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Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis

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Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis. / Thombs, Brett D; Levis, Brooke; Lyubenova, Anita; Neupane, Dipika; Negeri, Zelalem; Wu, Yin; Sun, Ying; He, Chen; Krishnan, Ankur; Vigod, Simone N; Bhandari, Parash Mani; Imran, Mahrukh; Rice, Danielle B; Azar, Marleine; Chiovitti, Matthew J; Saadat, Nazanin; Riehm, Kira E; Boruff, Jill T; Cuijpers, Pim; Gilbody, Simon; Ioannidis, John P A; Kloda, Lorie A; Patten, Scott B; Shrier, Ian; Ziegelstein, Roy C; Comeau, Liane; Mitchell, Nicholas D; Tonelli, Marcello; Barnes, Jacqueline; Beck, Cheryl Tatano; Bindt, Carola; Figueiredo, Barbara; Helle, Nadine; Howard, Louise M; Kohlhoff, Jane; Kozinszky, Zoltán; Leonardou, Angeliki A; Radoš, Sandra Nakić; Quispel, Chantal; Rochat, Tamsen J; Stein, Alan; Stewart, Robert C; Tadinac, Meri; Tandon, S Darius; Tendais, Iva; Töreki, Annamária; Tran, Thach D; Trevillion, Kylee; Turner, Katherine; Vega-Dienstmaier, Johann M; Benedetti, Andrea.

In: CAN J PSYCHIAT, Vol. 65, No. 12, 12.2020, p. 835-844.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Thombs, BD, Levis, B, Lyubenova, A, Neupane, D, Negeri, Z, Wu, Y, Sun, Y, He, C, Krishnan, A, Vigod, SN, Bhandari, PM, Imran, M, Rice, DB, Azar, M, Chiovitti, MJ, Saadat, N, Riehm, KE, Boruff, JT, Cuijpers, P, Gilbody, S, Ioannidis, JPA, Kloda, LA, Patten, SB, Shrier, I, Ziegelstein, RC, Comeau, L, Mitchell, ND, Tonelli, M, Barnes, J, Beck, CT, Bindt, C, Figueiredo, B, Helle, N, Howard, LM, Kohlhoff, J, Kozinszky, Z, Leonardou, AA, Radoš, SN, Quispel, C, Rochat, TJ, Stein, A, Stewart, RC, Tadinac, M, Tandon, SD, Tendais, I, Töreki, A, Tran, TD, Trevillion, K, Turner, K, Vega-Dienstmaier, JM & Benedetti, A 2020, 'Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis', CAN J PSYCHIAT, vol. 65, no. 12, pp. 835-844. https://doi.org/10.1177/0706743720934959

APA

Thombs, B. D., Levis, B., Lyubenova, A., Neupane, D., Negeri, Z., Wu, Y., Sun, Y., He, C., Krishnan, A., Vigod, S. N., Bhandari, P. M., Imran, M., Rice, D. B., Azar, M., Chiovitti, M. J., Saadat, N., Riehm, K. E., Boruff, J. T., Cuijpers, P., ... Benedetti, A. (2020). Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis. CAN J PSYCHIAT, 65(12), 835-844. https://doi.org/10.1177/0706743720934959

Vancouver

Thombs BD, Levis B, Lyubenova A, Neupane D, Negeri Z, Wu Y et al. Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis. CAN J PSYCHIAT. 2020 Dec;65(12):835-844. https://doi.org/10.1177/0706743720934959

