No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.

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No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe. / Stieler, Kristin; Schindler, Sarah; Schlomm, Thorsten; Hohn, Oliver; Bannert, Norbert; Simon, Ronald; Minner, Sarah Jane Pauline; Schindler, Michael; Fischer, Nicole.

In: PLOS ONE, Vol. 6, No. 10, 10, 2011, p. 25592.

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@article{9b36194b0d554fc5a4580114aa722fde,
title = "No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.",
abstract = "We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The controversial discussion about the virus being detected in PCA tissue, blood samples from patients suffering from chronic fatigue syndrome (CFS), as well as from a significant number of healthy controls prompted us to deepen our studies about detection of XMRV infection applying different detection methods (PCR, cocultivation and immunohistochemistry [IHC]).",
keywords = "Adult, Humans, Male, Aged, Middle Aged, Europe, Immunohistochemistry, Cell Line, Tumor, Coculture Techniques, Case-Control Studies, Polymerase Chain Reaction, Cell Separation, Leukocytes, Mononuclear/virology, Lymphocyte Activation/immunology, Prostate/*pathology/*virology, Prostatic Neoplasms/*blood/pathology/*virology, Retroviridae Infections/virology, Viral Proteins/metabolism, Virus Replication, Xenotropic murine leukemia virus-related virus/genetics/*isolation & purification/physiology, Adult, Humans, Male, Aged, Middle Aged, Europe, Immunohistochemistry, Cell Line, Tumor, Coculture Techniques, Case-Control Studies, Polymerase Chain Reaction, Cell Separation, Leukocytes, Mononuclear/virology, Lymphocyte Activation/immunology, Prostate/*pathology/*virology, Prostatic Neoplasms/*blood/pathology/*virology, Retroviridae Infections/virology, Viral Proteins/metabolism, Virus Replication, Xenotropic murine leukemia virus-related virus/genetics/*isolation & purification/physiology",
author = "Kristin Stieler and Sarah Schindler and Thorsten Schlomm and Oliver Hohn and Norbert Bannert and Ronald Simon and Minner, {Sarah Jane Pauline} and Michael Schindler and Nicole Fischer",
year = "2011",
doi = "10.1371/journal.pone.0025592",
language = "English",
volume = "6",
pages = "25592",
journal = "PLOS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "10",

}

RIS

TY - JOUR

T1 - No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.

AU - Stieler, Kristin

AU - Schindler, Sarah

AU - Schlomm, Thorsten

AU - Hohn, Oliver

AU - Bannert, Norbert

AU - Simon, Ronald

AU - Minner, Sarah Jane Pauline

AU - Schindler, Michael

AU - Fischer, Nicole

PY - 2011

Y1 - 2011

N2 - We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The controversial discussion about the virus being detected in PCA tissue, blood samples from patients suffering from chronic fatigue syndrome (CFS), as well as from a significant number of healthy controls prompted us to deepen our studies about detection of XMRV infection applying different detection methods (PCR, cocultivation and immunohistochemistry [IHC]).

AB - We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The controversial discussion about the virus being detected in PCA tissue, blood samples from patients suffering from chronic fatigue syndrome (CFS), as well as from a significant number of healthy controls prompted us to deepen our studies about detection of XMRV infection applying different detection methods (PCR, cocultivation and immunohistochemistry [IHC]).

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Europe

KW - Immunohistochemistry

KW - Cell Line, Tumor

KW - Coculture Techniques

KW - Case-Control Studies

KW - Polymerase Chain Reaction

KW - Cell Separation

KW - Leukocytes, Mononuclear/virology

KW - Lymphocyte Activation/immunology

KW - Prostate/pathology/virology

KW - Prostatic Neoplasms/blood/pathology/virology

KW - Retroviridae Infections/virology

KW - Viral Proteins/metabolism

KW - Virus Replication

KW - Xenotropic murine leukemia virus-related virus/genetics/isolation & purification/physiology

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Europe

KW - Immunohistochemistry

KW - Cell Line, Tumor

KW - Coculture Techniques

KW - Case-Control Studies

KW - Polymerase Chain Reaction

KW - Cell Separation

KW - Leukocytes, Mononuclear/virology

KW - Lymphocyte Activation/immunology

KW - Prostate/pathology/virology

KW - Prostatic Neoplasms/blood/pathology/virology

KW - Retroviridae Infections/virology

KW - Viral Proteins/metabolism

KW - Virus Replication

KW - Xenotropic murine leukemia virus-related virus/genetics/isolation & purification/physiology

U2 - 10.1371/journal.pone.0025592

DO - 10.1371/journal.pone.0025592

M3 - SCORING: Journal article

VL - 6

SP - 25592

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 10

M1 - 10

ER -