Placeboeffekte in der Akutschmerztherapie

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Placeboeffekte in der Akutschmerztherapie. / Haaga, Roland; Schnabel, Alexander.

In: ANASTH INTENSIV NOTF, Vol. 53, No. 9, 09.2018, p. 579-590.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{5baef55c91674a5e9572837456198d3e,
title = "Placeboeffekte in der Akutschmerztherapie",
abstract = "Placebo and nocebo effects are currently within the focus of clinical and experimental pain research. Neurophysiological and psychophysiological mechanisms might play an important role. Placebo and nocebo effects might be mediated through the descendent inhibitory pain pathway via endogenous opioids. Apart from that three different psychological mechanisms might be relevant for placebo and nocebo effects: classical conditioning, social learning and pain expectation. An open analgesic drug application, detailed patient information about efficacy and possible adverse events (without an extensive focus on it) of perioperative analgesic drugs and interventions and an active involvement of the patient in pain therapy (e.g. by using patient-controlled analgesia) might improve acute pain therapy via an additive placebo effect (by around 30%).",
keywords = "Acute Pain/therapy, Chronic Pain/therapy, Humans, Hyperalgesia, Nocebo Effect, Pain Management/methods, Placebo Effect",
author = "Roland Haaga and Alexander Schnabel",
note = "CME-Fortbildung",
year = "2018",
month = sep,
doi = "10.1055/s-0043-121684",
language = "Deutsch",
volume = "53",
pages = "579--590",
journal = "ANASTH INTENSIV NOTF",
issn = "0939-2661",
publisher = "Georg Thieme Verlag KG",
number = "9",

}

RIS

TY - JOUR

T1 - Placeboeffekte in der Akutschmerztherapie

AU - Haaga, Roland

AU - Schnabel, Alexander

N1 - CME-Fortbildung

PY - 2018/9

Y1 - 2018/9

N2 - Placebo and nocebo effects are currently within the focus of clinical and experimental pain research. Neurophysiological and psychophysiological mechanisms might play an important role. Placebo and nocebo effects might be mediated through the descendent inhibitory pain pathway via endogenous opioids. Apart from that three different psychological mechanisms might be relevant for placebo and nocebo effects: classical conditioning, social learning and pain expectation. An open analgesic drug application, detailed patient information about efficacy and possible adverse events (without an extensive focus on it) of perioperative analgesic drugs and interventions and an active involvement of the patient in pain therapy (e.g. by using patient-controlled analgesia) might improve acute pain therapy via an additive placebo effect (by around 30%).

AB - Placebo and nocebo effects are currently within the focus of clinical and experimental pain research. Neurophysiological and psychophysiological mechanisms might play an important role. Placebo and nocebo effects might be mediated through the descendent inhibitory pain pathway via endogenous opioids. Apart from that three different psychological mechanisms might be relevant for placebo and nocebo effects: classical conditioning, social learning and pain expectation. An open analgesic drug application, detailed patient information about efficacy and possible adverse events (without an extensive focus on it) of perioperative analgesic drugs and interventions and an active involvement of the patient in pain therapy (e.g. by using patient-controlled analgesia) might improve acute pain therapy via an additive placebo effect (by around 30%).

KW - Acute Pain/therapy

KW - Chronic Pain/therapy

KW - Humans

KW - Hyperalgesia

KW - Nocebo Effect

KW - Pain Management/methods

KW - Placebo Effect

U2 - 10.1055/s-0043-121684

DO - 10.1055/s-0043-121684

M3 - SCORING: Review

C2 - 30176686

VL - 53

SP - 579

EP - 590

JO - ANASTH INTENSIV NOTF

JF - ANASTH INTENSIV NOTF

SN - 0939-2661

IS - 9

ER -