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Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease

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Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease. / Hahn, A; Claviez, A; Brinkmann, G; Altermatt, H J; Schneppenheim, R; Stephani, U.

In: NEUROPEDIATRICS, Vol. 31, No. 1, 01.02.2000, p. 42-4.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Hahn, A, Claviez, A, Brinkmann, G, Altermatt, HJ, Schneppenheim, R & Stephani, U 2000, 'Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease', NEUROPEDIATRICS, vol. 31, no. 1, pp. 42-4. https://doi.org/10.1055/s-2000-15297

APA

Hahn, A., Claviez, A., Brinkmann, G., Altermatt, H. J., Schneppenheim, R., & Stephani, U. (2000). Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease. NEUROPEDIATRICS, 31(1), 42-4. https://doi.org/10.1055/s-2000-15297

Vancouver

Hahn A, Claviez A, Brinkmann G, Altermatt HJ, Schneppenheim R, Stephani U. Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease. NEUROPEDIATRICS. 2000 Feb 1;31(1):42-4. https://doi.org/10.1055/s-2000-15297

Bibtex

@article{6958d65b6f3a48c3bb2c8ee9cbd9eaec,
title = "Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease",
abstract = "Paraneoplastic cerebellar degeneration (PCD) is a rare neurological complication in adults with extracerebral neoplasms. It is characterized by a diffuse cerebellar dysfunction, usually leading to severe neurological sequelae. In childhood, this complication is extremely rare. We report on PCD as primary manifestation of Hodgkin disease (HD) in a thirteen-year old boy. On magnetic resonance imaging, irreversible atrophy of the cerebellum developed within three months. Antibodies against Purkinje cells were detectable at diagnosis and normalised after successful treatment of the lymphoma. Cerebellar symptoms, however, only partially resolved. The necessity of a search for a malignant tumour is emphasised in the presence of an otherwise unexplained, subacutely developing, diffuse cerebellar dysfunction.",
keywords = "Adolescent, Adult, Cerebellum, Diagnosis, Differential, Follow-Up Studies, Hodgkin Disease, Humans, Magnetic Resonance Imaging, Male, Paraneoplastic Cerebellar Degeneration",
author = "A Hahn and A Claviez and G Brinkmann and Altermatt, {H J} and R Schneppenheim and U Stephani",
year = "2000",
month = feb,
day = "1",
doi = "10.1055/s-2000-15297",
language = "English",
volume = "31",
pages = "42--4",
journal = "NEUROPEDIATRICS",
issn = "0174-304X",
publisher = "Hippokrates Verlag GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease

AU - Hahn, A

AU - Claviez, A

AU - Brinkmann, G

AU - Altermatt, H J

AU - Schneppenheim, R

AU - Stephani, U

PY - 2000/2/1

Y1 - 2000/2/1

N2 - Paraneoplastic cerebellar degeneration (PCD) is a rare neurological complication in adults with extracerebral neoplasms. It is characterized by a diffuse cerebellar dysfunction, usually leading to severe neurological sequelae. In childhood, this complication is extremely rare. We report on PCD as primary manifestation of Hodgkin disease (HD) in a thirteen-year old boy. On magnetic resonance imaging, irreversible atrophy of the cerebellum developed within three months. Antibodies against Purkinje cells were detectable at diagnosis and normalised after successful treatment of the lymphoma. Cerebellar symptoms, however, only partially resolved. The necessity of a search for a malignant tumour is emphasised in the presence of an otherwise unexplained, subacutely developing, diffuse cerebellar dysfunction.

AB - Paraneoplastic cerebellar degeneration (PCD) is a rare neurological complication in adults with extracerebral neoplasms. It is characterized by a diffuse cerebellar dysfunction, usually leading to severe neurological sequelae. In childhood, this complication is extremely rare. We report on PCD as primary manifestation of Hodgkin disease (HD) in a thirteen-year old boy. On magnetic resonance imaging, irreversible atrophy of the cerebellum developed within three months. Antibodies against Purkinje cells were detectable at diagnosis and normalised after successful treatment of the lymphoma. Cerebellar symptoms, however, only partially resolved. The necessity of a search for a malignant tumour is emphasised in the presence of an otherwise unexplained, subacutely developing, diffuse cerebellar dysfunction.

KW - Adolescent

KW - Adult

KW - Cerebellum

KW - Diagnosis, Differential

KW - Follow-Up Studies

KW - Hodgkin Disease

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Paraneoplastic Cerebellar Degeneration

U2 - 10.1055/s-2000-15297

DO - 10.1055/s-2000-15297

M3 - SCORING: Journal article

C2 - 10774996

VL - 31

SP - 42

EP - 44

JO - NEUROPEDIATRICS

JF - NEUROPEDIATRICS

SN - 0174-304X

IS - 1

ER -