Obsessive-compulsive disorder and posttraumatic stress disorder.
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Obsessive-compulsive disorder and posttraumatic stress disorder. / Grabe, Hans Joergen; Ruhrmann, Stephan; Spitzer, Carsten; Josepeit, Jana; Ettelt, Susan; Buhtz, Friederike; Hochrein, Andrea; Schulze-Rauschenbach, Svenja; Meyer, Klaus; Kraft, Susanne; Reck, Claudia; Pukrop, Ralf; Klosterkötter, Joachim; Falkai, Peter; Maier, Wolfgang; Wagner, Michael; John, Ulrich; Freyberger, Harald J.
In: PSYCHOPATHOLOGY, Vol. 41, No. 2, 2, 2008, p. 129-134.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Obsessive-compulsive disorder and posttraumatic stress disorder.
AU - Grabe, Hans Joergen
AU - Ruhrmann, Stephan
AU - Spitzer, Carsten
AU - Josepeit, Jana
AU - Ettelt, Susan
AU - Buhtz, Friederike
AU - Hochrein, Andrea
AU - Schulze-Rauschenbach, Svenja
AU - Meyer, Klaus
AU - Kraft, Susanne
AU - Reck, Claudia
AU - Pukrop, Ralf
AU - Klosterkötter, Joachim
AU - Falkai, Peter
AU - Maier, Wolfgang
AU - Wagner, Michael
AU - John, Ulrich
AU - Freyberger, Harald J
PY - 2008
Y1 - 2008
N2 - BACKGROUND: Previous studies suggested an association between exposure to trauma or stressful life events and obsessive-compulsive disorder (OCD). This study investigates the hypothesis that traumatic events and posttraumatic stress disorders (PTSD) precede the onset of OCD. SAMPLING AND METHODS: 210 cases with OCD from university treatment facilities were compared with 133 sex- and age-matched controls from the adult general population. The data were derived from a German family study on OCD (GENOS). Direct interviews were carried out with the German version of the Schedule for Affective Disorders and Schizophrenia - Lifetime Version for Anxiety Disorders (DSM-IV). RESULTS: Severe traumatization occurred in 6.2% of the OCD cases and in 8.3% of the controls. The lifetime prevalence rates of traumatization, PTSD and acute stress disorder were not different between the subjects with OCD and controls (p > 0.05). In 6 cases, acute stress disorder, subclinical or full PTSD preceded the onset of OCD, in 3 cases the trauma-related disorders and OCD occurred within the same year, in 5 other cases, the trauma-related disorders started after the onset of OCD. CONCLUSION: There is no significant association of traumatization or PTSD with OCD compared with controls. Given the low rate of trauma-related disorders occurring before (2.9%) or within (1.5%) the same year as the onset of OCD other factors than severe traumatic events determine the onset of OCD in most of the cases.
AB - BACKGROUND: Previous studies suggested an association between exposure to trauma or stressful life events and obsessive-compulsive disorder (OCD). This study investigates the hypothesis that traumatic events and posttraumatic stress disorders (PTSD) precede the onset of OCD. SAMPLING AND METHODS: 210 cases with OCD from university treatment facilities were compared with 133 sex- and age-matched controls from the adult general population. The data were derived from a German family study on OCD (GENOS). Direct interviews were carried out with the German version of the Schedule for Affective Disorders and Schizophrenia - Lifetime Version for Anxiety Disorders (DSM-IV). RESULTS: Severe traumatization occurred in 6.2% of the OCD cases and in 8.3% of the controls. The lifetime prevalence rates of traumatization, PTSD and acute stress disorder were not different between the subjects with OCD and controls (p > 0.05). In 6 cases, acute stress disorder, subclinical or full PTSD preceded the onset of OCD, in 3 cases the trauma-related disorders and OCD occurred within the same year, in 5 other cases, the trauma-related disorders started after the onset of OCD. CONCLUSION: There is no significant association of traumatization or PTSD with OCD compared with controls. Given the low rate of trauma-related disorders occurring before (2.9%) or within (1.5%) the same year as the onset of OCD other factors than severe traumatic events determine the onset of OCD in most of the cases.
M3 - SCORING: Zeitschriftenaufsatz
VL - 41
SP - 129
EP - 134
JO - PSYCHOPATHOLOGY
JF - PSYCHOPATHOLOGY
SN - 0254-4962
IS - 2
M1 - 2
ER -