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One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites.

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One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites. / Iwersen-Bergmann, Stefanie; Schmoldt, A.

In: J ANAL TOXICOL, Vol. 20, No. 5, 5, 1996, p. 301-304.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Iwersen-Bergmann, S & Schmoldt, A 1996, 'One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites.', J ANAL TOXICOL, vol. 20, no. 5, 5, pp. 301-304. <http://www.ncbi.nlm.nih.gov/pubmed/8872238?dopt=Citation>

APA

Iwersen-Bergmann, S., & Schmoldt, A. (1996). One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites. J ANAL TOXICOL, 20(5), 301-304. [5]. http://www.ncbi.nlm.nih.gov/pubmed/8872238?dopt=Citation

Vancouver

Iwersen-Bergmann S, Schmoldt A. One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites. J ANAL TOXICOL. 1996;20(5):301-304. 5.

Bibtex

@article{2a3ac8c1c3434b4098355f17d2136a20,
title = "One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites.",
abstract = "Two very different cases of overdose with tranylcypromine are presented. One clinical case involving the ingestion of 400 mg tranylcypromine with suicidal intention and one fatality with a suspicion of possible tranylcypromine overdose were examined. Both cases showed similar blood concentrations (0.5 and 0.7 mg/L, respectively), but the clinical case exhibited only mild symptoms of intoxication. The fatality showed no other drugs that could provide an explanation for the death of a 40-year-old male except tranylcypromine. Consideration of the drug concentrations in the fatality in relation to the case findings and other reported data indicates the tranylcypromine overdose as the probable cause of death, despite the low blood concentration. In addition, we looked for evidence of amphetamine as a putative metabolite in both cases. No amphetamines were detected in the overdose cases reported here.",
keywords = "Adult, Humans, Male, Fatal Outcome, Suicide, Amphetamines/*analysis/chemistry/metabolism, Gas Chromatography-Mass Spectrometry/methods, Monoamine Oxidase Inhibitors/chemistry/*metabolism/poisoning, Tranylcypromine/chemistry/*metabolism/poisoning, Adult, Humans, Male, Fatal Outcome, Suicide, Amphetamines/*analysis/chemistry/metabolism, Gas Chromatography-Mass Spectrometry/methods, Monoamine Oxidase Inhibitors/chemistry/*metabolism/poisoning, Tranylcypromine/chemistry/*metabolism/poisoning",
author = "Stefanie Iwersen-Bergmann and A Schmoldt",
year = "1996",
language = "English",
volume = "20",
pages = "301--304",
journal = "J ANAL TOXICOL",
issn = "0146-4760",
publisher = "Preston Publications",
number = "5",

}

RIS

TY - JOUR

T1 - One fatal and one nonfatal intoxication with tranylcypromine. Absence of amphetamines as metabolites.

AU - Iwersen-Bergmann, Stefanie

AU - Schmoldt, A

PY - 1996

Y1 - 1996

N2 - Two very different cases of overdose with tranylcypromine are presented. One clinical case involving the ingestion of 400 mg tranylcypromine with suicidal intention and one fatality with a suspicion of possible tranylcypromine overdose were examined. Both cases showed similar blood concentrations (0.5 and 0.7 mg/L, respectively), but the clinical case exhibited only mild symptoms of intoxication. The fatality showed no other drugs that could provide an explanation for the death of a 40-year-old male except tranylcypromine. Consideration of the drug concentrations in the fatality in relation to the case findings and other reported data indicates the tranylcypromine overdose as the probable cause of death, despite the low blood concentration. In addition, we looked for evidence of amphetamine as a putative metabolite in both cases. No amphetamines were detected in the overdose cases reported here.

AB - Two very different cases of overdose with tranylcypromine are presented. One clinical case involving the ingestion of 400 mg tranylcypromine with suicidal intention and one fatality with a suspicion of possible tranylcypromine overdose were examined. Both cases showed similar blood concentrations (0.5 and 0.7 mg/L, respectively), but the clinical case exhibited only mild symptoms of intoxication. The fatality showed no other drugs that could provide an explanation for the death of a 40-year-old male except tranylcypromine. Consideration of the drug concentrations in the fatality in relation to the case findings and other reported data indicates the tranylcypromine overdose as the probable cause of death, despite the low blood concentration. In addition, we looked for evidence of amphetamine as a putative metabolite in both cases. No amphetamines were detected in the overdose cases reported here.

KW - Adult

KW - Humans

KW - Male

KW - Fatal Outcome

KW - Suicide

KW - Amphetamines/analysis/chemistry/metabolism

KW - Gas Chromatography-Mass Spectrometry/methods

KW - Monoamine Oxidase Inhibitors/chemistry/metabolism/poisoning

KW - Tranylcypromine/chemistry/metabolism/poisoning

KW - Adult

KW - Humans

KW - Male

KW - Fatal Outcome

KW - Suicide

KW - Amphetamines/analysis/chemistry/metabolism

KW - Gas Chromatography-Mass Spectrometry/methods

KW - Monoamine Oxidase Inhibitors/chemistry/metabolism/poisoning

KW - Tranylcypromine/chemistry/metabolism/poisoning

M3 - SCORING: Journal article

VL - 20

SP - 301

EP - 304

JO - J ANAL TOXICOL

JF - J ANAL TOXICOL

SN - 0146-4760

IS - 5

M1 - 5

ER -