Research ExplorerPublicationsPeroral endoscopic myotomy for the treatment of achalasia: a...

Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study

Standard

Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. / Von Renteln, Daniel; Fuchs, Karl-Hermann; Fockens, Paul; Bauerfeind, Peter; Vassiliou, Melina C; Werner, Yuki-Birgit; Fried, Gerald; Breithaupt, Wolfram; Heinrich, Henriette; Bredenoord, Albert J; Kersten, Jan F; Verlaan, Tessa; Trevisonno, Michael; Rösch, Thomas.

In: GASTROENTEROLOGY, Vol. 145, No. 2, 01.08.2013, p. 309-11.e1-3.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Von Renteln, D, Fuchs, K-H, Fockens, P, Bauerfeind, P, Vassiliou, MC, Werner, Y-B, Fried, G, Breithaupt, W, Heinrich, H, Bredenoord, AJ, Kersten, JF, Verlaan, T, Trevisonno, M & Rösch, T 2013, 'Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study', GASTROENTEROLOGY, vol. 145, no. 2, pp. 309-11.e1-3. https://doi.org/10.1053/j.gastro.2013.04.057

APA

Von Renteln, D., Fuchs, K-H., Fockens, P., Bauerfeind, P., Vassiliou, M. C., Werner, Y-B., Fried, G., Breithaupt, W., Heinrich, H., Bredenoord, A. J., Kersten, J. F., Verlaan, T., Trevisonno, M., & Rösch, T. (2013). Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. GASTROENTEROLOGY, 145(2), 309-11.e1-3. https://doi.org/10.1053/j.gastro.2013.04.057

Vancouver

Von Renteln D, Fuchs K-H, Fockens P, Bauerfeind P, Vassiliou MC, Werner Y-B et al. Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. GASTROENTEROLOGY. 2013 Aug 1;145(2):309-11.e1-3. https://doi.org/10.1053/j.gastro.2013.04.057

Bibtex

@article{a269fac4cea94c2d898a36812b179c59,
title = "Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study",
abstract = "Pilot studies have indicated that peroral endoscopic myotomy (POEM) might be a safe and effective treatment for achalasia. We performed a prospective, international, multicenter study to determine the outcomes of 70 patients who underwent POEM at 5 centers in Europe and North America. Three months after POEM, 97% of patients were in symptom remission (95% confidence interval, 89%-99%); symptom scores were reduced from 7 to 1 (P < .001) and lower esophageal sphincter pressures were reduced from 28 to 9 mm Hg (P < .001). The percentage of patients in symptom remission at 6 and 12 months was 89% and 82%, respectively. POEM was found to be an effective treatment for achalasia after a mean follow-up period of 10 months.",
keywords = "Adult, Cohort Studies, Esophageal Achalasia, Esophagoscopy, Female, Humans, Male, Middle Aged, Natural Orifice Endoscopic Surgery, Prospective Studies, Treatment Outcome",
author = "{Von Renteln}, Daniel and Karl-Hermann Fuchs and Paul Fockens and Peter Bauerfeind and Vassiliou, {Melina C} and Yuki-Birgit Werner and Gerald Fried and Wolfram Breithaupt and Henriette Heinrich and Bredenoord, {Albert J} and Kersten, {Jan F} and Tessa Verlaan and Michael Trevisonno and Thomas R{\"o}sch",
note = "Copyright {\textcopyright} 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.",
year = "2013",
month = aug,
day = "1",
doi = "10.1053/j.gastro.2013.04.057",
language = "English",
volume = "145",
pages = "309--11.e1--3",
journal = "GASTROENTEROLOGY",
issn = "0016-5085",
publisher = "W.B. Saunders Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study

AU - Von Renteln, Daniel

AU - Fuchs, Karl-Hermann

AU - Fockens, Paul

AU - Bauerfeind, Peter

AU - Vassiliou, Melina C

AU - Werner, Yuki-Birgit

AU - Fried, Gerald

AU - Breithaupt, Wolfram

AU - Heinrich, Henriette

AU - Bredenoord, Albert J

AU - Kersten, Jan F

AU - Verlaan, Tessa

AU - Trevisonno, Michael

AU - Rösch, Thomas

N1 - Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.

PY - 2013/8/1

Y1 - 2013/8/1

N2 - Pilot studies have indicated that peroral endoscopic myotomy (POEM) might be a safe and effective treatment for achalasia. We performed a prospective, international, multicenter study to determine the outcomes of 70 patients who underwent POEM at 5 centers in Europe and North America. Three months after POEM, 97% of patients were in symptom remission (95% confidence interval, 89%-99%); symptom scores were reduced from 7 to 1 (P < .001) and lower esophageal sphincter pressures were reduced from 28 to 9 mm Hg (P < .001). The percentage of patients in symptom remission at 6 and 12 months was 89% and 82%, respectively. POEM was found to be an effective treatment for achalasia after a mean follow-up period of 10 months.

AB - Pilot studies have indicated that peroral endoscopic myotomy (POEM) might be a safe and effective treatment for achalasia. We performed a prospective, international, multicenter study to determine the outcomes of 70 patients who underwent POEM at 5 centers in Europe and North America. Three months after POEM, 97% of patients were in symptom remission (95% confidence interval, 89%-99%); symptom scores were reduced from 7 to 1 (P < .001) and lower esophageal sphincter pressures were reduced from 28 to 9 mm Hg (P < .001). The percentage of patients in symptom remission at 6 and 12 months was 89% and 82%, respectively. POEM was found to be an effective treatment for achalasia after a mean follow-up period of 10 months.

KW - Adult

KW - Cohort Studies

KW - Esophageal Achalasia

KW - Esophagoscopy

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Natural Orifice Endoscopic Surgery

KW - Prospective Studies

KW - Treatment Outcome

U2 - 10.1053/j.gastro.2013.04.057

DO - 10.1053/j.gastro.2013.04.057

M3 - SCORING: Journal article

C2 - 23665071

VL - 145

SP - 309-11.e1-3

JO - GASTROENTEROLOGY

JF - GASTROENTEROLOGY

SN - 0016-5085

IS - 2

ER -