Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients
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Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients. / Reiter, Maximilian; Kapsreiter, Markus; Betz, Christian S; Harréus, Ulrich.
in: AM J OTOLARYNG, Jahrgang 33, Nr. 6, 13.07.2012, S. 693-6.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Perioperative management of antithrombotic medication in head and neck reconstruction-a retrospective analysis of 137 patients
AU - Reiter, Maximilian
AU - Kapsreiter, Markus
AU - Betz, Christian S
AU - Harréus, Ulrich
N1 - Copyright © 2012 Elsevier Inc. All rights reserved.
PY - 2012/7/13
Y1 - 2012/7/13
N2 - PURPOSE: Various protocols exist to prevent thrombosis after free flap surgery in the head and neck. This study reviews the outcome and incidence of perioperative complications in patients undergoing head and neck reconstruction, simply using subcutaneous low-molecular-weight heparin.MATERIALS AND METHODS: A total of 137 free tissue transfers performed between 2007 and 2010 were reviewed. All patients received a general thrombosis prophylaxis with subcutaneous low-molecular-weight enoxaparin. No aspirin, dextran, or additional antithrombotic medication was administered.RESULTS: Overall flap survival was 97.1%. A total of 3 complete and 1 partial flap loss occurred, all due to venous thrombosis. Five cases of venous congestion were successfully revised.CONCLUSION: The free flap survival rate using simple subcutaneous heparin seems to be equivalent to other management regimens. Therefore, we suggest that no additional antithrombotic treatment is needed for patients who undergo head and neck reconstruction with free tissue transfer.
AB - PURPOSE: Various protocols exist to prevent thrombosis after free flap surgery in the head and neck. This study reviews the outcome and incidence of perioperative complications in patients undergoing head and neck reconstruction, simply using subcutaneous low-molecular-weight heparin.MATERIALS AND METHODS: A total of 137 free tissue transfers performed between 2007 and 2010 were reviewed. All patients received a general thrombosis prophylaxis with subcutaneous low-molecular-weight enoxaparin. No aspirin, dextran, or additional antithrombotic medication was administered.RESULTS: Overall flap survival was 97.1%. A total of 3 complete and 1 partial flap loss occurred, all due to venous thrombosis. Five cases of venous congestion were successfully revised.CONCLUSION: The free flap survival rate using simple subcutaneous heparin seems to be equivalent to other management regimens. Therefore, we suggest that no additional antithrombotic treatment is needed for patients who undergo head and neck reconstruction with free tissue transfer.
KW - Anticoagulants
KW - Female
KW - Fibrinolytic Agents
KW - Follow-Up Studies
KW - Free Tissue Flaps
KW - Graft Survival
KW - Head and Neck Neoplasms
KW - Heparin, Low-Molecular-Weight
KW - Humans
KW - Injections, Subcutaneous
KW - Male
KW - Middle Aged
KW - Perioperative Care
KW - Postoperative Complications
KW - Reconstructive Surgical Procedures
KW - Retrospective Studies
KW - Thrombosis
KW - Treatment Outcome
KW - Comparative Study
KW - Journal Article
KW - Multicenter Study
U2 - 10.1016/j.amjoto.2012.05.008
DO - 10.1016/j.amjoto.2012.05.008
M3 - SCORING: Journal article
C2 - 22784585
VL - 33
SP - 693
EP - 696
JO - AM J OTOLARYNG
JF - AM J OTOLARYNG
SN - 0196-0709
IS - 6
ER -