Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia.

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Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia. / Schmidt, C A; Oettle, H; Ludwig, W D; Serke, S; Pawlaczyk-Peter, B; Wilborn, F; Binder, Thomas; Huhn, D; Siegert, W.

In: LEUKEMIA RES, Vol. 18, No. 6, 6, 1994, p. 409-413.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Schmidt, CA, Oettle, H, Ludwig, WD, Serke, S, Pawlaczyk-Peter, B, Wilborn, F, Binder, T, Huhn, D & Siegert, W 1994, 'Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia.', LEUKEMIA RES, vol. 18, no. 6, 6, pp. 409-413. <http://www.ncbi.nlm.nih.gov/pubmed/8207958?dopt=Citation>

APA

Schmidt, C. A., Oettle, H., Ludwig, W. D., Serke, S., Pawlaczyk-Peter, B., Wilborn, F., Binder, T., Huhn, D., & Siegert, W. (1994). Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia. LEUKEMIA RES, 18(6), 409-413. [6]. http://www.ncbi.nlm.nih.gov/pubmed/8207958?dopt=Citation

Vancouver

Schmidt CA, Oettle H, Ludwig WD, Serke S, Pawlaczyk-Peter B, Wilborn F et al. Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia. LEUKEMIA RES. 1994;18(6):409-413. 6.

Bibtex

@article{23812f3a855040139ebfc6abde8207d3,
title = "Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia.",
abstract = "The Raf-1 protein, a cytoplasmic serine/threonine kinase, plays an important role in signal transduction pathways. In order to examine the role of Raf-1 in human myeloid leukemia, we determined raf-1 mRNA expression by Northern blot analysis in blast cell samples from 27 acute myeloid leukemia (AML) cases and peripheral blood mononuclear cells from six healthy donors. A normal raf-1 transcript size was detected in all cases investigated. However, overexpression of raf-1 mRNA was found in 2 of 27 AML cases, both of which were erythroleukemias (AML, FAB M6).",
author = "Schmidt, {C A} and H Oettle and Ludwig, {W D} and S Serke and B Pawlaczyk-Peter and F Wilborn and Thomas Binder and D Huhn and W Siegert",
year = "1994",
language = "Deutsch",
volume = "18",
pages = "409--413",
journal = "LEUKEMIA RES",
issn = "0145-2126",
publisher = "Elsevier Limited",
number = "6",

}

RIS

TY - JOUR

T1 - Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia.

AU - Schmidt, C A

AU - Oettle, H

AU - Ludwig, W D

AU - Serke, S

AU - Pawlaczyk-Peter, B

AU - Wilborn, F

AU - Binder, Thomas

AU - Huhn, D

AU - Siegert, W

PY - 1994

Y1 - 1994

N2 - The Raf-1 protein, a cytoplasmic serine/threonine kinase, plays an important role in signal transduction pathways. In order to examine the role of Raf-1 in human myeloid leukemia, we determined raf-1 mRNA expression by Northern blot analysis in blast cell samples from 27 acute myeloid leukemia (AML) cases and peripheral blood mononuclear cells from six healthy donors. A normal raf-1 transcript size was detected in all cases investigated. However, overexpression of raf-1 mRNA was found in 2 of 27 AML cases, both of which were erythroleukemias (AML, FAB M6).

AB - The Raf-1 protein, a cytoplasmic serine/threonine kinase, plays an important role in signal transduction pathways. In order to examine the role of Raf-1 in human myeloid leukemia, we determined raf-1 mRNA expression by Northern blot analysis in blast cell samples from 27 acute myeloid leukemia (AML) cases and peripheral blood mononuclear cells from six healthy donors. A normal raf-1 transcript size was detected in all cases investigated. However, overexpression of raf-1 mRNA was found in 2 of 27 AML cases, both of which were erythroleukemias (AML, FAB M6).

M3 - SCORING: Zeitschriftenaufsatz

VL - 18

SP - 409

EP - 413

JO - LEUKEMIA RES

JF - LEUKEMIA RES

SN - 0145-2126

IS - 6

M1 - 6

ER -