Novel aspects of brown adipose tissue biology

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Novel aspects of brown adipose tissue biology. / Heeren, Joerg; Münzberg, Heike.

In: ENDOCRIN METAB CLIN, Vol. 42, No. 1, 01.03.2013, p. 89-107.

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@article{ea87dee4d20641329bb503f2af2d1373,
title = "Novel aspects of brown adipose tissue biology",
abstract = "During the last decades, obesity research has focused on food intake regulation, whereas energy expenditure has been mainly measured based on whole-body oxygen consumption. With the renaissance of brown adipose tissue (BAT) thermogenesis as a potential drug target in humans, more thought is put into alternative heat-producing mechanisms. Also, the interaction of peripheral and central components to regulate thermogenesis requires further studies. Certainly, several of the novel molecular genetic tools available now, compared with 40 years ago, will be helpful to gain new insights in BAT-controlled energy homeostasis and promises new approaches to pharmacologically control body weight.",
keywords = "Adipocytes, Adipose Tissue, Brown, Adipose Tissue, White, Animals, Body Temperature Regulation, Energy Metabolism, Humans, Thermogenesis",
author = "Joerg Heeren and Heike M{\"u}nzberg",
note = "Copyright {\textcopyright} 2013 Elsevier Inc. All rights reserved.",
year = "2013",
month = mar,
day = "1",
doi = "10.1016/j.ecl.2012.11.004",
language = "English",
volume = "42",
pages = "89--107",
journal = "ENDOCRIN METAB CLIN",
issn = "0889-8529",
publisher = "W B SAUNDERS CO-ELSEVIER INC",
number = "1",

}

RIS

TY - JOUR

T1 - Novel aspects of brown adipose tissue biology

AU - Heeren, Joerg

AU - Münzberg, Heike

N1 - Copyright © 2013 Elsevier Inc. All rights reserved.

PY - 2013/3/1

Y1 - 2013/3/1

N2 - During the last decades, obesity research has focused on food intake regulation, whereas energy expenditure has been mainly measured based on whole-body oxygen consumption. With the renaissance of brown adipose tissue (BAT) thermogenesis as a potential drug target in humans, more thought is put into alternative heat-producing mechanisms. Also, the interaction of peripheral and central components to regulate thermogenesis requires further studies. Certainly, several of the novel molecular genetic tools available now, compared with 40 years ago, will be helpful to gain new insights in BAT-controlled energy homeostasis and promises new approaches to pharmacologically control body weight.

AB - During the last decades, obesity research has focused on food intake regulation, whereas energy expenditure has been mainly measured based on whole-body oxygen consumption. With the renaissance of brown adipose tissue (BAT) thermogenesis as a potential drug target in humans, more thought is put into alternative heat-producing mechanisms. Also, the interaction of peripheral and central components to regulate thermogenesis requires further studies. Certainly, several of the novel molecular genetic tools available now, compared with 40 years ago, will be helpful to gain new insights in BAT-controlled energy homeostasis and promises new approaches to pharmacologically control body weight.

KW - Adipocytes

KW - Adipose Tissue, Brown

KW - Adipose Tissue, White

KW - Animals

KW - Body Temperature Regulation

KW - Energy Metabolism

KW - Humans

KW - Thermogenesis

U2 - 10.1016/j.ecl.2012.11.004

DO - 10.1016/j.ecl.2012.11.004

M3 - SCORING: Journal article

C2 - 23391242

VL - 42

SP - 89

EP - 107

JO - ENDOCRIN METAB CLIN

JF - ENDOCRIN METAB CLIN

SN - 0889-8529

IS - 1

ER -