Bibtex

@article{6b0e687f7e7043e590d9350faa46ca3f,
title = "Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis",
abstract = "OBJECTIVE: The Maternal Mental Health in Canada, 2018/2019, survey reported that 18% of 7,085 mothers who recently gave birth reported {"}feelings consistent with postpartum depression{"} based on scores ≥7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS-5). The EPDS-5 was designed as a screening questionnaire, not to classify disorders or estimate prevalence; the extent to which EPDS-5 results reflect depression prevalence is unknown. We investigated EPDS-5 ≥7 performance relative to major depression prevalence based on a validated diagnostic interview, the Structured Clinical Interview for DSM (SCID).METHODS: We searched Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO, and the Web of Science Core Collection through June 2016 for studies with data sets with item response data to calculate EPDS-5 scores and that used the SCID to ascertain depression status. We conducted an individual participant data meta-analysis to estimate pooled percentage of EPDS-5 ≥7, pooled SCID major depression prevalence, and the pooled difference in prevalence.RESULTS: A total of 3,958 participants from 19 primary studies were included. Pooled prevalence of SCID major depression was 9.2% (95% confidence interval [CI] 6.0% to 13.7%), pooled percentage of participants with EPDS-5 ≥7 was 16.2% (95% CI 10.7% to 23.8%), and pooled difference was 8.0% (95% CI 2.9% to 13.2%). In the 19 included studies, mean and median ratios of EPDS-5 to SCID prevalence were 2.1 and 1.4 times.CONCLUSIONS: Prevalence estimated based on EPDS-5 ≥7 appears to be substantially higher than the prevalence of major depression. Validated diagnostic interviews should be used to establish prevalence.",
author = "Thombs, {Brett D} and Brooke Levis and Anita Lyubenova and Dipika Neupane and Zelalem Negeri and Yin Wu and Ying Sun and Chen He and Ankur Krishnan and Vigod, {Simone N} and Bhandari, {Parash Mani} and Mahrukh Imran and Rice, {Danielle B} and Marleine Azar and Chiovitti, {Matthew J} and Nazanin Saadat and Riehm, {Kira E} and Boruff, {Jill T} and Pim Cuijpers and Simon Gilbody and Ioannidis, {John P A} and Kloda, {Lorie A} and Patten, {Scott B} and Ian Shrier and Ziegelstein, {Roy C} and Liane Comeau and Mitchell, {Nicholas D} and Marcello Tonelli and Jacqueline Barnes and Beck, {Cheryl Tatano} and Carola Bindt and Barbara Figueiredo and Nadine Helle and Howard, {Louise M} and Jane Kohlhoff and Zolt{\'a}n Kozinszky and Leonardou, {Angeliki A} and Rado{\v s}, {Sandra Naki{\'c}} and Chantal Quispel and Rochat, {Tamsen J} and Alan Stein and Stewart, {Robert C} and Meri Tadinac and Tandon, {S Darius} and Iva Tendais and Annam{\'a}ria T{\"o}reki and Tran, {Thach D} and Kylee Trevillion and Katherine Turner and Vega-Dienstmaier, {Johann M} and Andrea Benedetti",
year = "2020",
month = dec,
doi = "10.1177/0706743720934959",
language = "English",
volume = "65",
pages = "835--844",
journal = "CAN J PSYCHIAT",
issn = "0706-7437",
publisher = "Canadian Psychiatric Association",
number = "12",

