Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse--a European pooled analysis.
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Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse--a European pooled analysis. / Janni, Wolfgang; Vogl, Florian D; Wiedswang, Gro; Synnestvedt, Marit; Fehm, Tanja; Jückstock, Julia; Borgen, Elin; Rack, Brigitte; Braun, Stephan; Sommer, Harald; Solomayer, Erich; Pantel, Klaus; Nesland, Jahn; Friese, Klaus; Naume, Bjørn.
In: CLIN CANCER RES, Vol. 17, No. 9, 9, 2011, p. 2967-2976.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse--a European pooled analysis.
AU - Janni, Wolfgang
AU - Vogl, Florian D
AU - Wiedswang, Gro
AU - Synnestvedt, Marit
AU - Fehm, Tanja
AU - Jückstock, Julia
AU - Borgen, Elin
AU - Rack, Brigitte
AU - Braun, Stephan
AU - Sommer, Harald
AU - Solomayer, Erich
AU - Pantel, Klaus
AU - Nesland, Jahn
AU - Friese, Klaus
AU - Naume, Bjørn
PY - 2011
Y1 - 2011
N2 - The prognostic significance of disseminated tumor cells (DTC) in bone marrow (BM) of breast cancer patients at the time of primary diagnosis has been confirmed by a large pooled analysis. In view of the lack of early indicators for secondary adjuvant treatment, we here evaluated whether the persistence of DTCs after adjuvant therapy increases the risk of subsequent relapse and death.
AB - The prognostic significance of disseminated tumor cells (DTC) in bone marrow (BM) of breast cancer patients at the time of primary diagnosis has been confirmed by a large pooled analysis. In view of the lack of early indicators for secondary adjuvant treatment, we here evaluated whether the persistence of DTCs after adjuvant therapy increases the risk of subsequent relapse and death.
KW - Biopsy
KW - Humans
KW - Aged
KW - Female
KW - Middle Aged
KW - Risk Factors
KW - Europe
KW - Immunohistochemistry
KW - Predictive Value of Tests
KW - Prognosis
KW - Recurrence
KW - Bone Marrow/pathology
KW - Neoplastic Cells, Circulating/pathology
KW - Bone Marrow Neoplasms/etiology/secondary
KW - Breast Neoplasms/diagnosis/mortality/pathology
KW - Carcinoma/diagnosis/mortality/pathology
KW - Biopsy
KW - Humans
KW - Aged
KW - Female
KW - Middle Aged
KW - Risk Factors
KW - Europe
KW - Immunohistochemistry
KW - Predictive Value of Tests
KW - Prognosis
KW - Recurrence
KW - Bone Marrow/pathology
KW - Neoplastic Cells, Circulating/pathology
KW - Bone Marrow Neoplasms/etiology/secondary
KW - Breast Neoplasms/diagnosis/mortality/pathology
KW - Carcinoma/diagnosis/mortality/pathology
M3 - SCORING: Journal article
VL - 17
SP - 2967
EP - 2976
JO - CLIN CANCER RES
JF - CLIN CANCER RES
SN - 1078-0432
IS - 9
M1 - 9
ER -