Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.

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Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression. / Kornfeld, Jan; Meder, Stephanie; Wohlberg, M; Friedrich, Reinhard; Rau, Thomas; Riethdorf, L; Löning, Thomas; Pantel, Klaus; Riethdorf, Sabine.

In: BRIT J CANCER, Vol. 104, No. 1, 1, 04.01.2011, p. 138-145.

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@article{21420ea4abb94e279283279dedef9b8b,
title = "Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.",
abstract = "TACE/ADAM17 is a transmembranous protease that cleaves membrane-bound growth factors like EGFR ligands. TACE-dependent proteolysis is regulated by its inhibitor, tissue inhibitor of metalloproteinases 3 (TIMP3). This study analyses the role of TACE and TIMP3 mRNA expression in squamous cell carcinomas of the head and neck (HNSCCs).",
keywords = "ADAM Proteins, Carcinoma, Carcinoma, Squamous Cell, Disease Progression, Female, Follow-Up Studies, Head and Neck Neoplasms, Humans, Immunoenzyme Techniques, In Situ Hybridization, Lymphatic Metastasis, Male, Middle Aged, Neoplasm Staging, Neoplasms, Squamous Cell, Prognosis, RNA Probes, RNA, Messenger, Survival Rate, Tissue Inhibitor of Metalloproteinase-3, Tumor Cells, Cultured, Tumor Markers, Biological",
author = "Jan Kornfeld and Stephanie Meder and M Wohlberg and Reinhard Friedrich and Thomas Rau and L Riethdorf and Thomas L{\"o}ning and Klaus Pantel and Sabine Riethdorf",
year = "2011",
month = jan,
day = "4",
doi = "10.1038/sj.bjc.6606017",
language = "English",
volume = "104",
pages = "138--145",
journal = "BRIT J CANCER",
issn = "0007-0920",
publisher = "NATURE PUBLISHING GROUP",
number = "1",

}

RIS

TY - JOUR

T1 - Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.

AU - Kornfeld, Jan

AU - Meder, Stephanie

AU - Wohlberg, M

AU - Friedrich, Reinhard

AU - Rau, Thomas

AU - Riethdorf, L

AU - Löning, Thomas

AU - Pantel, Klaus

AU - Riethdorf, Sabine

PY - 2011/1/4

Y1 - 2011/1/4

N2 - TACE/ADAM17 is a transmembranous protease that cleaves membrane-bound growth factors like EGFR ligands. TACE-dependent proteolysis is regulated by its inhibitor, tissue inhibitor of metalloproteinases 3 (TIMP3). This study analyses the role of TACE and TIMP3 mRNA expression in squamous cell carcinomas of the head and neck (HNSCCs).

AB - TACE/ADAM17 is a transmembranous protease that cleaves membrane-bound growth factors like EGFR ligands. TACE-dependent proteolysis is regulated by its inhibitor, tissue inhibitor of metalloproteinases 3 (TIMP3). This study analyses the role of TACE and TIMP3 mRNA expression in squamous cell carcinomas of the head and neck (HNSCCs).

KW - ADAM Proteins

KW - Carcinoma

KW - Carcinoma, Squamous Cell

KW - Disease Progression

KW - Female

KW - Follow-Up Studies

KW - Head and Neck Neoplasms

KW - Humans

KW - Immunoenzyme Techniques

KW - In Situ Hybridization

KW - Lymphatic Metastasis

KW - Male

KW - Middle Aged

KW - Neoplasm Staging

KW - Neoplasms, Squamous Cell

KW - Prognosis

KW - RNA Probes

KW - RNA, Messenger

KW - Survival Rate

KW - Tissue Inhibitor of Metalloproteinase-3

KW - Tumor Cells, Cultured

KW - Tumor Markers, Biological

U2 - 10.1038/sj.bjc.6606017

DO - 10.1038/sj.bjc.6606017

M3 - SCORING: Journal article

C2 - 21102583

VL - 104

SP - 138

EP - 145

JO - BRIT J CANCER

JF - BRIT J CANCER

SN - 0007-0920

IS - 1

M1 - 1

ER -