, Elisa; Simmons, Szandor; Müller-Redetzky, Holger; Suttorp, Norbert; Kurth, Florian; Neudecker, Jens; Toennies, Mario; Bauer, Torsten T; Eggeling, Stephan; Corman, Victor Max; Hocke, Andreas C; Witzenrath, Martin; Hippenstiel, Stefan; Kuebler, Wolfgang M.

In: EUR RESPIR J, Vol. 57, No. 3, 03.2021, p. 2002384.

Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

Harvard

Michalick, L, Weidenfeld, S, Grimmer, B, Fatykhova, D, Solymosi, PD, Behrens, F, Dohmen, M, Brack, MC, Schulz, S, Thomasch, E, Simmons, S, Müller-Redetzky, H, Suttorp, N, Kurth, F, Neudecker, J, Toennies, M, Bauer, TT, Eggeling, S, Corman, VM, Hocke, AC, Witzenrath, M, Hippenstiel, S & Kuebler, WM 2021, 'Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure', EUR RESPIR J, vol. 57, no. 3, pp. 2002384. https://doi.org/10.1183/13993003.02384-2020

APA

Michalick, L., Weidenfeld, S., Grimmer, B., Fatykhova, D., Solymosi, P. D., Behrens, F., Dohmen, M., Brack, M. C., Schulz, S., Thomasch, E., Simmons, S., Müller-Redetzky, H., Suttorp, N., Kurth, F., Neudecker, J., Toennies, M., Bauer, T. T., Eggeling, S., Corman, V. M., ... Kuebler, W. M. (2021). Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure. EUR RESPIR J, 57(3), 2002384. https://doi.org/10.1183/13993003.02384-2020

Vancouver

Michalick L, Weidenfeld S, Grimmer B, Fatykhova D, Solymosi PD, Behrens F et al. Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure. EUR RESPIR J. 2021 Mar;57(3):2002384. https://doi.org/10.1183/13993003.02384-2020

Bibtex

@article{dfe8e2060aaa46679684fb6bfa2065fc,
title = "Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure",
abstract = "The plasma of COVID-19 patients induces pulmonary microvascular barrier failure, which increases with disease severity. Here, a screening platform to test for plasma mediators and the therapeutic potential of barrier stabilising compounds is reported. https://bit.ly/3k4C0tB",
keywords = "Actins/metabolism, Antigens, CD/metabolism, COVID-19/blood, Cadherins/metabolism, Capillary Permeability, Case-Control Studies, Electric Impedance, Endothelial Cells/metabolism, Endothelium/metabolism, Hospitalization, Humans, Lung/metabolism, Microvessels/cytology, Occludin/metabolism, Plasma, SARS-CoV-2, Severity of Illness Index",
author = "Laura Michalick and Sarah Weidenfeld and Benjamin Grimmer and Diana Fatykhova and Solymosi, {Philip Daniel} and Felix Behrens and Melanie Dohmen and Brack, {Markus C} and Sabrina Schulz and Elisa Thomasch and Szandor Simmons and Holger M{\"u}ller-Redetzky and Norbert Suttorp and Florian Kurth and Jens Neudecker and Mario Toennies and Bauer, {Torsten T} and Stephan Eggeling and Corman, {Victor Max} and Hocke, {Andreas C} and Martin Witzenrath and Stefan Hippenstiel and Kuebler, {Wolfgang M}",
year = "2021",
month = mar,
doi = "10.1183/13993003.02384-2020",
language = "English",
volume = "57",
pages = "2002384",
journal = "EUR RESPIR J",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "3",

}

RIS

TY - JOUR

T1 - Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure

AU - Michalick, Laura

AU - Weidenfeld, Sarah

AU - Grimmer, Benjamin

AU - Fatykhova, Diana

AU - Solymosi, Philip Daniel

AU - Behrens, Felix

AU - Dohmen, Melanie

AU - Brack, Markus C

AU - Schulz, Sabrina

AU - Thomasch, Elisa

AU - Simmons, Szandor

AU - Müller-Redetzky, Holger

AU - Suttorp, Norbert

AU - Kurth, Florian

AU - Neudecker, Jens

AU - Toennies, Mario

AU - Bauer, Torsten T

AU - Eggeling, Stephan

AU - Corman, Victor Max

AU - Hocke, Andreas C

AU - Witzenrath, Martin

AU - Hippenstiel, Stefan

AU - Kuebler, Wolfgang M

PY - 2021/3

Y1 - 2021/3

N2 - The plasma of COVID-19 patients induces pulmonary microvascular barrier failure, which increases with disease severity. Here, a screening platform to test for plasma mediators and the therapeutic potential of barrier stabilising compounds is reported. https://bit.ly/3k4C0tB

AB - The plasma of COVID-19 patients induces pulmonary microvascular barrier failure, which increases with disease severity. Here, a screening platform to test for plasma mediators and the therapeutic potential of barrier stabilising compounds is reported. https://bit.ly/3k4C0tB

KW - Actins/metabolism

KW - Antigens, CD/metabolism

KW - COVID-19/blood

KW - Cadherins/metabolism

KW - Capillary Permeability

KW - Case-Control Studies

KW - Electric Impedance

KW - Endothelial Cells/metabolism

KW - Endothelium/metabolism

KW - Hospitalization

KW - Humans

KW - Lung/metabolism

KW - Microvessels/cytology

KW - Occludin/metabolism

KW - Plasma

KW - SARS-CoV-2

KW - Severity of Illness Index

U2 - 10.1183/13993003.02384-2020

DO - 10.1183/13993003.02384-2020

M3 - Other (editorial matter etc.)

C2 - 33154030

VL - 57

SP - 2002384

JO - EUR RESPIR J

JF - EUR RESPIR J

SN - 0903-1936

IS - 3

ER -