}

RIS

TY - JOUR

T1 - Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis

AU - Thombs, Brett D

AU - Levis, Brooke

AU - Lyubenova, Anita

AU - Neupane, Dipika

AU - Negeri, Zelalem

AU - Wu, Yin

AU - Sun, Ying

AU - He, Chen

AU - Krishnan, Ankur

AU - Vigod, Simone N

AU - Bhandari, Parash Mani

AU - Imran, Mahrukh

AU - Rice, Danielle B

AU - Azar, Marleine

AU - Chiovitti, Matthew J

AU - Saadat, Nazanin

AU - Riehm, Kira E

AU - Boruff, Jill T

AU - Cuijpers, Pim

AU - Gilbody, Simon

AU - Ioannidis, John P A

AU - Kloda, Lorie A

AU - Patten, Scott B

AU - Shrier, Ian

AU - Ziegelstein, Roy C

AU - Comeau, Liane

AU - Mitchell, Nicholas D

AU - Tonelli, Marcello

AU - Barnes, Jacqueline

AU - Beck, Cheryl Tatano

AU - Bindt, Carola

AU - Figueiredo, Barbara

AU - Helle, Nadine

AU - Howard, Louise M

AU - Kohlhoff, Jane

AU - Kozinszky, Zoltán

AU - Leonardou, Angeliki A

AU - Radoš, Sandra Nakić

AU - Quispel, Chantal

AU - Rochat, Tamsen J

AU - Stein, Alan

AU - Stewart, Robert C

AU - Tadinac, Meri

AU - Tandon, S Darius

AU - Tendais, Iva

AU - Töreki, Annamária

AU - Tran, Thach D

AU - Trevillion, Kylee

AU - Turner, Katherine

AU - Vega-Dienstmaier, Johann M

AU - Benedetti, Andrea

PY - 2020/12

Y1 - 2020/12

N2 - OBJECTIVE: The Maternal Mental Health in Canada, 2018/2019, survey reported that 18% of 7,085 mothers who recently gave birth reported "feelings consistent with postpartum depression" based on scores ≥7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS-5). The EPDS-5 was designed as a screening questionnaire, not to classify disorders or estimate prevalence; the extent to which EPDS-5 results reflect depression prevalence is unknown. We investigated EPDS-5 ≥7 performance relative to major depression prevalence based on a validated diagnostic interview, the Structured Clinical Interview for DSM (SCID).METHODS: We searched Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO, and the Web of Science Core Collection through June 2016 for studies with data sets with item response data to calculate EPDS-5 scores and that used the SCID to ascertain depression status. We conducted an individual participant data meta-analysis to estimate pooled percentage of EPDS-5 ≥7, pooled SCID major depression prevalence, and the pooled difference in prevalence.RESULTS: A total of 3,958 participants from 19 primary studies were included. Pooled prevalence of SCID major depression was 9.2% (95% confidence interval [CI] 6.0% to 13.7%), pooled percentage of participants with EPDS-5 ≥7 was 16.2% (95% CI 10.7% to 23.8%), and pooled difference was 8.0% (95% CI 2.9% to 13.2%). In the 19 included studies, mean and median ratios of EPDS-5 to SCID prevalence were 2.1 and 1.4 times.CONCLUSIONS: Prevalence estimated based on EPDS-5 ≥7 appears to be substantially higher than the prevalence of major depression. Validated diagnostic interviews should be used to establish prevalence.

AB - OBJECTIVE: The Maternal Mental Health in Canada, 2018/2019, survey reported that 18% of 7,085 mothers who recently gave birth reported "feelings consistent with postpartum depression" based on scores ≥7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS-5). The EPDS-5 was designed as a screening questionnaire, not to classify disorders or estimate prevalence; the extent to which EPDS-5 results reflect depression prevalence is unknown. We investigated EPDS-5 ≥7 performance relative to major depression prevalence based on a validated diagnostic interview, the Structured Clinical Interview for DSM (SCID).METHODS: We searched Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO, and the Web of Science Core Collection through June 2016 for studies with data sets with item response data to calculate EPDS-5 scores and that used the SCID to ascertain depression status. We conducted an individual participant data meta-analysis to estimate pooled percentage of EPDS-5 ≥7, pooled SCID major depression prevalence, and the pooled difference in prevalence.RESULTS: A total of 3,958 participants from 19 primary studies were included. Pooled prevalence of SCID major depression was 9.2% (95% confidence interval [CI] 6.0% to 13.7%), pooled percentage of participants with EPDS-5 ≥7 was 16.2% (95% CI 10.7% to 23.8%), and pooled difference was 8.0% (95% CI 2.9% to 13.2%). In the 19 included studies, mean and median ratios of EPDS-5 to SCID prevalence were 2.1 and 1.4 times.CONCLUSIONS: Prevalence estimated based on EPDS-5 ≥7 appears to be substantially higher than the prevalence of major depression. Validated diagnostic interviews should be used to establish prevalence.

U2 - 10.1177/0706743720934959

DO - 10.1177/0706743720934959

M3 - SCORING: Journal article

C2 - 33104415

VL - 65

SP - 835

EP - 844

JO - CAN J PSYCHIAT

JF - CAN J PSYCHIAT

SN - 0706-7437

IS - 12

ER -