Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients

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Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients. / Reiter, Maximilian; Kapsreiter, Markus; Betz, Christian S; Harréus, Ulrich.

In: AM J OTOLARYNG, Vol. 33, No. 6, 13.07.2012, p. 693-6.

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@article{01079ae877c64b4ba1122d581fc689a8,
title = "Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients",
abstract = "PURPOSE: Various protocols exist to prevent thrombosis after free flap surgery in the head and neck. This study reviews the outcome and incidence of perioperative complications in patients undergoing head and neck reconstruction, simply using subcutaneous low-molecular-weight heparin.MATERIALS AND METHODS: A total of 137 free tissue transfers performed between 2007 and 2010 were reviewed. All patients received a general thrombosis prophylaxis with subcutaneous low-molecular-weight enoxaparin. No aspirin, dextran, or additional antithrombotic medication was administered.RESULTS: Overall flap survival was 97.1%. A total of 3 complete and 1 partial flap loss occurred, all due to venous thrombosis. Five cases of venous congestion were successfully revised.CONCLUSION: The free flap survival rate using simple subcutaneous heparin seems to be equivalent to other management regimens. Therefore, we suggest that no additional antithrombotic treatment is needed for patients who undergo head and neck reconstruction with free tissue transfer.",
keywords = "Anticoagulants, Female, Fibrinolytic Agents, Follow-Up Studies, Free Tissue Flaps, Graft Survival, Head and Neck Neoplasms, Heparin, Low-Molecular-Weight, Humans, Injections, Subcutaneous, Male, Middle Aged, Perioperative Care, Postoperative Complications, Reconstructive Surgical Procedures, Retrospective Studies, Thrombosis, Treatment Outcome, Comparative Study, Journal Article, Multicenter Study",
author = "Maximilian Reiter and Markus Kapsreiter and Betz, {Christian S} and Ulrich Harr{\'e}us",
note = "Copyright {\textcopyright} 2012 Elsevier Inc. All rights reserved.",
year = "2012",
month = jul,
day = "13",
doi = "10.1016/j.amjoto.2012.05.008",
language = "English",
volume = "33",
pages = "693--6",
journal = "AM J OTOLARYNG",
issn = "0196-0709",
publisher = "W.B. Saunders Ltd",
number = "6",

}

RIS

TY - JOUR

T1 - Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients

AU - Reiter, Maximilian

AU - Kapsreiter, Markus

AU - Betz, Christian S

AU - Harréus, Ulrich

N1 - Copyright © 2012 Elsevier Inc. All rights reserved.

PY - 2012/7/13

Y1 - 2012/7/13

N2 - PURPOSE: Various protocols exist to prevent thrombosis after free flap surgery in the head and neck. This study reviews the outcome and incidence of perioperative complications in patients undergoing head and neck reconstruction, simply using subcutaneous low-molecular-weight heparin.MATERIALS AND METHODS: A total of 137 free tissue transfers performed between 2007 and 2010 were reviewed. All patients received a general thrombosis prophylaxis with subcutaneous low-molecular-weight enoxaparin. No aspirin, dextran, or additional antithrombotic medication was administered.RESULTS: Overall flap survival was 97.1%. A total of 3 complete and 1 partial flap loss occurred, all due to venous thrombosis. Five cases of venous congestion were successfully revised.CONCLUSION: The free flap survival rate using simple subcutaneous heparin seems to be equivalent to other management regimens. Therefore, we suggest that no additional antithrombotic treatment is needed for patients who undergo head and neck reconstruction with free tissue transfer.

AB - PURPOSE: Various protocols exist to prevent thrombosis after free flap surgery in the head and neck. This study reviews the outcome and incidence of perioperative complications in patients undergoing head and neck reconstruction, simply using subcutaneous low-molecular-weight heparin.MATERIALS AND METHODS: A total of 137 free tissue transfers performed between 2007 and 2010 were reviewed. All patients received a general thrombosis prophylaxis with subcutaneous low-molecular-weight enoxaparin. No aspirin, dextran, or additional antithrombotic medication was administered.RESULTS: Overall flap survival was 97.1%. A total of 3 complete and 1 partial flap loss occurred, all due to venous thrombosis. Five cases of venous congestion were successfully revised.CONCLUSION: The free flap survival rate using simple subcutaneous heparin seems to be equivalent to other management regimens. Therefore, we suggest that no additional antithrombotic treatment is needed for patients who undergo head and neck reconstruction with free tissue transfer.

KW - Anticoagulants

KW - Female

KW - Fibrinolytic Agents

KW - Follow-Up Studies

KW - Free Tissue Flaps

KW - Graft Survival

KW - Head and Neck Neoplasms

KW - Heparin, Low-Molecular-Weight

KW - Humans

KW - Injections, Subcutaneous

KW - Male

KW - Middle Aged

KW - Perioperative Care

KW - Postoperative Complications

KW - Reconstructive Surgical Procedures

KW - Retrospective Studies

KW - Thrombosis

KW - Treatment Outcome

KW - Comparative Study

KW - Journal Article

KW - Multicenter Study

U2 - 10.1016/j.amjoto.2012.05.008

DO - 10.1016/j.amjoto.2012.05.008

M3 - SCORING: Journal article

C2 - 22784585

VL - 33

SP - 693

EP - 696

JO - AM J OTOLARYNG

JF - AM J OTOLARYNG

SN - 0196-0709

IS - 6

ER -